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Protein
Submitted name:

T-box 1

Gene

TBX1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
T-box 1Imported
Gene namesi
Name:TBX1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiD9ZGG0.

Expressioni

Gene expression databases

BgeeiD9ZGG0.
ExpressionAtlasiD9ZGG0. baseline and differential.
GenevisibleiD9ZGG0. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000331791.

Structurei

3D structure databases

ProteinModelPortaliD9ZGG0.
SMRiD9ZGG0. Positions 109-296.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains T-box DNA-binding domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118897.
OMAiTYEHYLG.
PhylomeDBiD9ZGG0.

Family and domain databases

Gene3Di2.60.40.820. 1 hit.
InterProiIPR008967. p53-like_TF_DNA-bd.
IPR001699. TF_T-box.
IPR018186. TF_T-box_CS.
[Graphical view]
PANTHERiPTHR11267. PTHR11267. 1 hit.
PfamiPF00907. T-box. 1 hit.
[Graphical view]
PRINTSiPR00937. TBOX.
SMARTiSM00425. TBOX. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS01283. TBOX_1. 1 hit.
PS01264. TBOX_2. 1 hit.
PS50252. TBOX_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D9ZGG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHFSTVTRDM EAFTASSLSS LGAAGGFPGA ASPGADPYGP REPPPPPPRY
60 70 80 90 100
DPCAAAAPGA PGPPPPPHAY PFAPAAGAAT SAAAEPEGPG ASCAAAAKAP
110 120 130 140 150
VKKNAKVAGV SVQLEMKALW DEFNQLGTEM IVTKAGRRMF PTFQVKLFGM
160 170 180 190 200
DPMADYMLLM DFVPVDDKRY RYAFHSSSWL VAGKADPATP GRVHYHPDSP
210 220 230 240 250
AKGAQWMKQI VSFDKLKLTN NLLDDNGHII LNSMHRYQPR FHVVYVDPRK
260 270 280 290 300
DSEKYAEENF KTFVFEETRF TAVTAYQNHR ITQLKIASNP FAKGFRDCDP
310 320 330 340 350
EDWPRNHRPG ALPLMSAFAR SRNPVASPTQ PSGTEKDAAE ARREFQRDAG
360 370 380 390 400
GPAVLGDPAH PPQLLARVLS PSLPGAGGAG GLVPLPGAPG GRPSPPNPEL
410 420 430 440 450
RLEAPGASEP LHHHPYKYPA AAYDHYLGAK SRPAPYPLPG LRGHGYHPHA
460 470 480 490
HPHHHHHPVS PAAAAAAAAA AAAAAANMYS SAGAAPPGSY DYCPR
Length:495
Mass (Da):52,666
Last modified:October 5, 2010 - v1
Checksum:iFB0C150FEA6155FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM015598 Genomic DNA. Translation: ADL14519.1.
RefSeqiNP_542378.1. NM_080647.1.
XP_006724375.1. XM_006724312.1.
UniGeneiHs.173984.

Genome annotation databases

GeneIDi6899.
UCSCiuc002zqa.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM015598 Genomic DNA. Translation: ADL14519.1.
RefSeqiNP_542378.1. NM_080647.1.
XP_006724375.1. XM_006724312.1.
UniGeneiHs.173984.

3D structure databases

ProteinModelPortaliD9ZGG0.
SMRiD9ZGG0. Positions 109-296.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000331791.

Proteomic databases

PRIDEiD9ZGG0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6899.
UCSCiuc002zqa.1. human.

Organism-specific databases

CTDi6899.

Phylogenomic databases

GeneTreeiENSGT00760000118897.
OMAiTYEHYLG.
PhylomeDBiD9ZGG0.

Miscellaneous databases

ChiTaRSiTBX1. human.
GenomeRNAii6899.
NextBioi26967.

Gene expression databases

BgeeiD9ZGG0.
ExpressionAtlasiD9ZGG0. baseline and differential.
GenevisibleiD9ZGG0. HS.

Family and domain databases

Gene3Di2.60.40.820. 1 hit.
InterProiIPR008967. p53-like_TF_DNA-bd.
IPR001699. TF_T-box.
IPR018186. TF_T-box_CS.
[Graphical view]
PANTHERiPTHR11267. PTHR11267. 1 hit.
PfamiPF00907. T-box. 1 hit.
[Graphical view]
PRINTSiPR00937. TBOX.
SMARTiSM00425. TBOX. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS01283. TBOX_1. 1 hit.
PS01264. TBOX_2. 1 hit.
PS50252. TBOX_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiD9ZGG0_HUMAN
AccessioniPrimary (citable) accession number: D9ZGG0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: July 22, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.