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E0TNH4

- E0TNH4_STRZ6

UniProt

E0TNH4 - E0TNH4_STRZ6

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, SP670_1271
Organism
Streptococcus pneumoniae (strain 670-6B)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei561 – 5611 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciSPNE189423:GHX7-1266-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:SP670_1271Imported
OrganismiStreptococcus pneumoniae (strain 670-6B)Imported
Taxonomic identifieri189423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002232: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiSILNCET.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0TNH4-1 [UniParc]FASTAAdd to Basket

« Hide

MSLQKLENYS NKSVVQEEVL ILTELLEDIT KNMLAPETFE KIIQLKELST    50
QEDYQGLNRL VTSLSNDEMV YISRYFSILP LLINISEDVD LAYEINHQNN 100
IDQDYLGKLS TTIKLVAEKE NAVEILEHLN VVPVLTAHPT QVQRKSMLDL 150
TNHIHSLLRK YRDVKLGLIN KDKWYNDLRR YIEIIMQTDM IREKKLKVTN 200
EITNAMEYYN SSFLKAVPHL TTEYKRLAQA HGLNLKQAKP ITMGMWIGGD 250
RDGNPFVTAK TLKQSALTQC EVIMNYYDKK IYQLYREFSL STSIVNVSKQ 300
VREMARQSKD NSIYREKELY RRALFDIQSK IQATKTYLIE DEEVGTRYET 350
ANDFYKDLIA IRDSLLENKG ESLISGDFVE LLQAVEIFGF YLASIDMRQD 400
SSVYEACVAE LLKSAGIHSR YSELSEEEKC DLLLKELEED PRILSATHAE 450
KSELLAKELA IFKTARVLKD KLGDDVIRQT IISHATSLSD MLELAILLKE 500
VGLVDTERAR VQIVPLFETI EDLDHSEETM RKYLSLSLAK KWIDSRNNYQ 550
EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKV TFFHGRGGTV 600
GRGGGPTYEA ITSQPLKSIK DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV 650
SAAINRMITQ KKSDTNTPNR YEAIMDQVVD RSYDVYRDLV FGNEHFYDYF 700
FESSPIKAIS SFNIGSRPAA RKTITEIGGL RAIPWVFSWS QSRVMFPGWY 750
GVGSSFKEFI NKNPENIAIL RDMYQNWPFF QSLLSNVDMV LSKSNMNIAF 800
EYAKLCEDEQ VKAIYETILN EWQVTKNVIL AIEGHDELLA DNPYLKASLD 850
YRMPYFNILN YIQLELIKRQ RRGELSSDQE RLIHITINGI ATGLRNSG 898
Length:898
Mass (Da):103,271
Last modified:November 2, 2010 - v1
Checksum:iF7FD1F552BF04E62
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002176 Genomic DNA. Translation: ADM91332.1.
RefSeqiYP_003879432.1. NC_014498.1.

Genome annotation databases

EnsemblBacteriaiADM91332; ADM91332; SP670_1271.
GeneIDi9729989.
KEGGisnb:SP670_1271.
PATRICi42516697. VBIStrPne54539_1337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002176 Genomic DNA. Translation: ADM91332.1 .
RefSeqi YP_003879432.1. NC_014498.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADM91332 ; ADM91332 ; SP670_1271 .
GeneIDi 9729989.
KEGGi snb:SP670_1271.
PATRICi 42516697. VBIStrPne54539_1337.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.
OMAi SILNCET.

Enzyme and pathway databases

BioCyci SPNE189423:GHX7-1266-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species."
    Neuendorf B., Radune D., Fedorova N.B., Khouri H.M., Dodson R.J., Daugherty S.C., Hollingshead S., Tettelin H.
    Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 670-6BImported.

Entry informationi

Entry nameiE0TNH4_STRZ6
AccessioniPrimary (citable) accession number: E0TNH4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: June 11, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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