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Protein

2-dehydro-3-deoxyphosphooctonate aldolase

Gene

kdsA

Organism
Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate.UniRule annotationSAAS annotation

Pathwayi: lipopolysaccharide biosynthesis

This protein is involved in the pathway lipopolysaccharide biosynthesis, which is part of Bacterial outer membrane biogenesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway lipopolysaccharide biosynthesis and in Bacterial outer membrane biogenesis.

Pathwayi: 3-deoxy-D-manno-octulosonate biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate.UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. 2-dehydro-3-deoxyphosphooctonate aldolase (kdsA)
  3. 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC (kdsC)
This subpathway is part of the pathway 3-deoxy-D-manno-octulosonate biosynthesis, which is itself part of Carbohydrate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate, the pathway 3-deoxy-D-manno-octulosonate biosynthesis and in Carbohydrate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationSAAS annotationImported
Biological processLipopolysaccharide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00030.
UPA00357; UER00474.

Names & Taxonomyi

Protein namesi
Recommended name:
2-dehydro-3-deoxyphosphooctonate aldolaseUniRule annotation (EC:2.5.1.55UniRule annotation)
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthaseUniRule annotation
KDO-8-phosphate synthaseUniRule annotation
Short name:
KDO 8-P synthaseUniRule annotation
Short name:
KDOPSUniRule annotation
Phospho-2-dehydro-3-deoxyoctonate aldolaseUniRule annotation
Gene namesi
Name:kdsAUniRule annotationImported
Ordered Locus Names:Dda3937_00038Imported
OrganismiDickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))Imported
Taxonomic identifieri198628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaeDickeya
Proteomesi
  • UP000006859 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi198628.Dda3937_00038.

Structurei

3D structure databases

ProteinModelPortaliE0SCL0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 275DAHP_synth_1InterPro annotationAdd BLAST261

Sequence similaritiesi

Belongs to the KdsA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CXR. Bacteria.
COG2877. LUCA.
HOGENOMiHOG000023021.
KOiK01627.
OMAiIKKPQFM.
OrthoDBiPOG091H00ND.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00056. KDO8P_synth. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
PANTHERiPTHR21057. PTHR21057. 1 hit.
PfamiView protein in Pfam
PF00793. DAHP_synth_1. 1 hit.
TIGRFAMsiTIGR01362. KDO8P_synth. 1 hit.

Sequencei

Sequence statusi: Complete.

E0SCL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNKVVNIGD IPVANSLPFV LFGGMNVLES RDLAMRICEH YVTVTQKLGI
60 70 80 90 100
PYVFKASFDK ANRSSIHSYR GPGLEAGMKI FQELKQTFGV KIITDVHEPQ
110 120 130 140 150
QAQPVSEVVD VIQLPAFLAR QTDLVEAMAK TDAVINIKKP QFISPGQVGN
160 170 180 190 200
IVDKFREGGN EQVILCDRGS NFGYDNLVVD MLGFNVMKQV SHGAPVIFDV
210 220 230 240 250
THALQCRDPF GAASGGRRAQ VAELARAGMA VGIAGLFIEA HPEPNSAMCD
260 270 280
GPSALPLTKL EPFLQQMKAI DELVKSFPEL DTSN
Length:284
Mass (Da):30,898
Last modified:November 2, 2010 - v1
Checksum:i44CCFEE22107CD1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002038 Genomic DNA. Translation: ADM98534.1.
RefSeqiWP_013317987.1. NC_014500.1.

Genome annotation databases

EnsemblBacteriaiADM98534; ADM98534; Dda3937_00038.
GeneIDi9733768.
KEGGiddd:Dda3937_00038.
PATRICifig|198628.6.peg.2312.

Similar proteinsi

Entry informationi

Entry nameiE0SCL0_DICD3
AccessioniPrimary (citable) accession number: E0SCL0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: September 27, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported