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E0RQQ0 (E0RQQ0_SPITD) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site371Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2621Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1331Substrate By similarity HAMAP-Rule MF_01201
Binding site3101Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue371N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E0RQQ0 [UniParc].

Last modified November 2, 2010. Version 1.
Checksum: 6804E6A558002A4A

FASTA39142,496
        10         20         30         40         50         60 
MGVRGTHAVI YLSHLRHNLR EIRRRVGEGR MVCAAVKADA YGHGAVEVGK VLVEEGVEML 

        70         80         90        100        110        120 
GVATPEEGAE LAGVGARVLL LGLTDGAGLE LAVEAGLELA VGDREYVREV ARVARAKGRR 

       130        140        150        160        170        180 
VRVHVEVDTG MGRTGCAPEE AVGVVEEVEG AGVLELAGMW THFPSSDEAD DGFTEAQVER 

       190        200        210        220        230        240 
FLQVVGRVRA RGISPGLLHA ANSGGIIGHP PSWLDMVRPG ISLYGYYPSE EQERTLSLLP 

       250        260        270        280        290        300 
VMEFVSQVVF LKKVRKGTPV SYGRTWRAPR DTWIATVAAG YADGYSRLLS SRAEVLIRGR 

       310        320        330        340        350        360 
RYPVVGRVCM DQFMVDVGPH PRVRRYDRVV LFGPDPSGPS AEELARLVGT IPYEITCAVS 

       370        380        390 
RRVPRLYVEE SPYLSGGSSS AHRGGLTRYE R 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Spirochaeta thermophila DSM6192."
Angelov A., Mientus M., Wittenberg S., Lehmann R., Liesegang H., Daniel R., Liebl W.
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM 6192.
[2]"Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192."
Angelov A., Liebl S., Ballschmiter M., Bomeke M., Lehmann R., Liesegang H., Daniel R., Liebl W.
J. Bacteriol. 192:6492-6493(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49972 / DSM 6192 / RI 19.B1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001698 Genomic DNA. Translation: ADN01554.1.
RefSeqYP_003873827.1. NC_014484.1.

3D structure databases

ProteinModelPortalE0RQQ0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADN01554; ADN01554; STHERM_c05940.
GeneID9755848.
KEGGsta:STHERM_c05940.
PATRIC42520403. VBISpiThe146732_0589.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
OMAINNQLAP.

Enzyme and pathway databases

BioCycSTHE665571:GI3Y-594-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE0RQQ0_SPITD
AccessionPrimary (citable) accession number: E0RQQ0
Entry history
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: April 16, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)