E0SJQ4 (E0SJQ4_DICD3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Gamma-aminobutyric-acid receptor subunit beta-1 EMBL ADN00343.1

Gene names

Ordered Locus Names:

Dda3937_00520

Organism

Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) [Complete proteome] [HAMAP] EMBL ADN00343.1

Taxonomic identifier

198628 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Dickeya › Dickeya dadantii

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Receptor EMBL ADN00343.1
Technical term	3D-structure PDB 3RQU PDB 3RQW PDB 3UQ4 PDB 3UQ5 PDB 3UQ7 PDB 2YN6 Complete proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	extracellular ligand-gated ion channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E0SJQ4 [UniParc]. Last modified November 2, 2010. Version 1. Checksum: 90663D9956C5C82E	FASTA	343	39,175
	10 20 30 40 50 60 MRILWSCCGL VLLLLGLPAW SAPADNAADA RPVDVSVSIF INKIYGVNTL EQTYKVDGYI 70 80 90 100 110 120 VAQWTGKPRK TPGDKPLIVE NTQIERWINN GLWVPALEFI NVVGSPDTGN KRLMLFPDGR 130 140 150 160 170 180 VIYNARFLGS FSNDMDFRLF PFDRQQFVLE LEPFSYNNQQ LRFSDIQVYT ENIDNEEIDE 190 200 210 220 230 240 WWIRGKASTH ISDIRYDHLS SVQPNQNEFS RITVRIDAVR NPSYYLWSFI LPLGLIIAAS 250 260 270 280 290 300 WSVFWLESFS ERLQTSFTLM LTVVAYAFYT SNILPRLPYT TVIDQMIIAG YGSIFAAILL 310 320 330 340 IIFAHHRQAN GVEDDLLIQR CRLAFPLGFL AIGCVLVIRG ITL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937." Glasner J.D., Yang C.H., Reverchon S., Hugouvieux-Cotte-Pattat N., Condemine G., Bohin J.P., Van Gijsegem F., Yang S., Franza T., Expert D., Plunkett G. III, San Francisco M.J., Charkowski A.O., Py B., Bell K., Rauscher L., Rodriguez-Palenzuela P., Toussaint A. , Holeva M.C., He S.Y., Douet V., Boccara M., Blanco C., Toth I., Anderson B.D., Biehl B.S., Mau B., Flynn S.M., Barras F., Lindeberg M., Birch P.R., Tsuyumu S., Shi X., Hibbing M., Yap M.N., Carpentier M., Dassa E., Umehara M., Kim J.F., Rusch M., Soni P., Mayhew G.F., Fouts D.E., Gill S.R., Blattner F.R., Keen N.T., Perna N.T. J. Bacteriol. 193:2076-2077(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 3937.
[2]	"Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine." Pan J., Chen Q., Willenbring D., Yoshida K., Tillman T., Kashlan O.B., Cohen A., Kong X.P., Xu Y., Tang P. Nat. Commun. 3:714-714(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.91 ANGSTROMS) OF 22-343.
[3]	"Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations." Zimmermann I., Marabelli A., Bertozzi C., Sivilotti L.G., Dutzler R. PLoS Biol. 10:e1001429-e1001429(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.31 ANGSTROMS) OF 22-343.
[4]	"Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals." Gonzalez-Gutierrez G., Lukk T., Agarwal V., Papke D., Nair S.K., Grosman C. Proc. Natl. Acad. Sci. U.S.A. 109:6331-6336(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.50 ANGSTROMS) OF 21-343.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP002038 Genomic DNA. Translation: ADN00343.1.

RefSeq

YP_003884899.1. NC_014500.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2YN6	X-ray	3.31	A/B/C/D/E	22-343	[»]
3RQU	X-ray	3.09	A/B/C/D/E/F/G/H/I/J	22-343	[»]
3RQW	X-ray	2.91	A/B/C/D/E/F/G/H/I/J	22-343	[»]
3UQ4	X-ray	3.50	A/B/C/D/E/F/G/H/I/J	21-343	[»]
3UQ5	X-ray	4.20	A/B/C/D/E/F/G/H/I/J	21-343	[»]
3UQ7	X-ray	3.80	A/B/C/D/E/F/G/H/I/J	21-343	[»]

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ADN00343; ADN00343; Dda3937_00520.

GeneID

9735629.

KEGG

ddd:Dda3937_00520.

PATRIC

42320599. VBIDicDad25310_4084.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

HOG000157201.

OMA

ISFTYEA.

Enzyme and pathway databases

BioCyc

DDAD198628:GHFQ-4243-MONOMER.

Family and domain databases

Gene3D

2.70.170.10. 1 hit.

InterPro

IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
[Graphical view]

PANTHER

PTHR18945. PTHR18945. 1 hit.

Pfam

PF02931. Neur_chan_LBD. 1 hit.
[Graphical view]

SUPFAM

SSF90112. Neu_channel_TM. 1 hit.
SSF63712. Neur_chan_LBD. 1 hit.

ProtoNet

Search...

Entry information

Entry name

E0SJQ4_DICD3

Accession

Primary (citable) accession number: E0SJQ4

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 2, 2010
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)