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Protein

Ornithine carbamoyltransferase, catabolic

Gene

arcB

Organism
Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei28 – 281Important for structural integrityUniRule annotation
Binding sitei104 – 1041Carbamoyl phosphateUniRule annotation
Binding sitei131 – 1311Carbamoyl phosphateUniRule annotation
Sitei144 – 1441Important for structural integrityUniRule annotation

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. ornithine carbamoyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine catabolic process to ornithine Source: UniProtKB-UniPathway
  2. arginine deiminase pathway Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotation

Keywords - Biological processi

Arginine metabolismUniRule annotation

Enzyme and pathway databases

BioCyciCCEL573061:GIXD-2211-MONOMER.
UniPathwayiUPA00254; UER00365.

Names & Taxonomyi

Protein namesi
Recommended name:
Ornithine carbamoyltransferase, catabolicUniRule annotation (EC:2.1.3.3UniRule annotation)
Short name:
OTCaseUniRule annotation
Gene namesi
Name:arcBUniRule annotation
Ordered Locus Names:Clocel_2146Imported
OrganismiClostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B)Imported
Taxonomic identifieri573061 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000002730 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD9SN23.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni53 – 575Carbamoyl phosphate bindingUniRule annotation
Regioni265 – 2684Ornithine bindingUniRule annotation

Sequence similaritiesi

Belongs to the ATCase/OTCase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000022686.
KOiK00611.
OMAiHNMANTL.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_01109. OTCase.
InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. OTCase_ArgI.
[Graphical view]
PfamiPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSiPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.
PROSITEiPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D9SN23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAKDLLTLK DLSKEEILEI IDLSEQLKYE TKHGIEHHYL KGKTLGMIFR
60 70 80 90 100
KHSTRTRVSF EVGMYQLGGF ALFLNSSDIQ MSRGEAIEDT GRVLARYLDG
110 120 130 140 150
IMIRTFDQRE VEELAAASRI PIINGLTDEE HPCQVLADLL TIKENKRKFK
160 170 180 190 200
GLKVAFVGDG HNMANTLMIG CLKVDMDFSI ATPKGYETKE KIIEAARLVE
210 220 230 240 250
KDSLGTLTIT NSPEEAVKDA DVVITDVWTS MGQETEKNLR KEIFKSYQVN
260 270 280 290 300
KQLMSFAKID AMVLHCLPAH KDEEITTEIF EEHQEEIFEE SENRLHVQKA
310
VLVKLMGKNN
Length:310
Mass (Da):35,263
Last modified:October 5, 2010 - v1
Checksum:i6ABA3A4D0129860C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002160 Genomic DNA. Translation: ADL51889.1.
RefSeqiYP_003843653.1. NC_014393.1.

Genome annotation databases

EnsemblBacteriaiADL51889; ADL51889; Clocel_2146.
KEGGiccb:Clocel_2146.
PATRICi41739986. VBICloCel81632203721_3698.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002160 Genomic DNA. Translation: ADL51889.1.
RefSeqiYP_003843653.1. NC_014393.1.

3D structure databases

ProteinModelPortaliD9SN23.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADL51889; ADL51889; Clocel_2146.
KEGGiccb:Clocel_2146.
PATRICi41739986. VBICloCel81632203721_3698.

Phylogenomic databases

HOGENOMiHOG000022686.
KOiK00611.
OMAiHNMANTL.

Enzyme and pathway databases

UniPathwayiUPA00254; UER00365.
BioCyciCCEL573061:GIXD-2211-MONOMER.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_01109. OTCase.
InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. OTCase_ArgI.
[Graphical view]
PfamiPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSiPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.
PROSITEiPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35296 / DSM 3052 / OCM 3 / 743BImported.

Entry informationi

Entry nameiD9SN23_CLOC7
AccessioniPrimary (citable) accession number: D9SN23
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: April 29, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.