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Protein

Thymidine kinase

Gene

PPE_02825

Organism
Paenibacillus polymyxa (strain E681)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPPOL349520:G1GMT-2800-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:PPE_02825Imported
OrganismiPaenibacillus polymyxa (strain E681)Imported
Taxonomic identifieri349520 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
Proteomesi
  • UP000002227 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi349520.PPE_02825

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107104 Bacteria
COG1435 LUCA
HOGENOMiHOG000076390
KOiK00857
OMAiCAGLDQD

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

E0RDB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYMLQRGEFA LPTGRITIIT GPMFSEKSGE LIRRCQKLIQ YGHRKVVAYK
60 70 80 90 100
PAEDNRYAED EIVSRIGYRL PAISIPRKLT DELVQRILQE TKDADVVAFD
110 120 130 140 150
EVQFFSRHIM SLVQELAYYG KHVIADGLNL DYRGKEFGYV GGLLAMADDI
160 170 180 190 200
EKLTSFCAVC GSSEAVFTQR MVNGKPSTVG PIVMIGDSEA YEPRCRNCFI

PPHKVNCD
Length:208
Mass (Da):23,466
Last modified:March 28, 2018 - v2
Checksum:i617E61DD8D01ED0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000154 Genomic DNA Translation: ADM70652.2

Genome annotation databases

EnsemblBacteriaiADM70652; ADM70652; PPE_02825
KEGGippy:PPE_02825

Similar proteinsi

Entry informationi

Entry nameiE0RDB7_PAEP6
AccessioniPrimary (citable) accession number: E0RDB7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: March 28, 2018
Last modified: April 25, 2018
This is version 43 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health