GP1BA

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Platelet glycoprotein Ib alpha polypeptide type 4Imported
Gene namesⁱ	Name:GP1BAImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	518 – 542	HelicalSequence analysisAdd BLAST		25

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 16	Sequence analysisAdd BLAST		16
ChainⁱPRO_5003133396	17 – 573	Sequence analysisAdd BLAST		557

Proteomic databases

PaxDbⁱ	E0D854.
PeptideAtlas More...PeptideAtlasⁱ	E0D854.
PRIDEⁱ	E0D854.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000185245.

Bgeeⁱ

ENSG00000185245.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	19 – 51	LRRNTInterPro annotationAdd BLAST		33
Domainⁱ	221 – 281	LRRCTInterPro annotationAdd BLAST		61

Keywords - Domainⁱ

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0619. Eukaryota. COG4886. LUCA.

eggNOGⁱ

KOG0619. Eukaryota.
COG4886. LUCA.

Family and domain databases

Gene3Dⁱ	3.80.10.10. 1 hit.
InterProⁱ	View protein in InterPro IPR000483. Cys-rich_flank_reg_C. IPR032675. L_dom-like. IPR001611. Leu-rich_rpt. IPR003591. Leu-rich_rpt_typical-subtyp. IPR000372. LRRNT.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13855. LRR_8. 1 hit. PF01462. LRRNT. 1 hit.
SMARTⁱ	View protein in SMART SM00369. LRR_TYP. 5 hits. SM00082. LRRCT. 1 hit. SM00013. LRRNT. 1 hit.
SUPFAMⁱ	SSF52058. SSF52058. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51450. LRR. 6 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

E0D854-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPLLLLLLLL PSPLHPHPIC EVSKVASHLE VNCDKRNLTA LPPDLPKDTT 
        60         70         80         90        100
ILHLSENLLY TFSLATLMPY TRLTQLNLDR CELTKLQVDG TLPVLGTLDL 
       110        120        130        140        150
SHNQLQSLPL LGQTLPALTV LDVSFNRLTS LPLGALRGLG ELQELYLKGN 
       160        170        180        190        200
ELKTLPPGLL TPTPKLEKLS LANNNLTELP AGLLNGLENL DTLLLQENSL 
       210        220        230        240        250
YTIPKGFFGS HLLPFAFLHG NPWLCNCEIL YFRRWLQDNA ENVYVWKQGV 
       260        270        280        290        300
DVKAMTSNVA SVQCDNSDKF PVYKYPGKGC PTLGDEGDTD LYDYYPEEDT 
       310        320        330        340        350
EGDKVRATRT VVKFPTKAHT TPWGLFYSWS TASLDSQMPS SLHPTQESTK 
       360        370        380        390        400
EQTTFPPRWT PNFTLHMESI TFSKTPKSTT EPTPSPTTSE PVPEPAPNMT 
       410        420        430        440        450
TLEPTPSPTT PEPTSEPAPS PTTPEPTSEP APSPTTPEPT PIPTIATSPT 
       460        470        480        490        500
ILVSATSLIT PKSTFLTTTK PVSLLESTKK TIPELDQPPK LRGVLQGHLE 
       510        520        530        540        550
SSRNDPFLHP DFCCLLPLGF YVLGLFWLLF ASVVLILLLS WVGHVKPQAL 
       560        570 
DSGQGAALTT ATQTTHLELQ RGR

Length:573

Mass (Da):62,976

Last modified:November 2, 2010 - v1

Checksum:ⁱ5A97E299B9ABC8C1

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB576654 Genomic DNA. Translation: BAJ15420.1.
UniGeneⁱ	Hs.1472.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB576654 Genomic DNA. Translation: BAJ15420.1.
UniGeneⁱ	Hs.1472.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PaxDbⁱ	E0D854.
PeptideAtlas More...PeptideAtlasⁱ	E0D854.
PRIDEⁱ	E0D854.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

eggNOGⁱ	KOG0619. Eukaryota. COG4886. LUCA.

eggNOGⁱ

KOG0619. Eukaryota.
COG4886. LUCA.

Gene expression databases

Bgeeⁱ	ENSG00000185245.

Bgeeⁱ

ENSG00000185245.

Family and domain databases

Gene3Dⁱ	3.80.10.10. 1 hit.
InterProⁱ	View protein in InterPro IPR000483. Cys-rich_flank_reg_C. IPR032675. L_dom-like. IPR001611. Leu-rich_rpt. IPR003591. Leu-rich_rpt_typical-subtyp. IPR000372. LRRNT.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13855. LRR_8. 1 hit. PF01462. LRRNT. 1 hit.
SMARTⁱ	View protein in SMART SM00369. LRR_TYP. 5 hits. SM00082. LRRCT. 1 hit. SM00013. LRRNT. 1 hit.
SUPFAMⁱ	SSF52058. SSF52058. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51450. LRR. 6 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	E0D854_HUMAN
Accessionⁱ	E0D854Primary (citable) accession number: E0D854
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 2, 2010
	Last sequence update:	November 2, 2010
	Last modified:	July 5, 2017
	This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - E0D854 (E0D854_HUMAN)

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Platelet glycoprotein Ib alpha polypeptide type 4

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Names & Taxonomyⁱ

Subcellular locationⁱ

Topology

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Molecule processing

Proteomic databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - E0D854 (E0D854_HUMAN)

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Platelet glycoprotein Ib alpha polypeptide type 4

GP1BA

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