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Protein

DNA ligase

Gene

SCHCODRAFT_53697

Organism
Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:SCHCODRAFT_53697Imported
OrganismiSchizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus)Imported
Taxonomic identifieri578458 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesSchizophyllaceaeSchizophyllum
ProteomesiUP000007431 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiD8Q0I4.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8Q0I4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQATPAPTEA PGSPQPSQTT ASQQPFPEQP YNTDTLPFHI LTAFFEKLQG
60 70 80 90 100
ERKQEKRRKL LNHWFNKWRE DNGPDLYPVL RLILPHRDRE RNVYGLKEKA
110 120 130 140 150
LAKLYIKVIP LNKNDPDAMR LLYWKKPTEK HASTCASSAA SGDFPTVLYE
160 170 180 190 200
VVSKRSSVTQ STLTIDDIND MLDQLADMSN KSEKQSKIIQ RLYNEATPEQ
210 220 230 240 250
QLWFARIILK DMNISVKETT VFAVFHPDAQ ALYNTCSDLK KVAWQLADPS
260 270 280 290 300
IRLHEDEKQV KLGQPFMPML CKRPMKRIED TAQEMDGSEF IIEEKLDGER
310 320 330 340 350
MQLHKMGNQY YYSSRKGKDY TYLYGSHVGA GSLTPYIAHR FHKQADSAIL
360 370 380 390 400
DGEMLVWDPI SGRNLPFGTL KTAALDQSKK QAAPRPCLKV FDLLYLNGKS
410 420 430 440 450
LIDKSTAFRK KNMRLVIEAL PGRIEFVDEF KGRTAQDIRE KMDEVMANRG
460 470 480 490 500
EGLVIKHPKS QYVLNGRNND WIKVKPEYMD NMGETVDVLV VAGNYGSGRR
510 520 530 540 550
SGGVSTLICA VFDDRNTGSF NENESKYATF VRVGSGLTYA DYMWLRAKNW
560 570 580 590 600
KTWDAKNSPT YLQTAKRSHE DKGDVYLEYE DTFILKVKAA EITPSDQYHV
610 620 630 640 650
RYTMRFPRAL SIREEMAPGD CMTASAVVEQ LKTAKKRKME TNKVSSTKKR
660 670 680 690 700
KVVKKKVEML PRFDGPDMKD VKEESDLFKG MKFVVISDPK ARTGEEDRKK
710 720 730 740 750
LMKLIRSHGG QCPQFAKDPA AIVVYNGTST PYDLQLIIRK DTNDVVRPQW
760 770 780 790 800
VMDCIAKGEL VPMEKKYFFF ATTARKETAE YGEDGGAESS GSVTQESSDD
810 820 830 840 850
EAAAETSQSS KKRKRAGKSA EPETQDKTAD EEKATPAPSK PKVDLDPGLA
860 870 880 890 900
AWLGYDEDDA AGVEDDAGEK DERGGRDDVE SDNDSDNQDV KDEEEEDDMA
910 920 930 940 950
FWFNEDDGDD SATATLPTQK TTQSTADTQK GDDAPTTQPE VKMGDDNAMH
960 970 980 990 1000
YDEELIFKYL CFYLDSPSNA RASGMSVKST AHEDEINESF EELRSKIESN
1010 1020 1030 1040 1050
GGRVVDLSEP KLTHVVLDKR DLSRRIDLMR RTSKPKRRHL VLTAYIDACL
1060
EENTLLDEDG ELGHA
Length:1,065
Mass (Da):120,578
Last modified:October 5, 2010 - v1
Checksum:iE93BF5EC34468B3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL377305 Genomic DNA. Translation: EFI97745.1.
RefSeqiXP_003032648.1. XM_003032602.1.

Genome annotation databases

GeneIDi9590663.
KEGGiscm:SCHCODRAFT_53697.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL377305 Genomic DNA. Translation: EFI97745.1.
RefSeqiXP_003032648.1. XM_003032602.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9590663.
KEGGiscm:SCHCODRAFT_53697.

Phylogenomic databases

InParanoidiD8Q0I4.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: H4-8 / FGSC 9210Imported.

Entry informationi

Entry nameiD8Q0I4_SCHCM
AccessioniPrimary (citable) accession number: D8Q0I4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: February 4, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.