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D9Q2U7 (D9Q2U7_ACIS3) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Triosephosphate isomerase HAMAP-Rule MF_00147
Short name=TIM HAMAP-Rule MF_00147
EC=5.3.1.1 HAMAP-Rule MF_00147
Alternative name(s):
Triose-phosphate isomerase HAMAP-Rule MF_00147
Gene names
Name:tpiA HAMAP-Rule MF_00147
Ordered Locus Names:ASAC_1230 EMBL ADL19635.1
OrganismAcidilobus saccharovorans (strain DSM 16705 / VKM B-2471 / 345-15) [Complete proteome] [HAMAP] EMBL ADL19635.1
Taxonomic identifier666510 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Acidilobales › Acidilobaceae › Acidilobus ›

Protein attributes

Sequence length225 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glyceraldehyde 3-phosphate = glycerone phosphate. HAMAP-Rule MF_00147

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP-Rule MF_00147

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. HAMAP-Rule MF_00147

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00147

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00147.

Sequence similarities

Belongs to the triosephosphate isomerase family. HAMAP-Rule MF_00147

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site931Electrophile By similarity HAMAP-Rule MF_00147
Active site1411Proton acceptor By similarity HAMAP-Rule MF_00147
Binding site91Substrate By similarity HAMAP-Rule MF_00147
Binding site111Substrate By similarity HAMAP-Rule MF_00147

Sequences

Sequence LengthMass (Da)Tools
D9Q2U7 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 7B826A75E692D6F8

FASTA22523,851
        10         20         30         40         50         60 
MPRLVFAVNF KAYETAFNEK SLEIAREASK ASSRYGNVRV ILIVPAAIAS KVLQIYDDVY 

        70         80         90        100        110        120 
IEHADPVDYG AYTGYLPAKA ARLLGVRGIL VNHSEHKMIY RDVAKVVETA SKDGIETMAC 

       130        140        150        160        170        180 
ADTPGEAAGL AYLRPTYIAI EPPELIGTGV SVSKARPEVI TEGVKAVKAV ADIPVLAGAG 

       190        200        210        220 
ITYREDVVRA VQLGASGILL ASAVMKAADP DKALSEFVDA LSSVA

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References

[1]"The genome sequence of the crenarchaeon Acidilobus saccharovorans supports a new order, Acidilobales, and suggests an important ecological role in terrestrial acidic hot springs."
Mardanov A.V., Svetlitchnyi V.A., Beletsky A.V., Prokofeva M.I., Bonch-Osmolovskaya E.A., Ravin N.V., Skryabin K.G.
Appl. Environ. Microbiol. 76:5652-5657(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 16705 / VKM B-2471 / 345-15.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001742 Genomic DNA. Translation: ADL19635.1.
RefSeqYP_003816666.1. NC_014374.1.

3D structure databases

ProteinModelPortalD9Q2U7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADL19635; ADL19635; ASAC_1230.
GeneID9499485.
KEGGasc:ASAC_1230.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000223030.
KOK01803.
OMAIPVYAQH.

Enzyme and pathway databases

BioCycASAC666510:GH9G-1274-MONOMER.
UniPathwayUPA00109; UER00189.
UPA00138.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00147_A. TIM_A.
InterProIPR013785. Aldolase_TIM.
IPR008867. ThiG.
IPR000652. Triosephosphate_isomerase.
IPR022891. Triosephosphate_isomerase_arc.
[Graphical view]
PfamPF05690. ThiG. 1 hit.
PF00121. TIM. 1 hit.
[Graphical view]
SUPFAMSSF51351. Triophos_ismrse. 1 hit.
PROSITEPS51440. TIM_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD9Q2U7_ACIS3
AccessionPrimary (citable) accession number: D9Q2U7
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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