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D9J2T9 (D9J2T9_MOMBA) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length246 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA. SAAS SAAS017989

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding70 – 712CDP PDB 4K6P
Nucleotide binding70 – 712CTP
Nucleotide binding109 – 1124CTP
Region69 – 713Kanamycin binding PDB 3U6T
Region70 – 712Ascorbic acid binding PDB 4JTP
Region108 – 1114Kanamycin binding PDB 3U6T

Sites

Binding site701Phosphate PDB 4JTB
Binding site851Beta-D-mannose PDB 4FZ9
Binding site851CDP PDB 4K6P
Binding site851CTP
Binding site851Kanamycin PDB 3U6T
Binding site1091CDP PDB 4K6P
Binding site1101Beta-D-mannose; via amide nitrogen PDB 4FZ9
Binding site1111Ascorbic acid PDB 4JTP
Binding site1631CDP PDB 4K6P
Binding site1631CTP
Binding site1631Kanamycin PDB 3U6T
Binding site1631Phosphate PDB 4JTB

Amino acid modifications

Glycosylation2271N-linked (GlcNAc...) PDB 3SJ6 PDB 3U8F PDB 4I47 PDB 4KPV PDB 3N1N PDB 3V2K PDB 4EMF PDB 3QJI PDB 4L66 PDB 4JTP PDB 3U70 PDB 3U6Z PDB 4FPZ PDB 3U6T PDB 4O4Q PDB 4LRO PDB 3V14 PDB 4KWN PDB 4KJH PDB 4K6S PDB 4K6Q PDB 4O0O PDB 4K6P PDB 4M5A PDB 4FZ9 PDB 3Q4P PDB 4FXA PDB 4K2Z PDB 4DWM PDB 3S9Q PDB 4GUW PDB 4HOA PDB 4H0Z PDB 4KMK PDB 4EMR PDB 4LWX PDB 4JTB PDB 4G2X PDB 4O8E PDB 4KL4 PDB 4F9N PDB 4LT4 PDB 3RL9

Experimental info

Non-terminal residue11 EMBL ADK23804.1
Non-terminal residue2461 EMBL ADK23804.1

Sequences

Sequence LengthMass (Da)Tools
D9J2T9 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 6B38879C004BB72D

FASTA24627,069
        10         20         30         40         50         60 
DVSFRLSGAD PSSYGMFIKD LRNALPHTEK VYNIPLLLPS VSGAGRYLLM HLFNYDGNTI 

        70         80         90        100        110        120 
TVAVDVTNVY IMGYLALTTS YFFNEPAADL ASQYVFRSAR RKITLPYSGN YERLQIAAGK 

       130        140        150        160        170        180 
PREKIPIGLP ALDTAISTLL HYDSTAAAGA LLVLIQTTAE AARFKYIEQQ IQERAYRDEV 

       190        200        210        220        230        240 
PSSATISLEN SWSGLSKQIQ LAQGNNGVFR TPTVLVDSKG NRVQITNVTS NVVTSNIQLL 


