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E0RTD9 (E0RTD9_SPITD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339
Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA3 EMBL ADN01005.1
Synonyms:pfkA HAMAP-Rule MF_00339
Ordered Locus Names:STHERM_c00290 EMBL ADN01005.1
OrganismSpirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1) [Complete proteome] [HAMAP] EMBL ADN01005.1
Taxonomic identifier665571 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Spirochaeta ›

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339 SAAS SAAS012003

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding26 – 305ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding170 – 1745ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding187 – 20317ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1431Proton acceptor By similarity HAMAP-Rule MF_00339
Metal binding2011Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00339
Metal binding2031Magnesium By similarity HAMAP-Rule MF_00339
Binding site1781Substrate By similarity HAMAP-Rule MF_00339
Binding site2821Substrate By similarity HAMAP-Rule MF_00339
Binding site2881Substrate By similarity HAMAP-Rule MF_00339
Binding site2911Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
E0RTD9 [UniParc].

Last modified November 2, 2010. Version 1.
Checksum: 7D2B4DE9F78372AB

FASTA36639,845
        10         20         30         40         50         60 
MKRPATRTFG ILTSGGDCPG LNAAIRGVTK AAYWRYGMSI IGISHGYRGL IEGDARLLHP 

        70         80         90        100        110        120 
RDFDGILTRG GTILGTSREK PFKPDPGEKD SEAGSRKVEA IIENYHKLHL DCLVVLGGNG 

       130        140        150        160        170        180 
THKTAYLLQQ AGLNVIGLPK TIDNDIWGTD VTFGFHSAVD IATEAIDRLH STAHAHNRVM 

       190        200        210        220        230        240 
VIEVMGHKAG WLALYAGIAG GGDIILIPEI PYDLAHIVHH LQTRQQRGKE FSIVVVAEGA 

       250        260        270        280        290        300 
LSREESLMSK EERKKRRKKN RFPTKGYEVA HLIQEATGME TRVTVLGYLQ RGGTPSPYDR 

       310        320        330        340        350        360 
LLATRFGTAA AELLYRGDYG KMVALRDGEV VAIPLGEVAE KLKTVPPDHP LIDTARAVGT 


CFGDGV

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Spirochaeta thermophila DSM6192."
Angelov A., Mientus M., Wittenberg S., Lehmann R., Liesegang H., Daniel R., Liebl W.
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM 6192.
[2]"Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192."
Angelov A., Liebl S., Ballschmiter M., Bomeke M., Lehmann R., Liesegang H., Daniel R., Liebl W.
J. Bacteriol. 192:6492-6493(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49972 / DSM 6192 / RI 19.B1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001698 Genomic DNA. Translation: ADN01005.1.
RefSeqYP_003873278.1. NC_014484.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADN01005; ADN01005; STHERM_c00290.
GeneID9755283.
KEGGsta:STHERM_c00290.
PATRIC42519253. VBISpiThe146732_0030.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000248869.
KOK00850.
OMADRRVQLY.

Enzyme and pathway databases

UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR022953. Phosphofructokinase.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. Ppfruckinase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE0RTD9_SPITD
AccessionPrimary (citable) accession number: E0RTD9
Entry history
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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