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Protein
Submitted name:

Vitronectin

Gene

VTN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
VitronectinImported
Gene namesi
Name:VTNImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 478459Sequence analysisPRO_5003133002Add
BLAST

Proteomic databases

PaxDbiD9ZGG2.
PRIDEiD9ZGG2.

Expressioni

Gene expression databases

BgeeiD9ZGG2.
ExpressionAtlasiD9ZGG2. baseline and differential.
GenevisibleiD9ZGG2. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000226218.

Structurei

3D structure databases

ProteinModelPortaliD9ZGG2.
SMRiD9ZGG2. Positions 21-60, 155-343.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 6344SMB (somatomedin-B)InterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1565. Eukaryota.
ENOG410XQ5D. LUCA.
KOiK06251.
OMAiLFWGRSS.
PhylomeDBiD9ZGG2.

Family and domain databases

Gene3Di2.110.10.10. 3 hits.
InterProiIPR000585. Hemopexin-like_dom.
IPR018487. Hemopexin-like_repeat.
IPR018486. Hemopexin_CS.
IPR020436. Somatomedin_B_chordata.
IPR001212. Somatomedin_B_dom.
[Graphical view]
PfamiPF00045. Hemopexin. 4 hits.
PF01033. Somatomedin_B. 1 hit.
[Graphical view]
PRINTSiPR00022. SOMATOMEDINB.
SMARTiSM00120. HX. 4 hits.
SM00201. SO. 1 hit.
[Graphical view]
SUPFAMiSSF50923. SSF50923. 3 hits.
SSF90188. SSF90188. 1 hit.
PROSITEiPS00024. HEMOPEXIN. 2 hits.
PS51642. HEMOPEXIN_2. 4 hits.
PS00524. SMB_1. 1 hit.
PS50958. SMB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D9ZGG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPLRPLLIL ALLAWVALAD QESCKGRCTE GFNVDKKCQC DELCSYYQSC
60 70 80 90 100
CTDYTAECKP QVTRGDVFTM PEDEYTVYDD GEEKNNATVH EQVGGPSLTS
110 120 130 140 150
DLQAQSKGNP EQTPVLKPEE EAPAPEVGAS KPEGIDSRPE TLHPGRPQPP
160 170 180 190 200
AEEELCSGKP FDAFTDLKNG SLFAFRGQYC YELDEKAVRP GYPKLIRDVW
210 220 230 240 250
GIEGPIDAAF TRINCQGKTY LFKGSQYWRF EDGVLDPDYP RNISDGFDGI
260 270 280 290 300
PDNVDAALAL PAHSYSGRER VYFFKGKQYW EYQFQHQPSQ EECEGSSLSA
310 320 330 340 350
VFEHFAMMQR DSWEDIFELL FWGRTSAGTR QPQFISRDWH GVPGQVDAAM
360 370 380 390 400
AGRIYISGMA PRPSLAKKQR FRHRNRKGYR SQRGHSRGRN QNSRRPSRAT
410 420 430 440 450
WLSLFSSEES NLGANNYDDY RMDWLVPATC EPIQSVFFFS GDKYYRVNLR
460 470
TRRVDTVDPP YPRSIAQYWL GCPAPGHL
Length:478
Mass (Da):54,306
Last modified:October 5, 2010 - v1
Checksum:i0D6DB5591CBFEF45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM015600 Genomic DNA. Translation: ADL14521.1.
RefSeqiNP_000629.3. NM_000638.3.
UniGeneiHs.2257.

Genome annotation databases

GeneIDi7448.
KEGGihsa:7448.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM015600 Genomic DNA. Translation: ADL14521.1.
RefSeqiNP_000629.3. NM_000638.3.
UniGeneiHs.2257.

3D structure databases

ProteinModelPortaliD9ZGG2.
SMRiD9ZGG2. Positions 21-60, 155-343.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000226218.

Proteomic databases

PaxDbiD9ZGG2.
PRIDEiD9ZGG2.

Protocols and materials databases

DNASUi7448.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7448.
KEGGihsa:7448.

Organism-specific databases

CTDi7448.

Phylogenomic databases

eggNOGiKOG1565. Eukaryota.
ENOG410XQ5D. LUCA.
KOiK06251.
OMAiLFWGRSS.
PhylomeDBiD9ZGG2.

Miscellaneous databases

GenomeRNAii7448.
NextBioi29166.

Gene expression databases

BgeeiD9ZGG2.
ExpressionAtlasiD9ZGG2. baseline and differential.
GenevisibleiD9ZGG2. HS.

Family and domain databases

Gene3Di2.110.10.10. 3 hits.
InterProiIPR000585. Hemopexin-like_dom.
IPR018487. Hemopexin-like_repeat.
IPR018486. Hemopexin_CS.
IPR020436. Somatomedin_B_chordata.
IPR001212. Somatomedin_B_dom.
[Graphical view]
PfamiPF00045. Hemopexin. 4 hits.
PF01033. Somatomedin_B. 1 hit.
[Graphical view]
PRINTSiPR00022. SOMATOMEDINB.
SMARTiSM00120. HX. 4 hits.
SM00201. SO. 1 hit.
[Graphical view]
SUPFAMiSSF50923. SSF50923. 3 hits.
SSF90188. SSF90188. 1 hit.
PROSITEiPS00024. HEMOPEXIN. 2 hits.
PS51642. HEMOPEXIN_2. 4 hits.
PS00524. SMB_1. 1 hit.
PS50958. SMB_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiD9ZGG2_HUMAN
AccessioniPrimary (citable) accession number: D9ZGG2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 11, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.