ID   D8Q478_SCHCM            Unreviewed;       543 AA.
AC   D8Q478;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Glycoside hydrolase family 13 protein {ECO:0000313|EMBL:EFI96752.1};
DE   Flags: Fragment;
GN   ORFNames=SCHCODRAFT_108800 {ECO:0000313|EMBL:EFI96752.1};
OS   Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN   [1] {ECO:0000313|EMBL:EFI96752.1, ECO:0000313|Proteomes:UP000007431}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX   PubMed=20622885; DOI=10.1038/nbt.1643;
RA   Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA   de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA   Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA   Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA   Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA   Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA   Woesten H.A.B.;
RT   "Genome sequence of the model mushroom Schizophyllum commune.";
RL   Nat. Biotechnol. 28:957-963(2010).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|ARBA:ARBA00008061}.
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DR   EMBL; GL377306; EFI96752.1; -; Genomic_DNA.
DR   RefSeq; XP_003031655.1; XM_003031609.1.
DR   AlphaFoldDB; D8Q478; -.
DR   STRING; 578458.D8Q478; -.
DR   VEuPathDB; FungiDB:SCHCODRAFT_02689018; -.
DR   eggNOG; KOG0471; Eukaryota.
DR   HOGENOM; CLU_024572_2_0_1; -.
DR   InParanoid; D8Q478; -.
DR   OMA; MQYFEWN; -.
DR   OrthoDB; 2728918at2759; -.
DR   Proteomes; UP000007431; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd11318; AmyAc_bac_fung_AmyA; 1.
DR   Gene3D; 2.40.30.140; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR013776; A-amylase_thermo.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR43447; ALPHA-AMYLASE; 1.
DR   PANTHER; PTHR43447:SF49; ALPHA-AMYLASE; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   PIRSF; PIRSF001021; Alph-amls_thrmst; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:EFI96752.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007431}.
FT   DOMAIN          66..449
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
FT   REGION          13..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         543
FT                   /evidence="ECO:0000313|EMBL:EFI96752.1"
SQ   SEQUENCE   543 AA;  61503 MW;  69CA72DC030A44CD CRC64;
     MFSDLHKRFA NVFRPGHRRT QSAARPTGGG GATPAAAAPP PAAHHAAGPG LSRMRLGTED
     DPEQNPLMIE FFTWDALRDD MSWWQHLEQE LPEMARMGIT QVWIPPPNKA AAKTGRGYDA
     YDIWDLGEFD QKGMVRTRWG SKEELLRACR TAKQVKVDVI VDAVINHKLG ADRVETFPAV
     RVDTQNRLKE LSKVHEIEGW TAFDFPGRGD KVGFTSYTGL DWDQRTQQQG IYRIAGKGHH
     GWSRNVGTEF GNYDYLLGVD IDHRHPEVQE DFLRWGPWML ETLGAAGFRI DAAKHIDYKF
     MLQWITATRR NAQEPRMFCV CEFWSGDVKL ILPYIRAFKG EAVFFDVPLH MRLCEASRKR
     ERYDLRDLMS STLARLRPGD AVTFVDNHDT VEGMDLESWV EENFKIQAYA LILLRPEGYP
     CIFYGDLYPN KKCYNANTAA NLRRLIEARR LYAYGPVQDY NAGKNCIGFV RGGTGRHPGC
     VVLLSNRDEA GPLHTIRMNV GPARAGAIYR SYMTQGGEVQ IDAHGWGEFS CFANAVQVWV
     PAA
//