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D9QHF4

- D9QHF4_BRESC

UniProt

D9QHF4 - D9QHF4_BRESC

Protein

Alanine racemase

Gene

Bresu_1809

Organism
Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81) (Caulobacter subvibrioides)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (05 Oct 2010)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei128 – 1281SubstrateUniRule annotation
    Active sitei242 – 2421Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei290 – 2901Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBSUB633149:GHJJ-1832-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Bresu_1809Imported
    OrganismiBrevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81) (Caulobacter subvibrioides)Imported
    Taxonomic identifieri633149 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeBrevundimonas
    ProteomesiUP000002696: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD9QHF4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031445.
    KOiK01775.
    OMAiRIGISIY.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D9QHF4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTATATLTVD LDALAHNVHA LAAISGAPVH PVVKADSYGL GAIPVAQRLL    50
    REGSRTFFVA RLAEGIALRS ALGPEPTLYV LDGCVGDAAP ALKAADLRPI 100
    LNHGDQLMAW RAADGGACGL QIDTGMNRLG FRIEDAPAPF EGLSLVMSHL 150
    ACADEPAQPM NRRQRDAFAA AAARYPGALR SFANSGGCFL GPDYAFDAVR 200
    PGICLYGGGP EGRPHDRIKP VATLSARVLQ VRDVPAGESI GYSRGFVAPE 250
    ARRIATCGAG YADGVLRSQC PNGQVWVAGS LRPILGRVSM DVIAVDVTGL 300
    DVAVGDPVEL FGPNHLLDDA AAAAGTISYE LLTSVTARVP RRYEG 345
    Length:345
    Mass (Da):35,972
    Last modified:October 5, 2010 - v1
    Checksum:i634141D4653A0C87
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002102 Genomic DNA. Translation: ADL01120.1.
    RefSeqiYP_003818743.1. NC_014375.1.

    Genome annotation databases

    EnsemblBacteriaiADL01120; ADL01120; Bresu_1809.
    GeneIDi9503675.
    KEGGibsb:Bresu_1809.
    PATRICi42202807. VBIBreSub37974_1825.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002102 Genomic DNA. Translation: ADL01120.1 .
    RefSeqi YP_003818743.1. NC_014375.1.

    3D structure databases

    ProteinModelPortali D9QHF4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADL01120 ; ADL01120 ; Bresu_1809 .
    GeneIDi 9503675.
    KEGGi bsb:Bresu_1809.
    PATRICi 42202807. VBIBreSub37974_1825.

    Phylogenomic databases

    HOGENOMi HOG000031445.
    KOi K01775.
    OMAi RIGISIY.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci BSUB633149:GHJJ-1832-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81Imported.

    Entry informationi

    Entry nameiD9QHF4_BRESC
    AccessioniPrimary (citable) accession number: D9QHF4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 5, 2010
    Last sequence update: October 5, 2010
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3