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D9PYW1 (D9PYW1_METTM) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length451 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH2 groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation By similarity. HAMAP-Rule MF_00027

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis. HAMAP-Rule MF_00027

Sequence similarities

Belongs to the CobB/CobQ family. CobB subfamily. HAMAP-Rule MF_00027

Contains 1 GATase cobBQ-type domain. HAMAP-Rule MF_00027

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain247 – 435189GATase cobBQ-type By similarity HAMAP-Rule MF_00027

Sites

Active site3291Nucleophile By similarity HAMAP-Rule MF_00027
Active site4271 By similarity HAMAP-Rule MF_00027

Sequences

Sequence LengthMass (Da)Tools
D9PYW1 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 7512AEC76FD0310A

FASTA45149,539
        10         20         30         40         50         60 
MRLVLAGTGS AVGKTTIATG IMRALSDRGI QPFKVGPDYI DPSYHTMATG NVSRNLDSFF 

        70         80         90        100        110        120 
MTDAQIREAF TRAMKISGAR MGIIEGVRGL YEGISATGDT GSTASVAKAL KAPVVLIINS 

       130        140        150        160        170        180 
RSLVKSAAAM VLGFRSLDPE VKIRGVILNQ VKNRRHYLKT KEAIEKLTGT EVVGGIPRSA 

       190        200        210        220        230        240 
ELEVEQRHLG LVPAVEREQI ASYIEKWGSA MEEYLDLEAL EDIMASAGKI DGEREPLWRR 

       250        260        270        280        290        300 
ENKRKVKIGV AFDEAFNFYY RENIEALEDN AASVVYFSPL HDEELPDVDA VYIGGGYPEV 

       310        320        330        340        350        360 
FAGELESNRS MRISVRKFHA DGRPIFGECG GLMYLMNSID GHKMCGVFPY SAEMTKNVQG 

       370        380        390        400        410        420 
LSYVISEAVS DNLITEEGDV FRGHEFHYSR VSVTGDAQFA FRVLRGRGIM DSMDGITSGS 

       430        440        450 
ALASYVHIHA ASCPTFAANF TRNAWELQDE V

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Methanothermobacter marburgensis."
Kaster A., Seedorf H., Goenrich M., Wiezer A., Liesegang H., Thauer R., Gottschalk G.
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Marburg.
[2]"Complete genome sequence of Methanothermobacter marburgensis, a methanoarchaeon model organism."
Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H., Gottschalk G., Thauer R.K.
J. Bacteriol. 192:5850-5851(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001710 Genomic DNA. Translation: ADL57656.1.
RefSeqYP_003848969.1. NC_014408.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADL57656; ADL57656; MTBMA_c00460.
GeneID9703751.
KEGGmmg:MTBMA_c00460.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000289958.
KOK02224.
OMACWLPGGY.

Enzyme and pathway databases

BioCycMMAR79929:GH5J-46-MONOMER.
UniPathwayUPA00148.

Family and domain databases

HAMAPMF_00027. CobB.
InterProIPR004484. CbiA_synth.
IPR017929. CobB/CobQ_GATase.
IPR002586. CobQ/CobB/MinD/ParA_Nub-bd_dom.
IPR011698. GATase_3.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF01656. CbiA. 1 hit.
PF07685. GATase_3. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00379. cobB. 1 hit.
PROSITEPS51274. GATASE_COBBQ. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD9PYW1_METTM
AccessionPrimary (citable) accession number: D9PYW1
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 29, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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