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E0SEU7 (E0SEU7_DICD3) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Leucine--tRNA ligase HAMAP-Rule MF_00049
EC=6.1.1.4 HAMAP-Rule MF_00049
Alternative name(s):
Leucyl-tRNA synthetase HAMAP-Rule MF_00049
Gene names
Name:leuS HAMAP-Rule MF_00049
Ordered Locus Names:Dda3937_02477
OrganismDickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) [Complete proteome] [HAMAP] EMBL ADM97509.1
Taxonomic identifier198628 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Dickeya ›

Protein attributes

Sequence length860 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu). HAMAP-Rule MF_00049

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00049.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00049 RuleBase RU003489

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif42 – 5211"HIGH" region By similarity HAMAP-Rule MF_00049
Motif619 – 6235"KMSKS" region By similarity HAMAP-Rule MF_00049

Sites

Binding site6221ATP By similarity HAMAP-Rule MF_00049

Sequences

Sequence LengthMass (Da)Tools
E0SEU7 [UniParc].

Last modified November 2, 2010. Version 1.
Checksum: D11C7A62D955B78A

FASTA86097,258
        10         20         30         40         50         60 
MQEQYRPEEI EAHVQLHWQE KQTFKVTEEP GKEKYYCLSM LPYPSGRLHM GHVRNYTIGD 

        70         80         90        100        110        120 
VISRYQRMLG KNVLQPIGWD AFGLPAEGAA VKNNTAPAPW TYANIEYMKN QLKLLGFGYD 

       130        140        150        160        170        180 
WDREVATCKP DYYRWEQWFF TKLYEKGLVY KKTSAVNWCP NDQTVLANEQ VIDGCCWRCD 

       190        200        210        220        230        240 
TKVERKEIPQ WFIKITAYAD ELLNDLDTLE SWPEQVKTMQ RNWIGRSEGV EITFDVADSE 

       250        260        270        280        290        300 
EKLSVYTTRP DTFMGVTYVA VAAGHPLAQK AAENNPALRD FIAECGNTKM AEADMATMEK 

       310        320        330        340        350        360 
KGIATGLFAV HPLTGENVPV WAANFVLMEY GTGAVMAVPG HDQRDWEFAH KYNLPVKPVI 

       370        380        390        400        410        420 
LMADGSEPDL SAQAQTEKGR LFNSGEFDGL DFDAAFNAIA DKLVSQGVGQ RKVNYRLRDW 

       430        440        450        460        470        480 
GVSRQRYWGA PIPMMTLEDG TVVPTPEDQL PVILPEDVVM DGITSPIKAD PEWAKTTFNG 

       490        500        510        520        530        540 
QPALRETDTF DTFMESSWYY ARYTCPQYDQ GMLDPAAANY WLPVDQYVGG IEHAILHLMY 

       550        560        570        580        590        600 
FRFFHKLMRD AGLVNSNEPA KRLLCQGMVL ADAFYHAGNN GERIWVSPSD VTLERDDKGR 

       610        620        630        640        650        660 
ITKAFDKDGR ELVYAGMSKM SKSKNNGIDP QVMVERYGAD TVRLFMMFAS PAEMTLEWQE 

       670        680        690        700        710        720 
SGVEGANRFL KRVWKQVYDH TGKGAAQPLD TAALTEDQKA LRRDLHKTIA KVTDDIGRRQ 

       730        740        750        760        770        780 
TFNTAIAAIM ELMNKLAKAS QESEQDRALT QETLLAVVRM LYPFTPHACF VLWRELQGEG 

       790        800        810        820        830        840 
DIDLAPWPVA DEQAMVEDSR LVVVQVNGKV RGKITVAADA TEQQVRDRAA QEPLVAKYLD 

       850        860 
GVTVRKVIFV PGKLLNLVVG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002038 Genomic DNA. Translation: ADM97509.1.
RefSeqYP_003882066.1. NC_014500.1.

3D structure databases

ProteinModelPortalE0SEU7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADM97509; ADM97509; Dda3937_02477.
GeneID9732719.
KEGGddd:Dda3937_02477.
PATRIC42314954. VBIDicDad25310_1308.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000200747.
KOK01869.
OMAGWPEQVK.

Enzyme and pathway databases

BioCycDDAD198628:GHFQ-1333-MONOMER.

Family and domain databases

Gene3D3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPMF_00049_B. Leu_tRNA_synth_B.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase_bac/mito.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSPR00985. TRNASYNTHLEU.
SUPFAMSSF47323. tRNAsyn_1a_bind. 1 hit.
SSF50677. ValRS_IleRS_edit. 1 hit.
TIGRFAMsTIGR00396. leuS_bact. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE0SEU7_DICD3
AccessionPrimary (citable) accession number: E0SEU7
Entry history
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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