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D9QM71 (D9QM71_BRESC) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047
EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Bresu_2690
OrganismBrevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81) (Caulobacter subvibrioides) [Complete proteome] [HAMAP]
Taxonomic identifier633149 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Brevundimonas ›

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS000291

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS000291

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS000291

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS000291

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS000291.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047 SAAS SAAS000291

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain106 – 305200ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding133 – 18654ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2581Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2721Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2721Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2741Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D9QM71 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: B894F6D7174551E2

FASTA31132,992
        10         20         30         40         50         60 
MSRSLSELHV AVLLGGLSSE RDVSLSSGKG CADALEAQGA RVTRVDAGRD LAQVLAELKP 

        70         80         90        100        110        120 
DVVLNALHGE WGEDGCVQGI LETLQIPYTH SGVLASALTM DKDKTKAVLN AAGVKVPGGG 

       130        140        150        160        170        180 
LFDRHAVSAG HVIPPPYVIK PNAEGSSVGV YLVREGDAPQ PEPGSDSWTY GDLVMVEPYI 

       190        200        210        220        230        240 
PGKELAVAVI GEATGPRALT VTDITPVKGF YDYEAKYAPG GSVHKLPADL PPHVFEAAMR 

       250        260        270        280        290        300 
ESEQAHAALG CRGVSRSDFR YDDVKDELVL LEVNTQPGMT PTSLVPEQAA YCGMSYQDLV 

       310 
RWMVEDASCP R

« Hide

References

[1]"Genome sequences of eight morphologically diverse alphaproteobacteria."
US DOE Joint Genome Institute
Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.
J. Bacteriol. 193:4567-4568(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002102 Genomic DNA. Translation: ADL01997.1.
RefSeqYP_003819620.1. NC_014375.1.

3D structure databases

ProteinModelPortalD9QM71.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADL01997; ADL01997; Bresu_2690.
GeneID9504573.
KEGGbsb:Bresu_2690.
PATRIC42204623. VBIBreSub37974_2716.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011592.
KOK01921.
OMAVEDASCD.

Enzyme and pathway databases

BioCycBSUB633149:GHJJ-2731-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD9QM71_BRESC
AccessionPrimary (citable) accession number: D9QM71
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 29, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info