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D9RAA6 (D9RAA6_CLOSW) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site381Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2661Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1351Substrate By similarity HAMAP-Rule MF_01201
Binding site3141Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue381N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D9RAA6 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 862F1266793611E6

FASTA39543,450
        10         20         30         40         50         60 
MKLYSRVYET VDLDAIRHNM EAMKANLKDG TRMIGVVKSD GYGHGAVPVA WAIDPYVWGY 

        70         80         90        100        110        120 
AVATVEEGVI LRKHGIRKPI LVLGVVPYEG YGLLVEHGIS SAVFQLKRAE RLSSLAVREG 

       130        140        150        160        170        180 
KKAVIHLVLD TGMSRIGYPV TEEAAKEAAT ICGLPGIEVE GLFTHFAKAD ERDKKATDHQ 

       190        200        210        220        230        240 
LEQYQKFVAM LADRGITIPM LHCSNSAGIL DLQRANLHAV RAGISIYGIY PSGEVDRDTV 

       250        260        270        280        290        300 
KLRPAMELKS FISYVKKIGP GTSVSYGGTF TADREMTVAT VPVGYGDGYP RNLSGKGEVL 

       310        320        330        340        350        360 
IRGQRARILG RVCMDQFMVD VTGIHEAEEE DEVVLIGRQG KEEITVEDLA MAGGGFHYEI 

       370        380        390 
VCDIGKRVPR IYLEDGRVIG TKDYFNDCYK GFCRV 

« Hide

References

[1]"Complete sequence of Clostridium saccharolyticum WM1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N. expand/collapse author list , Mouttaki H., Lin L., Zhou J., Hemme C.L., Woyke T.
Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35040 / DSM 2544 / NRCC 2533 / WM1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002109 Genomic DNA. Translation: ADL04184.1.
RefSeqYP_003821807.1. NC_014376.1.

3D structure databases

ProteinModelPortalD9RAA6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADL04184; ADL04184; Closa_1587.
GeneID9506877.
KEGGcsh:Closa_1587.
PATRIC42264680. VBICloSac91065_1719.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
OMALWQLEAI.

Enzyme and pathway databases

BioCycCSAC610130:GHTP-1640-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD9RAA6_CLOSW
AccessionPrimary (citable) accession number: D9RAA6
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: July 9, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)