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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Paenibacillus polymyxa (strain E681)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei153 – 1531UniRule annotation
Active sitei587 – 5871UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciPPOL349520:GH6J-4201-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:PPE_04220Imported
OrganismiPaenibacillus polymyxa (strain E681)Imported
Taxonomic identifieri349520 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
ProteomesiUP000002227 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0RFW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTELTLTANK NQSNNLLRRD VRFLGNILGE VLVHQGGNEL LDIVEKIRET
60 70 80 90 100
SKSLRAGYQP ELYENFKQMV SGLDTDIRHQ VIRAFAIYFQ LVNIAEQNHR
110 120 130 140 150
IRRKRDYEHS AGEDVQPGSI ESSVQELKQE GFSAEDVSNL LKELSLELVM
160 170 180 190 200
TAHPTEATRR VILDIHKRIS EDVMLLDNPM LTLREREQVR ENLLNEVITL
210 220 230 240 250
WQTDELRDRK PTVLDEVRNG MYYFHETLFH VLPDVYQELE RCLDKYYPEQ
260 270 280 290 300
KWHIPTYLRF GSWIGGDRDG NPSVTAHVTW ETLRMQRKLA LREYQHTLKE
310 320 330 340 350
LMGYLSFSTS IVRVSDDLLA SIEEDRTHIT LKKMEVWHNE KEPYRIKLAY
360 370 380 390 400
MIAKVNNTLD ESKQGTNERY NSAEELIADL NVIDNSLRHH FADYVANTYI
410 420 430 440 450
QKMIRQVELF GFHTATLDVR QHSQEHENAM TEILSKMNIV SDYSKLSEEE
460 470 480 490 500
KINLLEKLLN EPRPITSPYL KYSDSTQECL DVYRTIYLAQ EEFGKQSITS
510 520 530 540 550
YLISMTQGAS DLLEVMVLSK EVGLFRIEKD GTVICTLQSV PLFETIDDLH
560 570 580 590 600
AAPDIMRRLM NLPVYRQSVA AMDQLQEIML GYSDSNKDGG VVTANWELRV
610 620 630 640 650
AMNSITEVVN EFGVKVKFFH GRGGALGRGG MPLNRSILAQ PPHTIGGGIK
660 670 680 690 700
ITEQGEVLSS RYSLRGIAYR SLEQATSALI TAVAYHRSGK KEVFEESWED
710 720 730 740 750
IIARISQVSL DKYQDLIFRD PDFFNFFKES TPLPEVGELN IGSRPSKRKN
760 770 780 790 800
SERFEDLRAI PWVFAWTQSR YLLPAWYAAG TGLQSFYQNN EDNLKVLQTM
810 820 830 840 850
FRDSAFFRSL IDTLQMAIAK ADLLIAEEYA GMSDNEEARQ RIFGQISAEF
860 870 880 890 900
KLTSELILKI TGQSEILDDV PVIQESIRLR NPYVDPLSYL QVQLLSELRE
910 920 930
LRDQNGDDTE MLREVLLTIN GIAAGLRNTG
Length:930
Mass (Da):106,949
Last modified:November 2, 2010 - v1
Checksum:iBAC8682A132AD690
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000154 Genomic DNA. Translation: ADM72000.1.
RefSeqiYP_003872538.1. NC_014483.1.

Genome annotation databases

EnsemblBacteriaiADM72000; ADM72000; PPE_04220.
KEGGippy:PPE_04220.
PATRICi42414216. VBIPaePol94484_4210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000154 Genomic DNA. Translation: ADM72000.1.
RefSeqiYP_003872538.1. NC_014483.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADM72000; ADM72000; PPE_04220.
KEGGippy:PPE_04220.
PATRICi42414216. VBIPaePol94484_4210.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.

Enzyme and pathway databases

BioCyciPPOL349520:GH6J-4201-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the polymyxin-producing plant-probiotic rhizobacterium Paenibacillus polymyxa E681."
    Kim J.F., Jeong H., Park S.Y., Kim S.B., Park Y.K., Choi S.K., Ryu C.M., Hur C.G., Ghim S.Y., Oh T.K., Kim J.J., Park C.S., Park S.H.
    J. Bacteriol. 192:6103-6104(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E681Imported.

Entry informationi

Entry nameiE0RFW4_PAEP6
AccessioniPrimary (citable) accession number: E0RFW4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: April 29, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.