D9IDV3 (D9IDV3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Transient receptor potential cation channel subfamily M member 1 Ensembl ENSP00000437849

Submitted name:
Transient receptor potential melastatin family isoform 1 splice variant EMBL ADJ52078.1

Gene names

Name:

TRPM1 EMBL ADJ52078.1 Ensembl ENSP00000437849

Organism

Homo sapiens (Human) [Reference proteome] EMBL ADJ52078.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1642 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	Transmembrane RuleBase RU003378
Molecular function	Ion channel RuleBase RU003378 Receptor EMBL ADJ52078.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ion channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D9IDV3 [UniParc]. Last modified October 5, 2010. Version 1. Checksum: 8FCF58496AF8504D	FASTA	1,642	186,545
	10 20 30 40 50 60 MSSFKRGSLK SSTSGSQKGQ KSWIEKTFCK RECIFVIPSM KDSNRCCCGQ FTNQHIPPLP 70 80 90 100 110 120 SATPSKNEEE SKQVETQPEK WSVAKHTQSY PTDSYGVLEF QGGGYSNKAM YIRVSYDTKP 130 140 150 160 170 180 DSLLHLMVKD WQLELPKLLI SVHGGLQNFE MQPKLKQVFG KGLIKAAMTT GAWIFTGGVS 190 200 210 220 230 240 TGVISHVGDA LKDHSSKSRG RVCAIGIAPW GIVENKEDLV GKDVTRVYQT MSNPLSKLSV 250 260 270 280 290 300 LNNSHTHFIL ADNGTLGKYG AEVKLRRLLE KHISLQKINT RLGQGVPLVG LVVEGGPNVV 310 320 330 340 350 360 SIVLEYLQEE PPIPVVICDG SGRASDILSF AHKYCEEGGI INESLREQLL VTIQKTFNYN 370 380 390 400 410 420 KAQSHQLFAI IMECMKKKEL VTVFRMGSEG QQDIEMAILT ALLKGTNVSA PDQLSLALAW 430 440 450 460 470 480 NRVDIARSQI FVFGPHWPPL GSLAPPTDSK ATEKEKKPPM ATTKGGRGKG KGKKKGKVKE 490 500 510 520 530 540 EVEEETDPRK IELLNWVNAL EQAMLDALVL DRVDFVKLLI ENGVNMQHFL TIPRLEELYN 550 560 570 580 590 600 TRLGPPNTLH LLVRDVKKSN LPPDYHISLI DIGLVLEYLM GGAYRCNYTR KNFRTLYNNL 610 620 630 640 650 660 FGPKRPKALK LLGMEDDEPP AKGKKKKKKK KEEEIDIDVD DPAVSRFQYP FHELMVWAVL 670 680 690 700 710 720 MKRQKMAVFL WQRGEESMAK ALVACKLYKA MAHESSESDL VDDISQDLDN NSKDFGQLAL 730 740 750 760 770 780 ELLDQSYKHD EQIAMKLLTY ELKNWSNSTC LKLAVAAKHR DFIAHTCSQM LLTDMWMGRL 790 800 810 820 830 840 RMRKNPGLKV IMGILLPPTI LFLEFRTYDD FSYQTSKENE DGKEKEEENT DANADAGSRK 850 860 870 880 890 900 GDEENEHKKQ RSIPIGTKIC EFYNAPIVKF WFYTISYLGY LLLFNYVILV RMDGWPSLQE 910 920 930 940 950 960 WIVISYIVSL ALEKIREILM SEPGKLSQKI KVWLQEYWNI TDLVAISTFM IGAILRLQNQ 970 980 990 1000 1010 1020 PYMGYGRVIY CVDIIFWYIR VLDIFGVNKY LGPYVMMIGK MMIDMLYFVV IMLVVLMSFG 1030 1040 1050 1060 1070 1080 VARQAILHPE EKPSWKLARN IFYMPYWMIY GEVFADQIDL YAMEINPPCG ENLYDEEGKR 1090 1100 1110 1120 1130 1140 LPPCIPGAWL TPALMACYLL VANILLVNLL IAVFNNTFFE VKSISNQVWK FQRYQLIMTF 1150 1160 1170 1180 1190 1200 HDRPVLPPPM IILSHIYIII MRLSGRCRKK REGDQEERDR GLKLFLSDEE LKRLHEFEEQ 1210 1220 1230 1240 1250 1260 CVQEHFREKE DEQQSSSDER IRVTSERVEN MSMRLEEINE RETFMKTSLQ TVDLRLAQLE 1270 1280 1290 1300 1310 1320 ELSNRMVNAL ENLAGIDRSD LIQARSRASS ECEATYLLRQ SSINSADGYS LYRYHFNGEE 1330 1340 1350 1360 1370 1380 LLFEDTSLST SPGTGVRKKT CSFRIKEEKD VKTHLVPECQ NSLHLSLGTS TSATPDGSHL 1390 1400 1410 1420 1430 1440 AVDDLKNAEE SKLGPDIGIS KEDDERQTDS KKEETISPSL NKTDVIHGQD KSDVQNTQLT 1450 1460 1470 1480 1490 1500 VETTNIEGTI SYPLEETKIT RYFPDETINA CKTMKSRSFV YSRGRKLVGG VNQDVEYSSI 1510 1520 1530 1540 1550 1560 TDQQLTTEWQ CQVQKITRSH STDIPYIVSE AAVQAEHKEQ FADMQDEHHV AEAIPRIPRL 1570 1580 1590 1600 1610 1620 SLTITDRNGM ENLLSVKPDQ TLGFPSLRSK SLHGHPRNVK SIQGKLDRSG HASSVSSLVI 1630 1640 VSGMTAEEKK VKKEKASTET EC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the DNA sequence and duplication history of human chromosome 15." Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C. Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"TRPM1 forms ion channels associated with melanin content in melanocytes." Oancea E., Vriens J., Brauchi S., Jun J., Splawski I., Clapham D.E. Sci. Signal. 2:RA21-RA21(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Oancea E. Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC009562 Genomic DNA. No translation available. AC090829 Genomic DNA. No translation available. HM135791 mRNA. Translation: ADJ52078.1.
IPI	IPI00385124.
RefSeq	NP_001238949.1. NM_001252020.1. NP_002411.3. NM_002420.5.
UniGene	Hs.155942. Hs.732541.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000542188; ENSP00000437849; ENSG00000134160.
GeneID	4308.
KEGG	hsa:4308.
UCSC	uc021sia.1. human.
Organism-specific databases
CTD	4308.
HGNC	HGNC:7146. TRPM1.
GenAtlas	Search...
Phylogenomic databases
KO	K04976.
OMA	TMKSRSF.
Family and domain databases
InterPro	IPR005821. Ion_trans_dom. [Graphical view]
Pfam	PF00520. Ion_trans. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	4308.
NextBio	16953.

Entry information

Entry name

D9IDV3_HUMAN

Accession

Primary (citable) accession number: D9IDV3

Entry history

Integrated into UniProtKB/TrEMBL:	October 5, 2010
Last sequence update:	October 5, 2010
Last modified:	May 29, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.