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Protein

Beta-galactosidase

Gene

Micau_3147

Organism
Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei114 – 1141SubstrateUniRule annotation
Metal bindingi118 – 1181ZincUniRule annotation
Binding sitei152 – 1521SubstrateUniRule annotation
Active sitei153 – 1531Proton donorUniRule annotation
Metal bindingi158 – 1581ZincUniRule annotation
Metal bindingi160 – 1601ZincUniRule annotation
Active sitei312 – 3121NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMAUR644283:GHOD-3179-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Short name:
Beta-galUniRule annotation
Gene namesi
Ordered Locus Names:Micau_3147Imported
OrganismiMicromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)Imported
Taxonomic identifieri644283 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeMicromonospora
ProteomesiUP000001908 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi644283.Micau_3147.

Structurei

3D structure databases

ProteinModelPortaliD9TCH8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 42 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000117811.
KOiK12308.
OMAiLTHGSRD.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.

Sequencei

Sequence statusi: Complete.

D9TCH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTKALWDDG RLCYGGDWNP EQWPPDVWRE DVALMRAAGV NLVTVGVFAW
60 70 80 90 100
SRLEPEPGRY TLDWLDDVLD LLHTGGIRAA LATPTASPPP WFSLRHPDAL
110 120 130 140 150
PLTADGVRLH HGSRDTYCAA APAYRDAARG IAEVLAARYA HHPALALWHV
160 170 180 190 200
HNEYGTTCHC PHAETAFRHW LTTRYGDLDA LNDAWVTSFW SQHYSDWAQV
210 220 230 240 250
GTPRATQYLA NPGQLLDFRR FWSDTLLSAY TEQRDLLRAA NPAVPVTTNY
260 270 280 290 300
VLGDWVPVDH ARWAREVDLV AIDHYPSATD LGAEEQTAFA ADLARGWARH
310 320 330 340 350
GAGRPVPWLL MESAPNQIHT AGRMHTKEPG RMIRHSLAHI ARGSAGVMFF
360 370 380 390 400
QWRAPAGGAE RFHSAVVSHA GPDTRVFREA ADLGAALGRL AGAAPGRVQA
410 420 430 440 450
AVAIAYDAAS GWALRHPGMP RDGLDHPGEA AAVHRALWHA GVTADVVPPG
460 470 480 490 500
APLDGARLLV LPALYLASDA TVDWVRRHVH DGGHLLVTWL SGVADEHARV
510 520 530 540 550
RLGGYPGAYR DLLGVRVEEF HPLADDEHVP LTGGGTGRIW SETVHPAGAE
560 570 580 590 600
TVSAYAGGVP AGRPAITRNR VGDAYAWYVS TRPDDDTYRR LLTEAARLAG
610 620 630 640 650
VAPACPGAPE GVEAVRRHDG LLYLLNHTDR PQRVPAAGFE LLTGAAVDGE
660
LTVAPGAVAV VREKTP
Length:666
Mass (Da):72,216
Last modified:October 5, 2010 - v1
Checksum:iD6C588739D9D1214
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002162 Genomic DNA. Translation: ADL46676.1.
RefSeqiWP_013286302.1. NC_014391.1.
YP_003836252.1. NC_014391.1.

Genome annotation databases

EnsemblBacteriaiADL46676; ADL46676; Micau_3147.
KEGGimau:Micau_3147.
PATRICi42392003. VBIMicAur74833_3153.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002162 Genomic DNA. Translation: ADL46676.1.
RefSeqiWP_013286302.1. NC_014391.1.
YP_003836252.1. NC_014391.1.

3D structure databases

ProteinModelPortaliD9TCH8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi644283.Micau_3147.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADL46676; ADL46676; Micau_3147.
KEGGimau:Micau_3147.
PATRICi42392003. VBIMicAur74833_3153.

Phylogenomic databases

HOGENOMiHOG000117811.
KOiK12308.
OMAiLTHGSRD.

Enzyme and pathway databases

BioCyciMAUR644283:GHOD-3179-MONOMER.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Micromonospora aurantiaca ATCC 27029."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G., Hirsch A.M., Woyke T.
    Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442Imported.

Entry informationi

Entry nameiD9TCH8_MICAI
AccessioniPrimary (citable) accession number: D9TCH8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: June 24, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.