LNTKNI 

« Hide

References

[1]"Crystal structure of the complex of type I ribosome inactivating protein with 7n-methyl-8-hydroguanosine-5-p-diphosphate at 1.8 A resolution."
Kushwaha G.S., Yamini S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (DEC-2010) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[2]"Crystal structure of the complex of ribosome inactivating protein with 7-methylguanosine triphosphate at 1.75A resolution."
Kumar M., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JAN-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[3]"Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Bhushan A., Kaur P., Sharma S., Singh T.P.
Submitted (OCT-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) IN COMPLEX WITH KANAMYCIN, GLYCOSYLATION AT ASN-227.
[4]"Crystal structure of the complex of type I Ribosome inactivating protein in complex with Mycolic acid at 1.8 A resolution."
Yamini S., Pandey S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (OCT-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[5]"Crystal structure of type 1 ribosome inactivating protein complexed with adenine in low ionic solvent."
Pandey N., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (OCT-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[6]"Crystal structure of the complex of type I Ribosome inactivating protein complexed with Trehalose at 1.70 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (DEC-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[7]"Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states."
Kushwaha G.S., Pandey N., Sinha M., Singh S.B., Kaur P., Sharma S., Singh T.P.
Biochim. Biophys. Acta 1824:679-691(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[8]"Crystal structure of the complex of type I Ribosome inactivating protein with N-acetylglucosamine at 1.62 A resolution."
Yamini S., Pandey S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (FEB-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.62 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[9]"Crystal structure of the complex of type I Ribosome inactivating protein from Momordica balsamina with N7-methylated guanine at 2.65 A resolution."
Yamini S., Kushwaha G.S., Bhushan S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (MAY-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[10]"Crystal structure of Ribosome inactivating protein (RIP) from Momordica balsamina with Uracil at 1.7 Angstrom resolution."
Singh A., Pandey S., Singh N., Kushwaha G.S., Sinha M., Bhushan A., Kaur P., Sharma S., Singh T.P.
Submitted (JUN-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[11]"Crystal structure of Cytidine bound Ribosome inactivating protein from Momordica balsamina at 1.78 Angstrom resolution."
Singh A., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JUL-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.78 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[12]"Crystal structure of the complex of Ribosome inactivating protein from Momordica Balsamina with disaccharide, N-Acetylglucosamine (beta-1, 4) Mannose at 1.7 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JUL-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) IN COMPLEX WITH BETA-D-MANNOSE, GLYCOSYLATION AT ASN-227.
[13]"Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with N-acetyl arginine at 1.7 Angstrom resolution."
Singh A., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JUL-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[14]"Crystal structure of type 1 Ribosome inactivating protein from Momordica balsamina with lipopolysaccharide at 1.6 Angstrom resolution."
Singh A., Pandey S., Kushwaha G.S., Bhushan A., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (AUG-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[15]"Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with N-acetyl muramic acid at 2.0 Angstrom resolution."
Singh A., Pandey S., Kushwaha G.S., Sinha M., Bhushan A., Kaur P., Sharma S., Singh T.P.
Submitted (SEP-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[16]"Crystal structure of the complex of type 1 ribosome inactivating protein from Momordica Balsamina with B-D-galactopyranosyl-(1-4)-D-glucose at 2.0 A resolution."
Yamini S., Pandey N., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (OCT-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[17]"First structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina."
Kushwaha G.S., Yamini S., Kumar M., Sinha M., Kaur P., Sharma S., Singh T.P.
Proteins 81:896-905(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[18]"Crystal structure of Ribosome inactivating protein from Momordica balsamina complexed with Ascorbic acid at 1.85 Angstrom resolution."
Pandey S., Bhushan A., Singh A., Tyagi T.K., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (MAR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) IN COMPLEX WITH ASCORBIC ACID, GLYCOSYLATION AT ASN-227.
[19]"Crystal structure of Ribosome inactivating protein from Momordica balsamina complexed with phosphate ion at 1.71 Angstrom resolution."
Pandey S., Tyagi T.K., Singh A., Kushwaha G.S., Sinha M., Bhushan A., Kaur P., Sharma S., Singh T.P.
Submitted (MAR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.71 ANGSTROMS) IN COMPLEX WITH PHOSPHATE, GLYCOSYLATION AT ASN-227.
[20]"Crystal structure of the complex formed between Ribosome inactivating protein from Momordica balsamina and cytidine monophosphate at 1.80 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[21]"Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with cytidine diphosphate at 1.80 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH CDP, GLYCOSYLATION AT ASN-227.
[22]"Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with cytidine triphosphate at 2.0A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH CTP, GLYCOSYLATION AT ASN-227.
