Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E0CXM2

- E0CXM2_MOUSE

UniProt

E0CXM2 - E0CXM2_MOUSE

Protein
Submitted name:

Argininosuccinate lyase

Gene

Asl

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (05 Oct 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. argininosuccinate lyase activity Source: InterPro

    GO - Biological processi

    1. ammonia assimilation cycle Source: MGI
    2. arginine biosynthetic process via ornithine Source: InterPro
    3. cellular amino acid metabolic process Source: MGI
    4. locomotory behavior Source: MGI
    5. post-embryonic development Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Argininosuccinate lyaseImported
    Gene namesi
    Name:AslImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 5

    Organism-specific databases

    MGIiMGI:88084. Asl.

    Expressioni

    Gene expression databases

    ArrayExpressiE0CXM2.
    BgeeiE0CXM2.

    Structurei

    3D structure databases

    ProteinModelPortaliE0CXM2.
    SMRiE0CXM2. Positions 6-437.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000014045.

    Family and domain databases

    Gene3Di1.10.275.10. 1 hit.
    HAMAPiMF_00006. Arg_succ_lyase.
    InterProiIPR029419. Arg_succ_lyase_C.
    IPR009049. Argininosuccinate_lyase.
    IPR024083. Fumarase/histidase_N.
    IPR020557. Fumarate_lyase_CS.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    [Graphical view]
    PANTHERiPTHR11444. PTHR11444. 1 hit.
    PTHR11444:SF3. PTHR11444:SF3. 1 hit.
    PfamiPF14698. ASL_C2. 1 hit.
    PF00206. Lyase_1. 2 hits.
    [Graphical view]
    PRINTSiPR00149. FUMRATELYASE.
    SUPFAMiSSF48557. SSF48557. 1 hit.
    TIGRFAMsiTIGR00838. argH. 1 hit.
    PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E0CXM2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASESGKLWG GRFVGAVDPI MEKFNSSISY DRHLWNVDVQ GSKAYSRGLE    50
    KAGLLTKAEM QQILQGLDKV AEEWAQGTFK LHPNDEDIHT ANERRLKELI 100
    GEAAGKLHTG RSRNDQVVTD LRLWMRQTCS KLSALLRVLI GTMVDRAEAE 150
    RDVLFPGYTH LQRAQPIRWS HWILSGAIAG NPLGVDRELL RAELNFGAIT 200
    LNSMDATSER DFVAEFLFWA SLCMTHLSRM AEDLILYGTK EFSFVQLSDA 250
    YSTGSSLMPQ KKNPDSLELI RSKAGRVFGR CAGLLMTLKG LPSTYNKDLQ 300
    EDKEAVFEVS DTMIAVLQVA TGVISTLQIH RENMKQALSP DMLATDLAYY 350
    LVRKGMPFRQ AHEASGKAVF MAETKGVALN LLSLQELQTI SPLFSGDVSH 400
    VWDYSHSVEQ YSALGGTAKS SVEWQIRQVR ALLQAQEP 438
    Length:438
    Mass (Da):48,842
    Last modified:October 5, 2010 - v1
    Checksum:i35FE8016E1BE5D70
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161345 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000160208; ENSMUSP00000125194; ENSMUSG00000025533.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161345 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E0CXM2.
    SMRi E0CXM2. Positions 6-437.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000160208 ; ENSMUSP00000125194 ; ENSMUSG00000025533 .

    Organism-specific databases

    MGIi MGI:88084. Asl.

    Phylogenomic databases

    GeneTreei ENSGT00390000014045.

    Miscellaneous databases

    NextBioi 35553025.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E0CXM2.
    Bgeei E0CXM2.

    Family and domain databases

    Gene3Di 1.10.275.10. 1 hit.
    HAMAPi MF_00006. Arg_succ_lyase.
    InterProi IPR029419. Arg_succ_lyase_C.
    IPR009049. Argininosuccinate_lyase.
    IPR024083. Fumarase/histidase_N.
    IPR020557. Fumarate_lyase_CS.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    [Graphical view ]
    PANTHERi PTHR11444. PTHR11444. 1 hit.
    PTHR11444:SF3. PTHR11444:SF3. 1 hit.
    Pfami PF14698. ASL_C2. 1 hit.
    PF00206. Lyase_1. 2 hits.
    [Graphical view ]
    PRINTSi PR00149. FUMRATELYASE.
    SUPFAMi SSF48557. SSF48557. 1 hit.
    TIGRFAMsi TIGR00838. argH. 1 hit.
    PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    3. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiE0CXM2_MOUSE
    AccessioniPrimary (citable) accession number: E0CXM2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 5, 2010
    Last sequence update: October 5, 2010
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3