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D9TLQ2 (D9TLQ2_THETC) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. RuleBase RU000544 HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020633

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020633.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding16 – 238ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding89 – 924ATP By similarity HAMAP-Rule MF_00124

Sites

Active site901Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1491Zinc By similarity HAMAP-Rule MF_00124
Metal binding1841Zinc By similarity HAMAP-Rule MF_00124
Metal binding1871Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
D9TLQ2 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: F3B78F8EB48768C3

FASTA19321,642
        10         20         30         40         50         60 
MIYGPKDHGY IEVITGPMFS GKSEELIRRI KRAKIAKQKV QVFKPAIDDR YSIDKVVSHN 

        70         80         90        100        110        120 
GDNMHAIAIV KASEILTYAE EDTDVFAIDE VQFLDYEIVD IVKEIADSGK RVICAGLDMD 

       130        140        150        160        170        180 
FRGEPFGPTP ELMAIAEFVD KLTAICMKCG NPATRTQRLI NGKPANYDDP IIMVGAKESY 

       190 
EARCRKCHEV PRT 

« Hide

References

[1]"Complete sequence of Thermoanaerobacterium thermosaccharolyticum DSM 571."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N., Hemme C.L., Woyke T.
Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002171 Genomic DNA. Translation: ADL69993.1.
RefSeqYP_003853077.1. NC_014410.1.

3D structure databases

ProteinModelPortalD9TLQ2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADL69993; ADL69993; Tthe_2537.
GeneID9708123.
KEGGttm:Tthe_2537.
PATRIC42454506. VBITheThe89703_2575.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000076390.
KOK00857.

Enzyme and pathway databases

BioCycTTHE580327:GHGH-2611-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD9TLQ2_THETC
AccessionPrimary (citable) accession number: D9TLQ2
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: April 16, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)