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Protein

Aminomethyltransferase

Gene

VOLCADRAFT_107582

Organism
Volvox carteri (Green alga)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

  1. aminomethyltransferase activity Source: UniProtKB-EC
  2. transaminase activity Source: UniProtKB-KW

GO - Biological processi

  1. glycine catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Gene namesi
ORF Names:VOLCADRAFT_107582Imported
OrganismiVolvox carteri (Green alga)Imported
Taxonomic identifieri3067 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesVolvocaceaeVolvox
ProteomesiUP000001058 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

InParanoidiD8UF24.
KOiK00605.

Family and domain databases

Gene3Di2.40.30.110. 1 hit.
3.30.1360.120. 2 hits.
InterProiIPR006223. GCS_T.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamiPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006487. GcvT. 1 hit.
SUPFAMiSSF101790. SSF101790. 1 hit.
TIGRFAMsiTIGR00528. gcvT. 1 hit.

Sequencei

Sequence statusi: Complete.

D8UF24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSTRRLLTL LPQLGRAGAL RASEHASATG SLLFTRGFAD DANLKKTVLY
60 70 80 90 100
DFHVANGGKM VPFAGWSMPI QYKDSIMEST IFCRKNASLF DVSHMCGLTL
110 120 130 140 150
KGKDAIKFLE GLVVGDIAGL KDGTGSLSVF TNEQGGIIDD TVITKVNGQE
160 170 180 190 200
IYVVVNAGCR DKDLAHLDKH LQAAKSKGLD VALTVHDDRS LLALQGPAAK
210 220 230 240 250
DVLGALAPGV DLAAMYFSDF RTFDVAGIPC WVTRTGYTGE DGFEISVPST
260 270 280 290 300
HAVALAEKLT ASERVRLAGL GPRDSLRLEA GLCLYGNDLN ESLTPVEAGL
310 320 330 340 350
AWTIGKRRRE GFDFLGGDVI KKQLAEGVSK RRVGFVSSGA PARQHSVIST
360 370 380 390 400
PDGQVVGEVT SGAFSPCLKK NIAMGYVEKD FSKPGTQLKV EVRGKQNEAV
410 420
VTKMPFLPTP YYKRPEAAKK
Length:420
Mass (Da):45,040
Last modified:October 5, 2010 - v1
Checksum:i3BD75DAF6787EE0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL378391 Genomic DNA. Translation: EFJ41696.1.
RefSeqiXP_002957198.1. XM_002957152.1.

Genome annotation databases

GeneIDi9626693.
KEGGivcn:VOLCADRAFT_107582.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL378391 Genomic DNA. Translation: EFJ41696.1.
RefSeqiXP_002957198.1. XM_002957152.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9626693.
KEGGivcn:VOLCADRAFT_107582.

Phylogenomic databases

InParanoidiD8UF24.
KOiK00605.

Family and domain databases

Gene3Di2.40.30.110. 1 hit.
3.30.1360.120. 2 hits.
InterProiIPR006223. GCS_T.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamiPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006487. GcvT. 1 hit.
SUPFAMiSSF101790. SSF101790. 1 hit.
TIGRFAMsiTIGR00528. gcvT. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: f. Nagariensis / EveImported.

Entry informationi

Entry nameiD8UF24_VOLCA
AccessioniPrimary (citable) accession number: D8UF24
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: March 4, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.