Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

D9Q6L7

- D9Q6L7_CORP1

UniProt

D9Q6L7 - D9Q6L7_CORP1

Protein

Alanine racemase

Gene

alr

Organism
Corynebacterium pseudotuberculosis (strain 1002)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (05 Oct 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei36 – 361Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei135 – 1351SubstrateUniRule annotation
    Active sitei262 – 2621Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei310 – 3101Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCPSE679896:GLBP-433-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:Cp1002_0412Imported
    OrganismiCorynebacterium pseudotuberculosis (strain 1002)Imported
    Taxonomic identifieri679896 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000008684: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei36 – 361N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD9Q6L7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D9Q6L7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNLLEARIDL AAIAHNTRLI KDKAAAQGAQ LMCVVKADGY NHGAVEVATV    50
    MEENGADQFG VATIGEALAL REGGIESSIL SWIWSPEQDL GAAITAEIDL 100
    AAISLEHVKA LVRASESYGK KPVRVTVKVD TGLHRSGVDK QDWRESFCML 150
    RDAENIQVTG VFSHFSSADE SDSTETEQQE RAFLNAIELG RSLGLELPVN 200
    HIANSPATLN RPDLYFDMVR PGLALYGHEP IPGESHGLRE AMSWVGRVTV 250
    VKPIARGEGT SYGLTWRAEQ DGYLCVVPVG YADGLPRSAQ GHLEITIGGR 300
    RYPQVGRVCM DQIVVALGEN PYGVAQGDEA VILGPTGMTA TELATAMGTI 350
    NYELVCRPCG RTVRVFEHSD 370
    Length:370
    Mass (Da):39,926
    Last modified:October 5, 2010 - v1
    Checksum:i0C2920E487111667
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001809 Genomic DNA. Translation: ADL20312.1.
    RefSeqiYP_005680683.1. NC_017300.1.

    Genome annotation databases

    EnsemblBacteriaiADL20312; ADL20312; Cp1002_0412.
    GeneIDi12300724.
    KEGGicpk:Cp1002_0412.
    PATRICi42894532. VBICorPse156913_0427.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001809 Genomic DNA. Translation: ADL20312.1 .
    RefSeqi YP_005680683.1. NC_017300.1.

    3D structure databases

    ProteinModelPortali D9Q6L7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADL20312 ; ADL20312 ; Cp1002_0412 .
    GeneIDi 12300724.
    KEGGi cpk:Cp1002_0412.
    PATRICi 42894532. VBICorPse156913_0427.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci CPSE679896:GLBP-433-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1002Imported.
    2. "Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains."
      Ruiz J.C., D'Afonseca V., Silva A., Ali A., Pinto A.C., Santos A.R., Rocha A.A., Lopes D.O., Dorella F.A., Pacheco L.G., Costa M.P., Turk M.Z., Seyffert N., Moraes P.M., Soares S.C., Almeida S.S., Castro T.L., Abreu V.A.
      , Trost E., Baumbach J., Tauch A., Schneider M.P., McCulloch J., Cerdeira L.T., Ramos R.T., Zerlotini A., Dominitini A., Resende D.M., Coser E.M., Oliveira L.M., Pedrosa A.L., Vieira C.U., Guimaraes C.T., Bartholomeu D.C., Oliveira D.M., Santos F.R., Rabelo E.M., Lobo F.P., Franco G.R., Costa A.F., Castro I.M., Dias S.R., Ferro J.A., Ortega J.M., Paiva L.V., Goulart L.R., Almeida J.F., Ferro M.I., Carneiro N.P., Falcao P.R., Grynberg P., Teixeira S.M., Brommonschenkel S., Oliveira S.C., Meyer R., Moore R.J., Miyoshi A., Oliveira G.C., Azevedo V.
      PLoS ONE 6:E18551-E18551(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1002Imported.

    Entry informationi

    Entry nameiD9Q6L7_CORP1
    AccessioniPrimary (citable) accession number: D9Q6L7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 5, 2010
    Last sequence update: October 5, 2010
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3