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Protein

Alanine racemase

Gene

Galf_0614

Organism
Gallionella capsiferriformans (strain ES-2) (Gallionella ferruginea capsiferriformans (strain ES-2))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (Galf_0614)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei34Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei129SubstrateUniRule annotation1
Active sitei251Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei299Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciGCAP395494:G1GMJ-624-MONOMER
UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Galf_0614Imported
OrganismiGallionella capsiferriformans (strain ES-2) (Gallionella ferruginea capsiferriformans (strain ES-2))Imported
Taxonomic identifieri395494 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesGallionellaceaeGallionella
Proteomesi
  • UP000001235 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei34N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi395494.Galf_0614

Structurei

3D structure databases

ProteinModelPortaliD9SCW7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini230 – 353Ala_racemase_CInterPro annotationAdd BLAST124

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CJ4 Bacteria
COG0787 LUCA
HOGENOMiHOG000031446
KOiK01775
OMAiWRGPILL
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.102 hits
3.20.20.101 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

D9SCW7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRPIQALID QNALENNLHV ARRAASSRIM AVIKADGYGH GLLRVAEALA
60 70 80 90 100
AAEGFALLDI QDAVRLREAG YRQTILLLEG FFDAADLALI AAYELTTVIH
110 120 130 140 150
SNWQIALLDA YPGRGTLDVW LKVNSGMHRL GFSPEGVNAA MKSLRAHAAV
160 170 180 190 200
REITLMSHFS HADEPRGVSL QLALINEIAS EYRVARSLAN SAALLRYPAT
210 220 230 240 250
HGDWVRPGVM LYGASPFADT SAQQLGLKPV MTLSSRIIAI QNLQAGDEVG
260 270 280 290 300
YAGVFRADRT MRIGVVACGY ADGYPRHAPN GTPVLVDGRK TQLLGRISMD
310 320 330 340 350
MLCVDLTALP DSGMGAQVTL WGQGLPVETV AAAAGTISYE LMCGLTARVP

VRL
Length:353
Mass (Da):37,881
Last modified:October 5, 2010 - v1
Checksum:i6F8D68A0B6655292
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002159 Genomic DNA Translation: ADL54656.1
RefSeqiWP_013292598.1, NC_014394.1

Genome annotation databases

EnsemblBacteriaiADL54656; ADL54656; Galf_0614
KEGGigca:Galf_0614

Similar proteinsi

Entry informationi

Entry nameiD9SCW7_GALCS
AccessioniPrimary (citable) accession number: D9SCW7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: February 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported