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E0CY49

- E0CY49_MOUSE

UniProt

E0CY49 - E0CY49_MOUSE

Protein
Submitted name:

Argininosuccinate lyase

Gene

Asl

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (05 Oct 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. argininosuccinate lyase activity Source: InterPro

    GO - Biological processi

    1. ammonia assimilation cycle Source: MGI
    2. arginine biosynthetic process via ornithine Source: InterPro
    3. cellular amino acid metabolic process Source: MGI
    4. locomotory behavior Source: MGI
    5. post-embryonic development Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Argininosuccinate lyaseImported
    Gene namesi
    Name:AslImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 5

    Organism-specific databases

    MGIiMGI:88084. Asl.

    Expressioni

    Gene expression databases

    ArrayExpressiE0CY49.
    BgeeiE0CY49.

    Structurei

    3D structure databases

    ProteinModelPortaliE0CY49.
    SMRiE0CY49. Positions 6-262.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000014045.

    Family and domain databases

    Gene3Di1.10.275.10. 1 hit.
    InterProiIPR009049. Argininosuccinate_lyase.
    IPR024083. Fumarase/histidase_N.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    [Graphical view]
    PANTHERiPTHR11444. PTHR11444. 1 hit.
    PTHR11444:SF3. PTHR11444:SF3. 1 hit.
    PfamiPF00206. Lyase_1. 1 hit.
    [Graphical view]
    PRINTSiPR00149. FUMRATELYASE.
    SUPFAMiSSF48557. SSF48557. 1 hit.
    TIGRFAMsiTIGR00838. argH. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    E0CY49-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASESGKLWG GRFVGAVDPI MEKFNSSISY DRHLWNVDVQ GSKAYSRGLE    50
    KAGLLTKAEM QQILQGLDKV AEEWAQGTFK LHPNDEDIHT ANERRLKELI 100
    GEAAGKLHTG RSRNDQVVTD LRLWMRQTCS KLSALLRVLI GTMVDRAEAE 150
    RDVLFPGYTH LQRAQPIRWS HWILSHAVAL TRDSERLLEV QKRINVLPLG 200
    SGAIAGNPLG VDRELLRAEL NFGAITLNSM DATSERDFVA EFLFWASLCM 250
    THLSRMAEDL IL 262
    Length:262
    Mass (Da):29,478
    Last modified:October 5, 2010 - v1
    Checksum:iE157C149EB603019
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei262 – 2621Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161345 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000161640; ENSMUSP00000124487; ENSMUSG00000025533.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161345 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E0CY49.
    SMRi E0CY49. Positions 6-262.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000161640 ; ENSMUSP00000124487 ; ENSMUSG00000025533 .

    Organism-specific databases

    MGIi MGI:88084. Asl.

    Phylogenomic databases

    GeneTreei ENSGT00390000014045.

    Miscellaneous databases

    NextBioi 35553186.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E0CY49.
    Bgeei E0CY49.

    Family and domain databases

    Gene3Di 1.10.275.10. 1 hit.
    InterProi IPR009049. Argininosuccinate_lyase.
    IPR024083. Fumarase/histidase_N.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    [Graphical view ]
    PANTHERi PTHR11444. PTHR11444. 1 hit.
    PTHR11444:SF3. PTHR11444:SF3. 1 hit.
    Pfami PF00206. Lyase_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00149. FUMRATELYASE.
    SUPFAMi SSF48557. SSF48557. 1 hit.
    TIGRFAMsi TIGR00838. argH. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    3. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiE0CY49_MOUSE
    AccessioniPrimary (citable) accession number: E0CY49
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 5, 2010
    Last sequence update: October 5, 2010
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3