ID   D9IAI1_HUMAN            Unreviewed;       187 AA.
AC   D9IAI1;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 97.
DE   RecName: Full=Phosphatidylethanolamine-binding protein 1 {ECO:0000256|ARBA:ARBA00040856};
DE   AltName: Full=HCNPpp {ECO:0000256|ARBA:ARBA00043158};
GN   Name=HEL-S-34 {ECO:0000313|EMBL:ACJ13697.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:ADI99998.1};
RN   [1] {ECO:0000313|EMBL:ACJ13697.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Li J.Y., Wang H.Y., Liu F.J., Liu J.;
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADI99998.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Chao G.;
RT   "Cloning differentially expressed genes by SSH.";
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: HCNP may be involved in the function of the presynaptic
CC       cholinergic neurons of the central nervous system. HCNP increases the
CC       production of choline acetyltransferase but not acetylcholinesterase.
CC       Seems to be mediated by a specific receptor.
CC       {ECO:0000256|ARBA:ARBA00037110}.
CC   -!- SIMILARITY: Belongs to the phosphatidylethanolamine-binding protein
CC       family. {ECO:0000256|ARBA:ARBA00007091}.
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DR   EMBL; EU794643; ACJ13697.1; -; mRNA.
DR   EMBL; HM131449; ADI99998.1; -; mRNA.
DR   RefSeq; NP_002558.1; NM_002567.3.
DR   SMR; D9IAI1; -.
DR   IntAct; D9IAI1; 1.
DR   MEROPS; I51.002; -.
DR   Antibodypedia; 2171; 742 antibodies from 44 providers.
DR   DNASU; 5037; -.
DR   GeneID; 5037; -.
DR   KEGG; hsa:5037; -.
DR   CTD; 5037; -.
DR   VEuPathDB; HostDB:ENSG00000089220; -.
DR   HOGENOM; CLU_043994_5_0_1; -.
DR   OMA; LIYEQKC; -.
DR   OrthoDB; 3412953at2759; -.
DR   BioGRID-ORCS; 5037; 19 hits in 1123 CRISPR screens.
DR   ChiTaRS; PEBP1; human.
DR   GenomeRNAi; 5037; -.
DR   ExpressionAtlas; D9IAI1; baseline and differential.
DR   CDD; cd00866; PEBP_euk; 1.
DR   Gene3D; 3.90.280.10; PEBP-like; 1.
DR   InterPro; IPR008914; PEBP.
DR   InterPro; IPR036610; PEBP-like_sf.
DR   InterPro; IPR035810; PEBP_euk.
DR   InterPro; IPR001858; Phosphatidylethanolamine-bd_CS.
DR   PANTHER; PTHR11362:SF150; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; 1.
DR   PANTHER; PTHR11362; PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN; 1.
DR   Pfam; PF01161; PBP; 1.
DR   SUPFAM; SSF49777; PEBP-like; 1.
DR   PROSITE; PS01220; PBP; 1.
PE   2: Evidence at transcript level;
KW   Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW   Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900}.
SQ   SEQUENCE   187 AA;  21057 MW;  F1E9F17E2CD11C36 CRC64;
     MPVDLSKWSG PLSLQEVDEQ PQHPLHVTYA GAAVDELGKV LTPTQVKNRP TSISWDGLDS
     GKLYTLVLTD PDAPSRKDPK YREWHHFLVV NMKGNDISSG TVLSDYVGSG PPKGTGLHRY
     VWLVYEQDRP LKCDEPILSN RSGDHRGKFK VASFRKKYEL RAPVAGTCYQ AEWDDYVPKL
     YEQLSGK
//