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D9RAA6

- D9RAA6_CLOSW

UniProt

D9RAA6 - D9RAA6_CLOSW

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Protein

Alanine racemase

Gene
Closa_1587
Organism
Clostridium saccharolyticum (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei38 – 381Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei135 – 1351Substrate By similarityUniRule annotation
Active sitei266 – 2661Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei314 – 3141Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciCSAC610130:GHTP-1640-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Closa_1587Imported
OrganismiClostridium saccharolyticum (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1)Imported
Taxonomic identifieri610130 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
ProteomesiUP000001662: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei38 – 381N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD9RAA6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiLWQLEAI.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D9RAA6-1 [UniParc]FASTAAdd to Basket

« Hide

MKLYSRVYET VDLDAIRHNM EAMKANLKDG TRMIGVVKSD GYGHGAVPVA    50
WAIDPYVWGY AVATVEEGVI LRKHGIRKPI LVLGVVPYEG YGLLVEHGIS 100
SAVFQLKRAE RLSSLAVREG KKAVIHLVLD TGMSRIGYPV TEEAAKEAAT 150
ICGLPGIEVE GLFTHFAKAD ERDKKATDHQ LEQYQKFVAM LADRGITIPM 200
LHCSNSAGIL DLQRANLHAV RAGISIYGIY PSGEVDRDTV KLRPAMELKS 250
FISYVKKIGP GTSVSYGGTF TADREMTVAT VPVGYGDGYP RNLSGKGEVL 300
IRGQRARILG RVCMDQFMVD VTGIHEAEEE DEVVLIGRQG KEEITVEDLA 350
MAGGGFHYEI VCDIGKRVPR IYLEDGRVIG TKDYFNDCYK GFCRV 395
Length:395
Mass (Da):43,450
Last modified:October 5, 2010 - v1
Checksum:i862F1266793611E6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002109 Genomic DNA. Translation: ADL04184.1.
RefSeqiYP_003821807.1. NC_014376.1.

Genome annotation databases

EnsemblBacteriaiADL04184; ADL04184; Closa_1587.
GeneIDi9506877.
KEGGicsh:Closa_1587.
PATRICi42264680. VBICloSac91065_1719.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002109 Genomic DNA. Translation: ADL04184.1 .
RefSeqi YP_003821807.1. NC_014376.1.

3D structure databases

ProteinModelPortali D9RAA6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADL04184 ; ADL04184 ; Closa_1587 .
GeneIDi 9506877.
KEGGi csh:Closa_1587.
PATRICi 42264680. VBICloSac91065_1719.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.
OMAi LWQLEAI.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci CSAC610130:GHTP-1640-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35040 / DSM 2544 / NRCC 2533 / WM1.

Entry informationi

Entry nameiD9RAA6_CLOSW
AccessioniPrimary (citable) accession number: D9RAA6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: September 3, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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