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E0RD20 (E0RD20_PAEP6) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL ADM69426.1
Ordered Locus Names:PPE_01587 EMBL ADM69426.1
OrganismPaenibacillus polymyxa (strain E681) [Complete proteome] [HAMAP] EMBL ADM69426.1
Taxonomic identifier349520 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length447 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
E0RD20 [UniParc].

Last modified November 2, 2010. Version 1.
Checksum: 4D3678D937FB68A6

FASTA44749,310
        10         20         30         40         50         60 
MSFVLYPFIS EEEKELMAKF EKFELPTEGE KITIDNGQLQ VPNHPVIPFI EGDGTGRDIW 

        70         80         90        100        110        120 
KASKRVLDAA VEKAYNGSKK IAWYEVFAGE KAFNTYGEWL PNDTLEAIRE YIVAIKGPLT 

       130        140        150        160        170        180 
TPIGGGIRSL NVALRQELDL YVCLRPVRYF NGVPSPVKRP ELVDMVIFRE NTEDIYAGIE 

       190        200        210        220        230        240 
YAEGSEDVKK VIQFLQQELG VNKIRFPETS GIGIKPVSSE GSKRLVRAAI QYAVDHGRKS 

       250        260        270        280        290        300 
VTLVHKGNIM KFTEGAFKNW GYEVAEEEFA DKVFTWAQYD VIKEKDGEDA ANAAQKAAED 

       310        320        330        340        350        360 
AGKIIIKDAI ADIALQQVLT RPSEFDVIAT LNLNGDYLSD ALAAQVGGIG IAPGANINYV 

       370        380        390        400        410        420 
TGHAIFEATH GTAPKYADKD VVNPGSVILS GVMLLEHLGW KEAADLIYKG LETSINKKIV 

       430        440 
TYDFARLMDG ATQVKCSEFA DTIISNL 

« Hide

References

[1]"Genome sequence of the polymyxin-producing plant-probiotic rhizobacterium Paenibacillus polymyxa E681."
Kim J.F., Jeong H., Park S.Y., Kim S.B., Park Y.K., Choi S.K., Ryu C.M., Hur C.G., Ghim S.Y., Oh T.K., Kim J.J., Park C.S., Park S.H.
J. Bacteriol. 192:6103-6104(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E681 EMBL ADM69426.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000154 Genomic DNA. Translation: ADM69426.1.
RefSeqYP_003869964.1. NC_014483.1.

3D structure databases

ProteinModelPortalE0RD20.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADM69426; ADM69426; PPE_01587.
GeneID9774340.
KEGGppy:PPE_01587.
PATRIC42408852. VBIPaePol94484_1569.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMAIEFNERI.

Enzyme and pathway databases

BioCycPPOL349520:GH6J-1581-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE0RD20_PAEP6
AccessionPrimary (citable) accession number: E0RD20
Entry history
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: May 14, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)