Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E0SRG9

- E0SRG9_IGNAA

UniProt

E0SRG9 - E0SRG9_IGNAA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ribulose bisphosphate carboxylase

Gene

rbcL

Organism
Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the addition of molecular CO2 and H2O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Note: Binds 1 magnesium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei163 – 1631Proton acceptorUniRule annotation
Binding sitei165 – 1651SubstrateUniRule annotation
Metal bindingi189 – 1891Magnesium; via carbamate groupUniRule annotation
Metal bindingi191 – 1911MagnesiumUniRule annotation
Metal bindingi192 – 1921MagnesiumUniRule annotation
Active sitei281 – 2811Proton acceptorUniRule annotation
Binding sitei282 – 2821SubstrateUniRule annotation
Binding sitei314 – 3141SubstrateUniRule annotation
Sitei322 – 3221Transition state stabilizerUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. oxidoreductase activity Source: UniProtKB-KW
  3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. AMP catabolic process Source: UniProtKB-HAMAP
  2. carbon fixation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, OxidoreductaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciIAGG583356:GHAH-1667-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylaseUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCOUniRule annotation
Gene namesi
Name:rbcLUniRule annotation
Ordered Locus Names:Igag_1625Imported
OrganismiIgnisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1)Imported
Taxonomic identifieri583356 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeIgnisphaera
ProteomesiUP000001304: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei189 – 1891N6-carboxylysineUniRule annotation

Interactioni

Subunit structurei

Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE0SRG9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni367 – 3693Substrate bindingUniRule annotation
Regioni389 – 3924Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the RuBisCO large chain family.UniRule annotation
Belongs to the RuBisCO large chain family. Type III subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000230831.
KOiK01601.
OMAiIFRESHY.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProiIPR017712. RuBisCO_III.
IPR020878. RuBisCo_large_chain_AS.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
TIGRFAMsiTIGR03326. rubisco_III. 1 hit.
PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0SRG9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKPDFEPYS AWVEKSYTPD PKSDVIVTFR ITPAEGFTIE DVAGGVAAES
60 70 80 90 100
STGTWTTLYP WYDENRLRRL RGKAYAFKDL GDGSYLVRIA YPVELFEEGN
110 120 130 140 150
MPVFLASVAG NIFGMRRAKY LRVEDIYMPY DFIKYFKGPV KGIQGVRDTL
160 170 180 190 200
KVYDRPIVGT VPKPKVGYTA DEVEKLAYEI LSGGMDFIKD DENLGGPSYC
210 220 230 240 250
RFEARAKAIM KIIDKVEKET GERKVWLANI TADVREMEKR LKLVADYGNP
260 270 280 290 300
VIMVDVVIVG WASLGYIRDL AEEYKLYIHA HRAMHAAITR NPYHGISMFT
310 320 330 340 350
LAKLFRIIGV DQLHIGTPEV GKLEARTIDV IRNAKVLREN PFKPDKDDDF
360 370 380 390 400
HLEQEFYHIK PALPTSSGGL HPGTLPEVVR VMGKDLVIQV GGGTIGHPDG
410 420 430 440
PRAGAMAVRQ ALEAIAKGIP LDEYAKDHKE LRRALEKWGY VKPI
Length:444
Mass (Da):49,904
Last modified:November 2, 2010 - v1
Checksum:iF7A8190E2F7FE850
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002098 Genomic DNA. Translation: ADM28423.1.
RefSeqiWP_013304073.1. NC_014471.1.
YP_003860303.1. NC_014471.1.

Genome annotation databases

EnsemblBacteriaiADM28423; ADM28423; Igag_1625.
GeneIDi9716941.
KEGGiiag:Igag_1625.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002098 Genomic DNA. Translation: ADM28423.1 .
RefSeqi WP_013304073.1. NC_014471.1.
YP_003860303.1. NC_014471.1.

3D structure databases

ProteinModelPortali E0SRG9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADM28423 ; ADM28423 ; Igag_1625 .
GeneIDi 9716941.
KEGGi iag:Igag_1625.

Phylogenomic databases

HOGENOMi HOG000230831.
KOi K01601.
OMAi IFRESHY.

Enzyme and pathway databases

BioCyci IAGG583356:GHAH-1667-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProi IPR017712. RuBisCO_III.
IPR020878. RuBisCo_large_chain_AS.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
TIGRFAMsi TIGR03326. rubisco_III. 1 hit.
PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17230 / JCM 13409 / AQ1.S1Imported.

Entry informationi

Entry nameiE0SRG9_IGNAA
AccessioniPrimary (citable) accession number: E0SRG9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: November 26, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O2 to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3