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D8NZI3

- D8NZI3_RALSL

UniProt

D8NZI3 - D8NZI3_RALSL

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Protein

Isocitrate dehydrogenase [NADP]

Gene
icd, RPSI07_0976
Organism
Ralstonia solanacearum (Pseudomonas solanacearum)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciRSOL859657:GJJ9-981-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
ORF Names:RPSI07_0976Imported
OrganismiRalstonia solanacearum (Pseudomonas solanacearum)Imported
Taxonomic identifieri305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
ProteomesiUP000006858: Chromosome

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000021113.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8NZI3-1 [UniParc]FASTAAdd to Basket

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MYQHIKVPAG EKITVNQDFS LNVPDNPIIP YIEGDGTGFD ITPVMIKVVD    50
AAVAKAYAGK RKISWMEIYA GEKSTKVYGP DVWLPEETLQ VLKDYVVSIK 100
GPLTTPVGGG IRSLNVALRQ ELDLYVCLRP VRYFKGVPSP VREPEKTDMV 150
IFRENSEDIY AGIEWAAESE QAKKVIAFLR NEMGVKKIRF PETSGIGIKP 200
VSKEGTQRLV RKAIQYAIDN DKPSVTIVHK GNIMKFTEGG FRDWAYELAQ 250
KEFGAELIDG GPWCKFKNPK TGKDIIVKDA IADAFLQQIL LRPAEYSVVA 300
TLNLNGDYIS DALAAQVGGI GIAPGANLSD SVAMFEATHG TAPKYAGKDY 350
VNPGSEILSA EMMLRHMGWT EAADLIISSI EKSILSKKVT YDFARLLEGA 400
TQVSCSGFGQ VMIDNM 416
Length:416
Mass (Da):45,696
Last modified:October 5, 2010 - v1
Checksum:iCEBC39AEC915A5E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP885906 Genomic DNA. Translation: CBJ50336.1.

Genome annotation databases

EnsemblBacteriaiCBJ50336; CBJ50336; RPSI07_0976.
PATRICi42538081. VBIRalSol167236_2650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP885906 Genomic DNA. Translation: CBJ50336.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBJ50336 ; CBJ50336 ; RPSI07_0976 .
PATRICi 42538081. VBIRalSol167236_2650.

Phylogenomic databases

HOGENOMi HOG000021113.

Enzyme and pathway databases

BioCyci RSOL859657:GJJ9-981-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence."
    Remenant B., Coupat-Goutaland B., Guidot A., Cellier G., Wicker E., Allen C., Fegan M., Pruvost O., Elbaz M., Calteau A., Salvignol G., Mornico D., Mangenot S., Barbe V., Medigue C., Prior P.
    BMC Genomics 11:379-379(2010)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PSI07Imported.

Entry informationi

Entry nameiD8NZI3_RALSL
AccessioniPrimary (citable) accession number: D8NZI3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: November 13, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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