E0RQQ0 (E0RQQ0_SPITD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr
Ordered Locus Names:	STHERM_c05940 EMBL ADN01554.1

Organism

Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1) [Complete proteome] [HAMAP] EMBL ADN01554.1

Taxonomic identifier

665571 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Spirochaetaceae › Spirochaeta › Spirochaeta thermophila

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622 RuleBase RU004247
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate SAAS SAAS020622 RuleBase RU000608
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E0RQQ0 [UniParc]. Last modified November 2, 2010. Version 1. Checksum: 6804E6A558002A4A	FASTA	391	42,496
	10 20 30 40 50 60 MGVRGTHAVI YLSHLRHNLR EIRRRVGEGR MVCAAVKADA YGHGAVEVGK VLVEEGVEML 70 80 90 100 110 120 GVATPEEGAE LAGVGARVLL LGLTDGAGLE LAVEAGLELA VGDREYVREV ARVARAKGRR 130 140 150 160 170 180 VRVHVEVDTG MGRTGCAPEE AVGVVEEVEG AGVLELAGMW THFPSSDEAD DGFTEAQVER 190 200 210 220 230 240 FLQVVGRVRA RGISPGLLHA ANSGGIIGHP PSWLDMVRPG ISLYGYYPSE EQERTLSLLP 250 260 270 280 290 300 VMEFVSQVVF LKKVRKGTPV SYGRTWRAPR DTWIATVAAG YADGYSRLLS SRAEVLIRGR 310 320 330 340 350 360 RYPVVGRVCM DQFMVDVGPH PRVRRYDRVV LFGPDPSGPS AEELARLVGT IPYEITCAVS 370 380 390 RRVPRLYVEE SPYLSGGSSS AHRGGLTRYE R

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Spirochaeta thermophila DSM6192." Angelov A., Mientus M., Wittenberg S., Lehmann R., Liesegang H., Daniel R., Liebl W. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: DSM 6192.
[2]	"Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192." Angelov A., Liebl S., Ballschmiter M., Bomeke M., Lehmann R., Liesegang H., Daniel R., Liebl W. J. Bacteriol. 192:6492-6493(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49972 / DSM 6192 / RI 19.B1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001698 Genomic DNA. Translation: ADN01554.1.
RefSeq	YP_003873827.1. NC_014484.1.
3D structure databases
ProteinModelPortal	E0RQQ0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADN01554; ADN01554; STHERM_c05940.
GeneID	9755848.
KEGG	sta:STHERM_c05940.
PATRIC	42520403. VBISpiThe146732_0589.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
OMA	AAEKQHT.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E0RQQ0_SPITD

Accession

Primary (citable) accession number: E0RQQ0

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 2, 2010
Last modified:	May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)