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Protein

Elongation factor Tu

Gene

tuf

Organism
Acetohalobium arabaticum (strain ATCC 49924 / DSM 5501 / Z-7288)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi80 – 84GTPUniRule annotation5
Nucleotide bindingi135 – 138GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAARA574087:G1GMC-174-MONOMER
AARA574087:G1GMC-187-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Acear_0147Imported, Acear_0160Imported
OrganismiAcetohalobium arabaticum (strain ATCC 49924 / DSM 5501 / Z-7288)Imported
Taxonomic identifieri574087 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaHalanaerobialesHalobacteroidaceaeAcetohalobium
Proteomesi
  • UP000001661 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi574087.Acear_0160

Structurei

3D structure databases

ProteinModelPortaliD9QTD4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 208Tr-type GInterPro annotationAdd BLAST199

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili139 – 159Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OMAiAIRDMGM
OrthoDBiPOG091H00LA

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

D9QTD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEKFERDK PHMNIGTIGH VDHGKTTTTA AITKVLSKGE EGSANFEDID
60 70 80 90 100
NAPEEQERGI TIATSHVEYE TENRHYAHVD CPGHADYVKN MITGAAQMDG
110 120 130 140 150
ALLVVSAADG PMPQTREHLL LARQVNVPNI VVFLNKADMV DDEELIELVE
160 170 180 190 200
MEVRELLNEY DFNGDEVPII VGSGLKALEC GCGDRDCEWC GQILELMDAI
210 220 230 240 250
DEYLPEPERD TDKPFLLPVE DVFTIKGRGT VATGRLERGK LHPGDEAELV
260 270 280 290 300
GVKDTQETVV TGVEMFRKML DEAVAGDNIG ALLRGVDREE IERGQVLAEP
310 320 330 340 350
GSITPHTEFE AEVYVLSKDE GGRHTPFFDG YRPQFYFRTT DVTGDINLPD
360 370 380 390
DVEMVMPGDN VEMGVKLITP IAMEEGLRFA IREGGKTVGA GVITEIIE
Length:398
Mass (Da):43,870
Last modified:October 5, 2010 - v1
Checksum:i95FB7611DDA2597A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002105 Genomic DNA Translation: ADL11698.1
CP002105 Genomic DNA Translation: ADL11711.1
RefSeqiWP_013277145.1, NC_014378.1

Genome annotation databases

EnsemblBacteriaiADL11698; ADL11698; Acear_0147
ADL11711; ADL11711; Acear_0160
KEGGiaar:Acear_0147
aar:Acear_0160

Similar proteinsi

Entry informationi

Entry nameiD9QTD4_ACEAZ
AccessioniPrimary (citable) accession number: D9QTD4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 23, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health