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Protein

Proteasome endopeptidase complex

Gene

Psma6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Threonine proteasePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome endopeptidase complexPROSITE-ProRule annotation (EC:3.4.25.1PROSITE-ProRule annotation)
Gene namesi
Name:Psma6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1347006 Psma6

Subcellular locationi

Keywords - Cellular componenti

CytoplasmPROSITE-ProRule annotation, ProteasomePROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

MaxQBiE0CXB1
PeptideAtlasiE0CXB1
PRIDEiE0CXB1

Expressioni

Gene expression databases

BgeeiENSMUSG00000021024
ExpressionAtlasiE0CXB1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE0CXB1
SMRiE0CXB1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1A family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0182 Eukaryota
ENOG410XR7X LUCA
GeneTreeiENSGT00550000074807

Family and domain databases

CDDicd03754 proteasome_alpha_type_6, 1 hit
Gene3Di3.60.20.10, 1 hit
InterProiView protein in InterPro
IPR029055 Ntn_hydrolases_N
IPR023332 Proteasome_alpha-type
IPR001353 Proteasome_sua/b
IPR034642 Proteasome_subunit_alpha6
PANTHERiPTHR11599:SF11 PTHR11599:SF11, 1 hit
PfamiView protein in Pfam
PF00227 Proteasome, 1 hit
SUPFAMiSSF56235 SSF56235, 1 hit
PROSITEiView protein in PROSITE
PS51475 PROTEASOME_ALPHA_2, 1 hit

Sequencei

Sequence statusi: Complete.

E0CXB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASLRKKYAF KAINQGGLTS VAVRGKDCAV IVTQKKVPDK LLDSSTVTHL
60 70 80 90 100
FKITESIGCV MTGMTADSRS QVQRARYEAA NWKYKYGYEI PVDMLCKRIA
110 120 130 140 150
DISQVYTQNA EMRPLGCCMI LIGIDEEQGP QVYKCDPAGY YCGFKATAAG
160 170 180 190 200
VKQTESTSFL EKKVKKKFDW TFEQTVETAI TCLSTVLSID FKPSEIEVGV
210 220
VTVENPKFRI LTEAEIDAHL VALAERD
Length:227
Mass (Da):25,264
Last modified:October 5, 2010 - v1
Checksum:iED770AE759A8172F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159636 Genomic DNA No translation available.
RefSeqiNP_001297512.1, NM_001310583.1
UniGeneiMm.30210

Genome annotation databases

EnsembliENSMUST00000163070; ENSMUSP00000124781; ENSMUSG00000021024
GeneIDi26443

Similar proteinsi

Entry informationi

Entry nameiE0CXB1_MOUSE
AccessioniPrimary (citable) accession number: E0CXB1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: March 28, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health