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Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 subunit

Gene

Bresu_0468

Organism
Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81) (Caulobacter subvibrioides)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciBSUB633149:GHJJ-471-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, E1 subunitImported (EC:1.2.4.2Imported)
Gene namesi
Ordered Locus Names:Bresu_0468Imported
OrganismiBrevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81) (Caulobacter subvibrioides)Imported
Taxonomic identifieri633149 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeBrevundimonas
ProteomesiUP000002696: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD9QKF7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000259586.
KOiK00164.
OMAiQNQGAWF.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

D9QKF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADDAGRLNQ VFAETSFLYG SNAAFIEELH DKWAADPSSV SAEWRGFFDQ
60 70 80 90 100
LRDSAATVQA SSAAGSWGRS QATEPTEETG VFDGRWPAPK ADPKAKPAAG
110 120 130 140 150
APAAPAATGA SAEEVRAAAH DSIRVLMLIR SYRVRGHLQA TLDPLGIEAR
160 170 180 190 200
TNNPELTPEF YGFTEADMDR PIYLDGVLGL QTGTIREVLA ILNRTYCGNI
210 220 230 240 250
GIQFMHIAEP EEKSWLQQRF EGADAFEKNG FTREGKIAIL NKLIEAEGFE
260 270 280 290 300
RFLHKRFPGT KRFGLDGGEA MVPALEQMIK RGGALGVDEI VIGMAHRGRL
310 320 330 340 350
NTLAAVMGKP YRAIFHEFQG GSTVPSDIEG SGDVKYHMGA SSNREFDGNH
360 370 380 390 400
VHLSLTANPS HLEIVNPVVL GKARAKQAFD IREANAGLPE AQWALDRSKV
410 420 430 440 450
MPLLIHGDAA FAGQGVVAEC FALMGLKGYR TGGTMHFVIN NQIGFTTSPR
460 470 480 490 500
NSRSSPYPSD VALMVQAPIF HVNGDDPEAV VFAAKVATEF RQKFKKDVVV
510 520 530 540 550
DMFCYRRFGH NEGDDPTFTQ PVMYSKIRSL PSTREIYSRR LVEEGVLSAA
560 570 580 590 600
EVDAEIARFE AYLDEQFEAG KSFVADKADW LDGQWKGVGL PDGEERRGDT
610 620 630 640 650
AVAEAKLKDL GHRLTTIPNQ VDIHKTLKRV IDARRATIDK GTDIDWATAE
660 670 680 690 700
SLAFASLLTE GFPVRLSGQD SVRGTFSQRH SGIVDQTTEE RYVPLNNLGG
710 720 730 740 750
DHQHFEVIDS ALSEEAVLGF EYGYALSDPN TLVMWEAQFG DFVNGAQVVI
760 770 780 790 800
DQFISSGERK WLRMCGLTML LPHGYEGQGP EHSSARLERF LQQCAEDNMQ
810 820 830 840 850
VANCTTPANY FHILRRQMHR PFRKPLIIMT PKSLLRHKKA VSTLKDMAEG
860 870 880 890 900
SSFHRVLHDD AQTRPEVSGI TIKGDKDIRR VVLCSGKVYY DLLDAREKKG
910 920 930 940 950
VNDVYLMRLE QFYPWPIKSL STELARFPNA ELVWCQEEPK NMGGWTFVDP
960 970 980 990
WLELTLEKLD VKSKRARYVG RPASASTAAG LMSRHLKELE AFTSEALA
Length:998
Mass (Da):110,567
Last modified:October 5, 2010 - v1
Checksum:i66FA8C956EFE4E95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002102 Genomic DNA. Translation: ADK99782.1.
RefSeqiWP_013267886.1. NC_014375.1.
YP_003817406.1. NC_014375.1.

Genome annotation databases

EnsemblBacteriaiADK99782; ADK99782; Bresu_0468.
GeneIDi9502314.
KEGGibsb:Bresu_0468.
PATRICi42200064. VBIBreSub37974_0472.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002102 Genomic DNA. Translation: ADK99782.1.
RefSeqiWP_013267886.1. NC_014375.1.
YP_003817406.1. NC_014375.1.

3D structure databases

ProteinModelPortaliD9QKF7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADK99782; ADK99782; Bresu_0468.
GeneIDi9502314.
KEGGibsb:Bresu_0468.
PATRICi42200064. VBIBreSub37974_0472.

Phylogenomic databases

HOGENOMiHOG000259586.
KOiK00164.
OMAiQNQGAWF.

Enzyme and pathway databases

BioCyciBSUB633149:GHJJ-471-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81Imported.

Entry informationi

Entry nameiD9QKF7_BRESC
AccessioniPrimary (citable) accession number: D9QKF7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: February 4, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.