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E0IUV6

- E0IUV6_ECOLW

UniProt

E0IUV6 - E0IUV6_ECOLW

Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

puuE

Organism
Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (02 Nov 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. gamma-aminobutyric acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    AminotransferaseImported, Transferase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    4-aminobutyrate aminotransferaseImported
    Submitted name:
    4-aminobutyrate transaminaseImported (EC:2.6.1.19Imported)
    Submitted name:
    GabA aminotransferase, PLP-dependentImported
    Gene namesi
    Name:puuEImported
    Ordered Locus Names:ECW_m1398Imported, WFL_06815Imported
    ORF Names:EschWDRAFT_0182Imported
    OrganismiEscherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W)Imported
    Taxonomic identifieri566546 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000008525: Chromosome, UP000010107: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

    Phylogenomic databases

    KOiK00823.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR004632. 4NH2But_aminotransferase_bac.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
    PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E0IUV6-1 [UniParc]FASTAAdd to Basket

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    MSNNEFHQRR LSATPRGVGV MCNFFAQSAE NATLKDVEGN EYIDFAAGIA    50
    VLNTGHRHPD LVAAVEQQLQ QFTHTAYQIV PYESYVTLAE KINALAPVSG 100
    QAKTAFFTTG AEAVENAVKI ARAHTGRPGV IAFSGGFHGR TYMTMALTGK 150
    VAPYKIGFGP FPGSVYHVPY PSDLHGISTQ DSLDAIERLF KSDIEAKQVA 200
    AIIFEPVQGE GGFNVAPKEL VAAIRRLCDE HGIVMIADEV QSGFARTGKL 250
    FAMDHYVDKP DLMTMAKSLA GGMPLSGVVG NANIMDAPAP GGLGGTYAGN 300
    PLAVAAAHAV LNIIDKESLC ERANQLGQRL KNTLIDAKES VPAIAAVRGL 350
    GSMIAAEFND PQTGEPSAAI AQKIQQRALA QGLLLLTCGA YGNVIRFLYP 400
    LTIPDAQFDA AMKILQDALS D 421
    Length:421
    Mass (Da):44,729
    Last modified:November 2, 2010 - v1
    Checksum:i28E5663AC79D8E20
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002185 Genomic DNA. Translation: ADT74884.1.
    CP002967 Genomic DNA. Translation: AFH11028.1.
    AEDF01000001 Genomic DNA. Translation: EFN40153.1.
    RefSeqiYP_006124126.1. NC_017635.1.
    YP_006172814.1. NC_017664.1.

    Genome annotation databases

    EnsemblBacteriaiADT74884; ADT74884; ECW_m1398.
    AFH11028; AFH11028; WFL_06815.
    EFN40153; EFN40153; EschWDRAFT_0182.
    GeneIDi12695157.
    12753287.
    KEGGiell:WFL_06815.
    elw:ECW_m1398.
    PATRICi41588937. VBIEscCol201000_0197.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002185 Genomic DNA. Translation: ADT74884.1 .
    CP002967 Genomic DNA. Translation: AFH11028.1 .
    AEDF01000001 Genomic DNA. Translation: EFN40153.1 .
    RefSeqi YP_006124126.1. NC_017635.1.
    YP_006172814.1. NC_017664.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADT74884 ; ADT74884 ; ECW_m1398 .
    AFH11028 ; AFH11028 ; WFL_06815 .
    EFN40153 ; EFN40153 ; EschWDRAFT_0182 .
    GeneIDi 12695157.
    12753287.
    KEGGi ell:WFL_06815.
    elw:ECW_m1398.
    PATRICi 41588937. VBIEscCol201000_0197.

    Phylogenomic databases

    KOi K00823.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR004632. 4NH2But_aminotransferase_bac.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR00700. GABAtrnsam. 1 hit.
    PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: WImported.
    2. "The genome sequence of E. coli W (ATCC 9637): comparative genome analysis and an improved genome-scale reconstruction of E. coli."
      Archer C.T., Kim J.F., Jeong H., Park J.H., Vickers C.E., Lee S.Y., Nielsen L.K.
      BMC Genomics 12:9-9(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W and WImported.
    3. "Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes."
      Turner P.C., Yomano L.P., Jarboe L.R., York S.W., Baggett C.L., Moritz B.E., Zentz E.B., Shanmugam K.T., Ingram L.O.
      J. Ind. Microbiol. Biotechnol. 39:629-639(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / WImported and WImported.

    Entry informationi

    Entry nameiE0IUV6_ECOLW
    AccessioniPrimary (citable) accession number: E0IUV6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 2, 2010
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3