Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

D9Q2U7

- D9Q2U7_ACIS3

UniProt

D9Q2U7 - D9Q2U7_ACIS3

Protein

Triosephosphate isomerase

Gene

tpiA

Organism
Acidilobus saccharovorans (strain DSM 16705 / VKM B-2471 / 345-15)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (05 Oct 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    D-glyceraldehyde 3-phosphate = glycerone phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei9 – 91SubstrateUniRule annotation
    Binding sitei11 – 111SubstrateUniRule annotation
    Active sitei93 – 931ElectrophileUniRule annotation
    Active sitei141 – 1411Proton acceptorUniRule annotation

    GO - Molecular functioni

    1. 2-iminoacetate synthase activity Source: InterPro
    2. triose-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP
    3. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationImported

    Keywords - Biological processi

    GluconeogenesisUniRule annotation, GlycolysisUniRule annotation, Pentose shuntUniRule annotation

    Enzyme and pathway databases

    BioCyciASAC666510:GH9G-1274-MONOMER.
    UniPathwayiUPA00109; UER00189.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Triosephosphate isomeraseUniRule annotation (EC:5.3.1.1UniRule annotation)
    Short name:
    TIMUniRule annotation
    Alternative name(s):
    Triose-phosphate isomeraseUniRule annotation
    Gene namesi
    Name:tpiAUniRule annotation
    Ordered Locus Names:ASAC_1230Imported
    OrganismiAcidilobus saccharovorans (strain DSM 16705 / VKM B-2471 / 345-15)Imported
    Taxonomic identifieri666510 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiAcidilobalesAcidilobaceaeAcidilobus
    ProteomesiUP000000346: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD9Q2U7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the triosephosphate isomerase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000223030.
    KOiK01803.
    OMAiETWAQHV.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00147_A. TIM_A.
    InterProiIPR013785. Aldolase_TIM.
    IPR008867. ThiG.
    IPR000652. Triosephosphate_isomerase.
    IPR022891. Triosephosphate_isomerase_arc.
    [Graphical view]
    PANTHERiPTHR21139. PTHR21139. 1 hit.
    PfamiPF05690. ThiG. 1 hit.
    PF00121. TIM. 1 hit.
    [Graphical view]
    SUPFAMiSSF51351. SSF51351. 1 hit.
    PROSITEiPS51440. TIM_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D9Q2U7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRLVFAVNF KAYETAFNEK SLEIAREASK ASSRYGNVRV ILIVPAAIAS    50
    KVLQIYDDVY IEHADPVDYG AYTGYLPAKA ARLLGVRGIL VNHSEHKMIY 100
    RDVAKVVETA SKDGIETMAC ADTPGEAAGL AYLRPTYIAI EPPELIGTGV 150
    SVSKARPEVI TEGVKAVKAV ADIPVLAGAG ITYREDVVRA VQLGASGILL 200
    ASAVMKAADP DKALSEFVDA LSSVA 225
    Length:225
    Mass (Da):23,851
    Last modified:October 5, 2010 - v1
    Checksum:i7B826A75E692D6F8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001742 Genomic DNA. Translation: ADL19635.1.
    RefSeqiWP_013267147.1. NC_014374.1.
    YP_003816666.1. NC_014374.1.

    Genome annotation databases

    EnsemblBacteriaiADL19635; ADL19635; ASAC_1230.
    GeneIDi9499485.
    KEGGiasc:ASAC_1230.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001742 Genomic DNA. Translation: ADL19635.1 .
    RefSeqi WP_013267147.1. NC_014374.1.
    YP_003816666.1. NC_014374.1.

    3D structure databases

    ProteinModelPortali D9Q2U7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADL19635 ; ADL19635 ; ASAC_1230 .
    GeneIDi 9499485.
    KEGGi asc:ASAC_1230.

    Phylogenomic databases

    HOGENOMi HOG000223030.
    KOi K01803.
    OMAi ETWAQHV.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00189 .
    UPA00138 .
    BioCyci ASAC666510:GH9G-1274-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00147_A. TIM_A.
    InterProi IPR013785. Aldolase_TIM.
    IPR008867. ThiG.
    IPR000652. Triosephosphate_isomerase.
    IPR022891. Triosephosphate_isomerase_arc.
    [Graphical view ]
    PANTHERi PTHR21139. PTHR21139. 1 hit.
    Pfami PF05690. ThiG. 1 hit.
    PF00121. TIM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51351. SSF51351. 1 hit.
    PROSITEi PS51440. TIM_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the crenarchaeon Acidilobus saccharovorans supports a new order, Acidilobales, and suggests an important ecological role in terrestrial acidic hot springs."
      Mardanov A.V., Svetlitchnyi V.A., Beletsky A.V., Prokofeva M.I., Bonch-Osmolovskaya E.A., Ravin N.V., Skryabin K.G.
      Appl. Environ. Microbiol. 76:5652-5657(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 16705 / VKM B-2471 / 345-15Imported.

    Entry informationi

    Entry nameiD9Q2U7_ACIS3
    AccessioniPrimary (citable) accession number: D9Q2U7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 5, 2010
    Last sequence update: October 5, 2010
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3