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Protein
Submitted name:

Ornithine carbamoyltransferase

Gene

Clocel_2146

Organism
Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei80Carbamoyl phosphateUniRule annotation1
Binding sitei104Carbamoyl phosphateUniRule annotation1
Binding sitei162OrnithineUniRule annotation1
Binding sitei226OrnithineUniRule annotation1
Binding sitei294Carbamoyl phosphateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Ornithine carbamoyltransferaseImported (EC:2.1.3.3Imported)
Gene namesi
Ordered Locus Names:Clocel_2146Imported
OrganismiClostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B)Imported
Taxonomic identifieri573061 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000002730 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi573061.Clocel_2146.

Structurei

3D structure databases

ProteinModelPortaliD9SN23.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 144OTCace_NInterPro annotationAdd BLAST141
Domaini150 – 304OTCaceInterPro annotationAdd BLAST155

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni53 – 56Carbamoyl phosphate bindingUniRule annotation4
Regioni131 – 134Carbamoyl phosphate bindingUniRule annotation4
Regioni230 – 231Ornithine bindingUniRule annotation2
Regioni266 – 267Carbamoyl phosphate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the ATCase/OTCase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DBV. Bacteria.
COG0078. LUCA.
HOGENOMiHOG000022686.
KOiK00611.
OMAiVECVITD.
OrthoDBiPOG091H0543.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_01109. OTCase. 1 hit.
InterProiView protein in InterPro
IPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. OTCase_ArgI.
PfamiView protein in Pfam
PF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
PRINTSiPR00100. AOTCASE.
PR00102. OTCASE.
TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.
PROSITEiView protein in PROSITE
PS00097. CARBAMOYLTRANSFERASE. 1 hit.

Sequencei

Sequence statusi: Complete.

D9SN23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAKDLLTLK DLSKEEILEI IDLSEQLKYE TKHGIEHHYL KGKTLGMIFR
60 70 80 90 100
KHSTRTRVSF EVGMYQLGGF ALFLNSSDIQ MSRGEAIEDT GRVLARYLDG
110 120 130 140 150
IMIRTFDQRE VEELAAASRI PIINGLTDEE HPCQVLADLL TIKENKRKFK
160 170 180 190 200
GLKVAFVGDG HNMANTLMIG CLKVDMDFSI ATPKGYETKE KIIEAARLVE
210 220 230 240 250
KDSLGTLTIT NSPEEAVKDA DVVITDVWTS MGQETEKNLR KEIFKSYQVN
260 270 280 290 300
KQLMSFAKID AMVLHCLPAH KDEEITTEIF EEHQEEIFEE SENRLHVQKA
310
VLVKLMGKNN
Length:310
Mass (Da):35,263
Last modified:October 5, 2010 - v1
Checksum:i6ABA3A4D0129860C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002160 Genomic DNA. Translation: ADL51889.1.
RefSeqiWP_010076892.1. NC_014393.1.

Genome annotation databases

EnsemblBacteriaiADL51889; ADL51889; Clocel_2146.
KEGGiccb:Clocel_2146.
PATRICi41739986. VBICloCel81632203721_3698.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002160 Genomic DNA. Translation: ADL51889.1.
RefSeqiWP_010076892.1. NC_014393.1.

3D structure databases

ProteinModelPortaliD9SN23.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi573061.Clocel_2146.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADL51889; ADL51889; Clocel_2146.
KEGGiccb:Clocel_2146.
PATRICi41739986. VBICloCel81632203721_3698.

Phylogenomic databases

eggNOGiENOG4105DBV. Bacteria.
COG0078. LUCA.
HOGENOMiHOG000022686.
KOiK00611.
OMAiVECVITD.
OrthoDBiPOG091H0543.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_01109. OTCase. 1 hit.
InterProiView protein in InterPro
IPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. OTCase_ArgI.
PfamiView protein in Pfam
PF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
PRINTSiPR00100. AOTCASE.
PR00102. OTCASE.
TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.
PROSITEiView protein in PROSITE
PS00097. CARBAMOYLTRANSFERASE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD9SN23_CLOC7
AccessioniPrimary (citable) accession number: D9SN23
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 10, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.