Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

dTDP-glucose 4,6-dehydratase

Gene

Micau_1179

Organism
Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.UniRule annotation

Cofactori

NAD+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
dTDP-glucose 4,6-dehydrataseUniRule annotation (EC:4.2.1.46UniRule annotation)
Gene namesi
Ordered Locus Names:Micau_1179Imported
OrganismiMicromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442)Imported
Taxonomic identifieri644283 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeMicromonospora
Proteomesi
  • UP000001908 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi644283.Micau_1179.

Structurei

3D structure databases

ProteinModelPortaliD9TDA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 313NAD(P)-bd_domInterPro annotationAdd BLAST310

Sequence similaritiesi

Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1B. Bacteria.
COG1088. LUCA.
HOGENOMiHOG000168006.
KOiK01710.
OMAiMIPTIIR.
OrthoDBiPOG091H044P.

Family and domain databases

InterProiView protein in InterPro
IPR005888. dTDP_Gluc_deHydtase.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
PfamiView protein in Pfam
PF16363. GDP_Man_Dehyd. 1 hit.
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01181. dTDP_gluc_dehyt. 1 hit.
PROSITEiView protein in PROSITE
PS00061. ADH_SHORT. 1 hit.

Sequencei

Sequence statusi: Complete.

D9TDA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILVTGGAG FIGSEYVRML LGVPGGDASG VPVEDPAALT VLDKLTYSGN
60 70 80 90 100
LANLAPVRDD PRLRFVRGDI CDPALVDEVV PGHDVIVHFA AESHVDRSIT
110 120 130 140 150
GAAPFVTTNV LGTQTLLDAA LRHGISRFVH VSTDEVYGSI DSGSWTEDWP
160 170 180 190 200
LAPNSPYSAS KAGSDLLALS YHRTHGLDVV VTRCSNNYGP YQFPEKVVPL
210 220 230 240 250
FVTNLLDGGT VPLYGDGGNV RDWLHVHDHC RGVAMVQEKG RAGEVYHIGG
260 270 280 290 300
GTELTNRQLT ERLLATCGAG WDRVVPVTDR KGHDRRYSLD IGKISSELGY
310 320 330
APSIDLDRGL AETVRWYRDN RAWWEPLKTA GPE
Length:333
Mass (Da):36,152
Last modified:October 5, 2010 - v1
Checksum:i039A398F58F958AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002162 Genomic DNA. Translation: ADL44741.1.
RefSeqiWP_013284380.1. NC_014391.1.

Genome annotation databases

EnsemblBacteriaiADL44741; ADL44741; Micau_1179.
GeneIDi32161818.
KEGGimau:Micau_1179.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD9TDA3_MICAI
AccessioniPrimary (citable) accession number: D9TDA3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: July 5, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported