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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371UniRule annotation
Active sitei574 – 5741UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMAUR644283:GHOD-892-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Micau_0880Imported
OrganismiMicromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)Imported
Taxonomic identifieri644283 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeMicromonospora
ProteomesiUP000001908 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi644283.Micau_0880.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D9TAY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDQHDHDGP DAALRADIRR LGTLLGQTLA RQEGRPLLDL VEEIRAQVRS
60 70 80 90 100
DVPAAAQRLA GLDVTTGTKL ARAFSTYFHL ANITEQVHRA RDLRRRRATH
110 120 130 140 150
GGWLDQAAKM IAERGVPAEE IAAAARRLAV RPVFTAHPTE AARRSILSKL
160 170 180 190 200
RAVADELDTE TANAILYGAS DEGPANRRLA ELLDLMWQTD ELRLDRPDPT
210 220 230 240 250
DEARNAIYYL RDLYAEAAPQ VLDDLADTLR TLGVETSPTS RPLSFGTWIG
260 270 280 290 300
GDRDGNPFVT PVVTREVLRI QHEHGIAATE KAMDELITEV SVSRRLRAVS
310 320 330 340 350
LDLSASLAKD LDALPEVAPR FRRVNAEEPY RLKARCVKAK LANTRERLRA
360 370 380 390 400
DTPHVPGRDY RGSSELIADL ELLRASLARN SGQLTAVGRL ASAIRTVSAF
410 420 430 440 450
GLHLATMDIR EHAEKHHEVL AQLYEAVGEV SDYPALSRLE RTKLLADELT
460 470 480 490 500
GRRPLSTQDS PLTESARKTF DVFAAIREAQ DRFGPEVIES YIISMTLGVD
510 520 530 540 550
DVLAAVVLAR EAGLVDVHSG RARIGIVPLL ETPAELNAGG ELLDELLSLP
560 570 580 590 600
AYRALVAARG DVQEVMLGYS DSNKEAGITT SQWSIHRAQR SLRDVAARHG
610 620 630 640 650
VHLRLFHGRG GTVGRGGGPT HDAILAQPYG TLDGAIKVTE QGEVISDKYT
660 670 680 690 700
LPALARENLE LTVAAVLQAT LLHTAPRQPA EMLERWDAAM DVVSESAFRS
710 720 730 740 750
YRSLVEDPDL PAYFWASTPT ELLGALNIGS RPAKRPNTGA GLSGLRAIPW
760 770 780 790 800
VFGWTQTRQI VPGWFGVGSG LAAARAAGLA DVLAEMNRNW HFFRTFLSNV
810 820 830 840 850
EMMLTKTDLT IARRYVETLV PKKLHPIFDK IEQEYELTKQ EVLAVTAAPA
860 870 880 890 900
LLDNSPVLQR TLAVRDTYLE PLHHLQVALL RQYRESGAAG RAVVTAPGGR
910 920
RAPNDGTALE RALLTTVNGI AAGMRNTG
Length:928
Mass (Da):101,608
Last modified:October 5, 2010 - v1
Checksum:i8E337054202D4B25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002162 Genomic DNA. Translation: ADL44444.1.
RefSeqiWP_013284083.1. NC_014391.1.
YP_003834020.1. NC_014391.1.

Genome annotation databases

EnsemblBacteriaiADL44444; ADL44444; Micau_0880.
KEGGimau:Micau_0880.
PATRICi42387448. VBIMicAur74833_0895.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002162 Genomic DNA. Translation: ADL44444.1.
RefSeqiWP_013284083.1. NC_014391.1.
YP_003834020.1. NC_014391.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi644283.Micau_0880.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADL44444; ADL44444; Micau_0880.
KEGGimau:Micau_0880.
PATRICi42387448. VBIMicAur74833_0895.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciMAUR644283:GHOD-892-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Micromonospora aurantiaca ATCC 27029."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G., Hirsch A.M., Woyke T.
    Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442Imported.

Entry informationi

Entry nameiD9TAY9_MICAI
AccessioniPrimary (citable) accession number: D9TAY9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: June 24, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.