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E0CXM2

- E0CXM2_MOUSE

UniProt

E0CXM2 - E0CXM2_MOUSE

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Protein
Submitted name:

Argininosuccinate lyase

Gene

Asl

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. argininosuccinate lyase activity Source: InterPro

GO - Biological processi

  1. ammonia assimilation cycle Source: MGI
  2. arginine biosynthetic process via ornithine Source: InterPro
  3. cellular amino acid metabolic process Source: MGI
  4. locomotory behavior Source: MGI
  5. post-embryonic development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Argininosuccinate lyaseImported
Gene namesi
Name:AslImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 5

Organism-specific databases

MGIiMGI:88084. Asl.

Expressioni

Gene expression databases

BgeeiE0CXM2.
ExpressionAtlasiE0CXM2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE0CXM2.
SMRiE0CXM2. Positions 6-437.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000014045.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
HAMAPiMF_00006. Arg_succ_lyase.
InterProiIPR029419. Arg_succ_lyase_C.
IPR009049. Argininosuccinate_lyase.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PTHR11444:SF3. PTHR11444:SF3. 1 hit.
PfamiPF14698. ASL_C2. 1 hit.
PF00206. Lyase_1. 2 hits.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00838. argH. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0CXM2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASESGKLWG GRFVGAVDPI MEKFNSSISY DRHLWNVDVQ GSKAYSRGLE
60 70 80 90 100
KAGLLTKAEM QQILQGLDKV AEEWAQGTFK LHPNDEDIHT ANERRLKELI
110 120 130 140 150
GEAAGKLHTG RSRNDQVVTD LRLWMRQTCS KLSALLRVLI GTMVDRAEAE
160 170 180 190 200
RDVLFPGYTH LQRAQPIRWS HWILSGAIAG NPLGVDRELL RAELNFGAIT
210 220 230 240 250
LNSMDATSER DFVAEFLFWA SLCMTHLSRM AEDLILYGTK EFSFVQLSDA
260 270 280 290 300
YSTGSSLMPQ KKNPDSLELI RSKAGRVFGR CAGLLMTLKG LPSTYNKDLQ
310 320 330 340 350
EDKEAVFEVS DTMIAVLQVA TGVISTLQIH RENMKQALSP DMLATDLAYY
360 370 380 390 400
LVRKGMPFRQ AHEASGKAVF MAETKGVALN LLSLQELQTI SPLFSGDVSH
410 420 430
VWDYSHSVEQ YSALGGTAKS SVEWQIRQVR ALLQAQEP
Length:438
Mass (Da):48,842
Last modified:October 5, 2010 - v1
Checksum:i35FE8016E1BE5D70
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC161345 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000160208; ENSMUSP00000125194; ENSMUSG00000025533.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC161345 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E0CXM2.
SMRi E0CXM2. Positions 6-437.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000160208 ; ENSMUSP00000125194 ; ENSMUSG00000025533 .

Organism-specific databases

MGIi MGI:88084. Asl.

Phylogenomic databases

GeneTreei ENSGT00390000014045.

Miscellaneous databases

NextBioi 35553025.
SOURCEi Search...

Gene expression databases

Bgeei E0CXM2.
ExpressionAtlasi E0CXM2. baseline and differential.

Family and domain databases

Gene3Di 1.10.275.10. 1 hit.
HAMAPi MF_00006. Arg_succ_lyase.
InterProi IPR029419. Arg_succ_lyase_C.
IPR009049. Argininosuccinate_lyase.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view ]
PANTHERi PTHR11444. PTHR11444. 1 hit.
PTHR11444:SF3. PTHR11444:SF3. 1 hit.
Pfami PF14698. ASL_C2. 1 hit.
PF00206. Lyase_1. 2 hits.
[Graphical view ]
PRINTSi PR00149. FUMRATELYASE.
SUPFAMi SSF48557. SSF48557. 1 hit.
TIGRFAMsi TIGR00838. argH. 1 hit.
PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  3. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE0CXM2_MOUSE
AccessioniPrimary (citable) accession number: E0CXM2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: October 29, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3