Cct5

Functionⁱ

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-KW
beta-tubulin binding Source: Ensembl
G-protein beta-subunit binding Source: Ensembl
mRNA 3'-UTR binding Source: Ensembl
mRNA 5'-UTR binding Source: Ensembl
unfolded protein binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

binding of sperm to zona pellucida Source: Ensembl
positive regulation of establishment of protein localization to telomere Source: Ensembl
positive regulation of protein localization to Cajal body Source: Ensembl
positive regulation of telomerase RNA localization to Cajal body Source: Ensembl
positive regulation of telomere maintenance via telomerase Source: Ensembl
protein folding Source: InterPro
protein stabilization Source: Ensembl
response to virus Source: Ensembl
toxin transport Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	ChaperoneUniRule annotation
Ligand	ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: T-complex protein 1 subunit epsilonImported
Gene namesⁱ	Name:Cct5Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 15

Organism-specific databases

MGIⁱ	MGI:107185. Cct5.

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	E0CZA1.
PeptideAtlas More...PeptideAtlasⁱ	E0CZA1.
PRIDEⁱ	E0CZA1.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000022234.
ExpressionAtlasⁱ	E0CZA1. baseline and differential.

Interactionⁱ

GO - Molecular functionⁱ

beta-tubulin binding Source: Ensembl
G-protein beta-subunit binding Source: Ensembl
unfolded protein binding Source: InterPro

View the complete GO annotation on QuickGO ...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG0357. Eukaryota. COG0459. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074988.

Family and domain databases

Gene3Dⁱ	1.10.560.10. 1 hit. 3.30.260.10. 1 hit. 3.50.7.10. 1 hit.
InterProⁱ	View protein in InterPro IPR012718. Chap_CCT_epsi. IPR017998. Chaperone_TCP-1. IPR002194. Chaperonin_TCP-1_CS. IPR002423. Cpn60/TCP-1. IPR027409. GroEL-like_apical_dom_sf. IPR027413. GROEL-like_equatorial_sf. IPR027410. TCP-1-like_intermed_sf.
PANTHERⁱ	PTHR11353. PTHR11353. 1 hit. PTHR11353:SF178. PTHR11353:SF178. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00118. Cpn60_TCP1. 1 hit.
PRINTSⁱ	PR00304. TCOMPLEXTCP1.
SUPFAMⁱ	SSF48592. SSF48592. 1 hit. SSF54849. SSF54849. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00750. TCP1_1. 1 hit. PS00751. TCP1_2. 1 hit. PS00995. TCP1_3. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

E0CZA1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAAKAVANTM RTSLGPNGLD KMMVDKDGDV TITNDGATIL SMMDVDHQIA 
        60         70         80         90        100
KLMVELSKSQ DDEIGDGTTG VVVLAGALLE EAEQLLDRGI HPIRIADGYE 
       110        120        130        140        150
QAARIAIQHL DKISDKVLVD INNPEPLIQT AKTTLGSKVI NSCHRQMAEI 
       160        170        180        190 
AVNAVLTVAD MERRDVDFEL IKVEGKVGGR LEDTKLIKGV IVDKDFSHP

Length:199

Mass (Da):21,526

Last modified:October 5, 2010 - v1

Checksum:ⁱ60787076B6AB30FF

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	199	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC137842 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC137842 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENSMUST00000161266; ENSMUSP00000125566; ENSMUSG00000022234.

Ensemblⁱ

ENSMUST00000161266; ENSMUSP00000125566; ENSMUSG00000022234.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
E0CZA1	P80316 A0A0P6CE00 UPI0003D6F3C1	Mus musculus (Mouse) Daphnia magna	541	UniRef100_P80316	Cluster: T-complex protein 1 subunit epsilon	4

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
E0CZA1	P80316 A0A0P6CE00 UPI0003D6F3C1 UPI000BB46E0B UPI000BB48CC7 L5LJ04 L8IAU0 UPI00078773AC UPI00018B6A8C UPI00042BDAC2 +83	Mus musculus (Mouse) Daphnia magna Enhydra lutris kenyoni Myotis davidii (David's myotis) Bos mutus (wild yak) Rousettus aegyptiacus (Egyptian rousette) (Egyptian fruit bat) Orcinus orca (Killer whale) Panthera tigris altaica (Siberian tiger) Panthera pardus (Leopard) (Felis pardus) Physeter catodon (Sperm whale) (Physeter macrocephalus) And more	541	UniRef90_P80316	Cluster: T-complex protein 1 subunit epsilon	94

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
E0CZA1	P48643 Q4R6V2 V9HW37 H2QQM7 A0A1D5Q8I4 G3SG70 A0A2J8SHI4 A0A2K6L6Z7 A0A2K6CZM5 A0A2K5LK27 +1024	Homo sapiens (Human) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Pan troglodytes (Chimpanzee) Macaca mulatta (Rhesus macaque) Gorilla gorilla gorilla (Western lowland gorilla) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) Macaca nemestrina (Pig-tailed macaque) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) And more	541	UniRef50_P48643	Cluster: T-complex protein 1 subunit epsilon	1,035

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC137842 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC137842 Genomic DNA. No translation available.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	E0CZA1.
PeptideAtlas More...PeptideAtlasⁱ	E0CZA1.
PRIDEⁱ	E0CZA1.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000161266; ENSMUSP00000125566; ENSMUSG00000022234.

Ensemblⁱ

ENSMUST00000161266; ENSMUSP00000125566; ENSMUSG00000022234.

Organism-specific databases

MGIⁱ	MGI:107185. Cct5.

Phylogenomic databases

eggNOGⁱ	KOG0357. Eukaryota. COG0459. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074988.

Miscellaneous databases

ChiTaRSⁱ	Cct5. mouse.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000022234.
ExpressionAtlasⁱ	E0CZA1. baseline and differential.

Family and domain databases

Gene3Dⁱ	1.10.560.10. 1 hit. 3.30.260.10. 1 hit. 3.50.7.10. 1 hit.
InterProⁱ	View protein in InterPro IPR012718. Chap_CCT_epsi. IPR017998. Chaperone_TCP-1. IPR002194. Chaperonin_TCP-1_CS. IPR002423. Cpn60/TCP-1. IPR027409. GroEL-like_apical_dom_sf. IPR027413. GROEL-like_equatorial_sf. IPR027410. TCP-1-like_intermed_sf.
PANTHERⁱ	PTHR11353. PTHR11353. 1 hit. PTHR11353:SF178. PTHR11353:SF178. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00118. Cpn60_TCP1. 1 hit.
PRINTSⁱ	PR00304. TCOMPLEXTCP1.
SUPFAMⁱ	SSF48592. SSF48592. 1 hit. SSF54849. SSF54849. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00750. TCP1_1. 1 hit. PS00751. TCP1_2. 1 hit. PS00995. TCP1_3. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	E0CZA1_MOUSE
Accessionⁱ	E0CZA1Primary (citable) accession number: E0CZA1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 5, 2010
	Last sequence update:	October 5, 2010
	Last modified:	March 28, 2018
	This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - E0CZA1 (E0CZA1_MOUSE)

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T-complex protein 1 subunit epsilon

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytoskeleton

Cytosol

Nucleus

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