[23]"Crystal structure of the complex of type I Ribosome inactivating protein from Momordica balsamina with Methylethylamine at 1.80 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[24]"A new stabilizing water structure at the substrate binding site in ribosome inactivating protein from Momordica balsamina at 1.80 A resolution."
Yamini S., Pandey S., Singh A., Bhushan A., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (MAY-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[25]"Crystal structure of Ribosome Inactivating protein from Momordica balsamina at 1.65 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (MAY-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[26]"Crystal structure of Ribosome inactivating protein from Momordica balsamina complexed with Polyethylene glycol at 1.90 Angstrom resolution."
Pandey S., Tyagi T.K., Singh A., Bhushan A., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (MAY-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[27]"Crystal structure of the complex of ribosome inactivating protein from Momordica balsamina with cytosine at 1.98 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (MAY-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[28]"Crystal structure of the complex of ribosome inactivating protein from Momordica balsamina with Pyrimidine-2,4(1H,3H)-dione at 2.57 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (MAY-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.57 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[29]"Crystal structure of Ribosome inactivating protein from Momordica balsamina with highly ordered water structure in the substrate binding site."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JUN-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[30]"Crystal structure of arginine inhibited Ribosome inactivating protein from Momordica balsamina at 1.69 A resolution."
Yamini S., Pandey S., Bhushan S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JUL-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.69 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[31]"Crystal structure of spermidine inhibited Ribosome inactivating protein from Momordica balsamina."
Yamini S., Pandey S., Sinha M., Bhushan A., Kaur P., Sharma S., Singh T.P.
Submitted (JUL-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[32]"Crystal structure of the complex of Ribosome inactivating protein from Momordica Balsamina with peptidoglycan fragment at 1.78 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JUL-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.78 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[33]"Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina inhibited by asymmetric dimethyl arginine at 1.70 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Bhushan A., Kaur P., Sharma S., Singh T.P.
Submitted (AUG-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[34]"Crystal structure of the complex formed between type 1 ribosome inactivating protein and uridine diphosphate at 1.81 A resolution."
Yamini S., Pandey S., Bhushan A., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (DEC-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.81 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[35]"Crystal structure of the complex of type 1 Ribosome inactivating protein from Momordica balsamina with 5-fluorouracil at 2.59 A resolution."
Yamini S., Pandey S., Kushwaha G.S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (DEC-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.59 ANGSTROMS), GLYCOSYLATION AT ASN-227.
[36]"Crystal structure of the complex of type I ribosome inactivating protein from Momordica balsamina with uridine triphosphate at 2.0 A resolution."
Pandey S., Yamini S., Bhushan A., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (DEC-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS), GLYCOSYLATION AT ASN-227.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HM367595 mRNA. Translation: ADK23804.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3N1NX-ray2.23A1-246[»]
3Q4PX-ray1.80A1-246[»]
3QJIX-ray1.75A1-246[»]
3RL9X-ray1.90A1-246[»]
3S9QX-ray1.67A1-246[»]
3SJ6X-ray1.60A1-246[»]
3U6TX-ray1.85A1-246[»]
3U6ZX-ray1.70A1-246[»]
3U70X-ray2.00A1-246[»]
3U8FX-ray1.80A1-246[»]
3V14X-ray1.70A1-246[»]
3V2KX-ray2.07A1-246[»]
4DWMX-ray1.62A1-246[»]
4EMFX-ray1.77A1-246[»]
4EMRX-ray1.75A1-246[»]
4F9NX-ray2.65A1-246[»]
4FPZX-ray1.70A1-246[»]
4FXAX-ray1.70A1-246[»]
4FZ9X-ray1.70A1-246[»]
4G2XX-ray1.78A1-246[»]
4GUWX-ray1.60A1-246[»]
4H0ZX-ray2.00A1-246[»]
4HOAX-ray2.00A1-246[»]
4I47X-ray2.65A1-246[»]
4JTBX-ray1.71A1-246[»]
4JTPX-ray1.85A1-246[»]
4K2ZX-ray1.80A1-246[»]
4K6PX-ray1.80A1-246[»]
4K6QX-ray1.80A1-246[»]
4K6SX-ray2.00A1-246[»]
4KJHX-ray1.98A1-246[»]
4KL4X-ray1.90A1-246[»]
4KMKX-ray1.65A1-246[»]
4KPVX-ray2.57A1-246[»]
4KWNX-ray1.80A1-246[»]
4L66X-ray1.70A1-246[»]
4LROX-ray1.98A1-246[»]
4LT4X-ray1.69A1-246[»]
4LWXX-ray1.78A1-246[»]
4M5AX-ray1.70A1-246[»]
4O0OX-ray2.59A1-246[»]
4O4QX-ray1.81A1-246[»]
4O8EX-ray2.00A1-246[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.420.10. 1 hit.
4.10.470.10. 1 hit.
InterProIPR001574. Ribosome_inactivat_prot.
IPR017988. Ribosome_inactivat_prot_CS.
IPR016138. Ribosome_inactivat_prot_sub1.
IPR016139. Ribosome_inactivat_prot_sub2.
IPR017989. Ribosome_inactivat_prot_subgr.
[Graphical view]
PfamPF00161. RIP. 1 hit.
[Graphical view]
PRINTSPR00396. SHIGARICIN.
SUPFAMSSF56371. SSF56371. 1 hit.
PROSITEPS00275. SHIGA_RICIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceD9J2T9.

Entry information

Entry nameD9J2T9_MOMBA
AccessionPrimary (citable) accession number: D9J2T9
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: April 16, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)