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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

SCHCODRAFT_54510

Organism
Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei125NADUniRule annotation1
Binding sitei150SubstrateUniRule annotation1
Binding sitei187NAD; via amide nitrogenUniRule annotation1
Active sitei238Proton acceptorUniRule annotation1
Binding sitei303NADUniRule annotation1
Binding sitei335NAD; via amide nitrogenUniRule annotation1
Binding sitei337NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 42NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:SCHCODRAFT_54510Imported
OrganismiSchizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus)Imported
Taxonomic identifieri578458 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesSchizophyllaceaeSchizophyllum
Proteomesi
  • UP000007431 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi578458.XP_003033511.1.

Structurei

3D structure databases

ProteinModelPortaliD8Q226.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 205NAD_Gly3P_dh_NInterPro annotationAdd BLAST174
Domaini227 – 378NAD_Gly3P_dh_CInterPro annotationAdd BLAST152

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni303 – 304Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.
InParanoidiD8Q226.
KOiK00006.
OrthoDBiEOG092C3ZQP.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
PfamiView protein in Pfam
PF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiView protein in PROSITE
PS00957. NAD_G3PDH. 1 hit.

Sequencei

Sequence statusi: Complete.

D8Q226-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPFITKFEP FEPTEFVVDK EAGTRSPAKL EKVAIVGSGS WGTALARVAA
60 70 80 90 100
INAANLEGFD DEVRMWVRER EVPGKGKLTD IINSTHQNER YLPNVELPEN
110 120 130 140 150
LVAVSDLKEV VKGATLLLFV VPHQFLPNVL KTLKEPGVID PRARAISAIK
160 170 180 190 200
GVDVELREDG ADIYTYPFVI EKELHIPCSA LGGANIALDV GKGEFCETTI
210 220 230 240 250
GVPSPKDAAL WHAVFDGPAF RVHPIEDVAG VSLSGALKNV VAMAAGFVDG
260 270 280 290 300
MGLGGNTKAA ILRHGLIEMS NFTLEFFPSA SPLTFSHHSA GMADLITTSF
310 320 330 340 350
GGRNRKCAEA FVRAKMEGKP KTFQQLEEEL LNGQKLQGVE TAREVFEFLQ
360 370 380
ARKRLDGYPL FEKVYRISFE GMDPKRMFED L
Length:381
Mass (Da):41,687
Last modified:October 5, 2010 - v1
Checksum:i5C699485C73BDE6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL377305 Genomic DNA. Translation: EFI98608.1.
RefSeqiXP_003033511.1. XM_003033465.1.

Genome annotation databases

EnsemblFungiiEFI98608; EFI98608; SCHCODRAFT_54510.
GeneIDi9596044.
KEGGiscm:SCHCODRAFT_54510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL377305 Genomic DNA. Translation: EFI98608.1.
RefSeqiXP_003033511.1. XM_003033465.1.

3D structure databases

ProteinModelPortaliD8Q226.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi578458.XP_003033511.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEFI98608; EFI98608; SCHCODRAFT_54510.
GeneIDi9596044.
KEGGiscm:SCHCODRAFT_54510.

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.
InParanoidiD8Q226.
KOiK00006.
OrthoDBiEOG092C3ZQP.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
PfamiView protein in Pfam
PF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiView protein in PROSITE
PS00957. NAD_G3PDH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD8Q226_SCHCM
AccessioniPrimary (citable) accession number: D8Q226
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: February 15, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.