UniProtKB - E0CZA1 (E0CZA1_MOUSE)
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Protein
Submitted name:
T-complex protein 1 subunit epsilon
Gene
Cct5
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- beta-tubulin binding Source: Ensembl
- G-protein beta-subunit binding Source: Ensembl
- mRNA 3'-UTR binding Source: Ensembl
- mRNA 5'-UTR binding Source: Ensembl
- unfolded protein binding Source: InterPro
GO - Biological processi
- binding of sperm to zona pellucida Source: Ensembl
- positive regulation of establishment of protein localization to telomere Source: Ensembl
- positive regulation of protein localization to Cajal body Source: Ensembl
- positive regulation of telomerase RNA localization to Cajal body Source: Ensembl
- positive regulation of telomere maintenance via telomerase Source: Ensembl
- protein folding Source: InterPro
- protein stabilization Source: Ensembl
- response to virus Source: Ensembl
- toxin transport Source: Ensembl
Keywordsi
Molecular function | ChaperoneUniRule annotation |
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: T-complex protein 1 subunit epsilonImported |
Gene namesi | Name:Cct5Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:107185. Cct5. |
Subcellular locationi
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000022234. |
ExpressionAtlasi | E0CZA1. baseline and differential. |
Interactioni
GO - Molecular functioni
- beta-tubulin binding Source: Ensembl
- G-protein beta-subunit binding Source: Ensembl
- unfolded protein binding Source: InterPro
Family & Domainsi
Sequence similaritiesi
Belongs to the TCP-1 chaperonin family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0357. Eukaryota. COG0459. LUCA. |
GeneTreei | ENSGT00550000074988. |
Family and domain databases
Gene3Di | 1.10.560.10. 1 hit. 3.30.260.10. 1 hit. 3.50.7.10. 1 hit. |
InterProi | View protein in InterPro IPR012718. Chap_CCT_epsi. IPR017998. Chaperone_TCP-1. IPR002194. Chaperonin_TCP-1_CS. IPR002423. Cpn60/TCP-1. IPR027409. GroEL-like_apical_dom_sf. IPR027413. GROEL-like_equatorial_sf. IPR027410. TCP-1-like_intermed_sf. |
PANTHERi | PTHR11353. PTHR11353. 1 hit. PTHR11353:SF178. PTHR11353:SF178. 1 hit. |
Pfami | View protein in Pfam PF00118. Cpn60_TCP1. 1 hit. |
PRINTSi | PR00304. TCOMPLEXTCP1. |
SUPFAMi | SSF48592. SSF48592. 1 hit. SSF54849. SSF54849. 1 hit. |
PROSITEi | View protein in PROSITE PS00750. TCP1_1. 1 hit. PS00751. TCP1_2. 1 hit. PS00995. TCP1_3. 1 hit. |
i Sequence
Sequence statusi: Fragment.
E0CZA1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAKAVANTM RTSLGPNGLD KMMVDKDGDV TITNDGATIL SMMDVDHQIA
60 70 80 90 100
KLMVELSKSQ DDEIGDGTTG VVVLAGALLE EAEQLLDRGI HPIRIADGYE
110 120 130 140 150
QAARIAIQHL DKISDKVLVD INNPEPLIQT AKTTLGSKVI NSCHRQMAEI
160 170 180 190
AVNAVLTVAD MERRDVDFEL IKVEGKVGGR LEDTKLIKGV IVDKDFSHP
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 199 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC137842 Genomic DNA. No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000161266; ENSMUSP00000125566; ENSMUSG00000022234. |
Similar proteinsi
Entry informationi
Entry namei | E0CZA1_MOUSE | |
Accessioni | E0CZA1Primary (citable) accession number: E0CZA1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 5, 2010 |
Last sequence update: | October 5, 2010 | |
Last modified: | March 28, 2018 | |
This is version 59 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |