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Protein
Submitted name:

Sialidase B

Gene

SP670_0950

Organism
Streptococcus pneumoniae (strain 670-6B)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Enzyme and pathway databases

BioCyciSPNE189423:GHX7-946-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase BImported (EC:3.2.1.18Imported)
Gene namesi
Ordered Locus Names:SP670_0950Imported
OrganismiStreptococcus pneumoniae (strain 670-6B)Imported
Taxonomic identifieri189423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002232 Componenti: Chromosome

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000285031.
KOiK01186.
OMAiSISEVQH.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.40.220.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR002860. BNR_rpt.
IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR023364. Trans_sialidase_dom3.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02012. BNR. 1 hit.
PF02973. Sialidase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.

Sequencei

Sequence statusi: Complete.

E0TMG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKNIKQYVT LGTVVVLSAF VANSVAAQET ETSEVSTPKL VQPVAPTTPI
60 70 80 90 100
SEVQPTSDNS SEVTVQPRTV ETTVKDPSST AEETPVLEKN NVTLTGGGEN
110 120 130 140 150
VTKELKDKFT SGDFTVVIKY NQSSEKGLQA LFGISNSKPG QQNSYVDVFL
160 170 180 190 200
RDNGELGMEA RDTSSNKNNL VSRPASVWGK YKQEAVTNTV AVVADSVKKT
210 220 230 240 250
YSLYANGTKV VEKKMDNFLN IKDIKGIDYY MLGGVKRAGK TAFGFNGTLE
260 270 280 290 300
NIKFFNSALD EETVKKMTTN AVTGHLIYTA NDTTGSNYFR IPVLYTFSNG
310 320 330 340 350
RVFSSIDARY GGTHDFLNKI NIATSYSDDN GKTWTKPKLT LAFDDFAPVP
360 370 380 390 400
LEWPREVGGR DLQISGGATY IDSVIVEKKN KQVLMFADVM PAGVSFREAT
410 420 430 440 450
RKDSGYKQID GNYYLKLRKQ GDTDYNYTIR ENGTVYDDRT NRPTEFSVDK
460 470 480 490 500
NFGIKQNGNY LTVEQYSVSF ENNKKTEYRN GTKVHMNIFY KDALFKVVPT
510 520 530 540 550
NYIAYISSND HGESWSAPTL LPPIMGLNRN APYLGPGRGI IESSTGRILI
560 570 580 590 600
PSYTGKESAF IYSDDNGASW KVKVVPLPSS WSAEAQFVEL SPGVIQAYMR
610 620 630 640 650
TNNGKIAYLT SKDAGTTWSA PEYLKFVSNP SYGTQLSIIN YSQLIDGKKA
660 670 680 690 700
VILSTPNSTN GRKHGQIWIG LINDDNTIDW RYHHDVDYSN YGYSYSTLTE
710 720 730 740
LPNHEIGLMF EKFDSWSRNE LHMKNVVPYI TFKIEDLKKN
Length:740
Mass (Da):82,470
Last modified:November 2, 2010 - v1
Checksum:i96001837A55A6B50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002176 Genomic DNA. Translation: ADM91015.1.
RefSeqiYP_003879115.1. NC_014498.1.

Genome annotation databases

EnsemblBacteriaiADM91015; ADM91015; SP670_0950.
KEGGisnb:SP670_0950.
PATRICi42516020. VBIStrPne54539_1005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002176 Genomic DNA. Translation: ADM91015.1.
RefSeqiYP_003879115.1. NC_014498.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADM91015; ADM91015; SP670_0950.
KEGGisnb:SP670_0950.
PATRICi42516020. VBIStrPne54539_1005.

Phylogenomic databases

HOGENOMiHOG000285031.
KOiK01186.
OMAiSISEVQH.

Enzyme and pathway databases

BioCyciSPNE189423:GHX7-946-MONOMER.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.40.220.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR002860. BNR_rpt.
IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR023364. Trans_sialidase_dom3.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02012. BNR. 1 hit.
PF02973. Sialidase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species."
    Neuendorf B., Radune D., Fedorova N.B., Khouri H.M., Dodson R.J., Daugherty S.C., Hollingshead S., Tettelin H.
    Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 670-6BImported.

Entry informationi

Entry nameiE0TMG6_STRZ6
AccessioniPrimary (citable) accession number: E0TMG6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: April 1, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.