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D8NYZ2

- D8NYZ2_RALSL

UniProt

D8NYZ2 - D8NYZ2_RALSL

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Protein

Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE

Gene

ubiE

Organism
Ralstonia solanacearum (Pseudomonas solanacearum)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).UniRule annotation

Catalytic activityi

A demethylmenaquinone + S-adenosyl-L-methionine = a menaquinol + S-adenosyl-L-homocysteine.UniRule annotation
S-adenosyl-L-methionine + 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol = S-adenosyl-L-homocysteine + 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. methyltransferase activity Source: UniProtKB-KW

GO - Biological processi

  1. menaquinone biosynthetic process Source: UniProtKB-UniPathway
  2. ubiquinone biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Menaquinone biosynthesisUniRule annotation, Ubiquinone biosynthesisUniRule annotation

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciRSOL859657:GJJ9-2957-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiEUniRule annotation (EC:2.1.1.163UniRule annotation, EC:2.1.1.201UniRule annotation)
Alternative name(s):
2-methoxy-6-polyprenyl-1,4-benzoquinol methylaseUniRule annotation
Demethylmenaquinone methyltransferaseUniRule annotation
Gene namesi
Name:ubiEUniRule annotationImported
ORF Names:RPSI07_2911Imported
OrganismiRalstonia solanacearum (Pseudomonas solanacearum)Imported
Taxonomic identifieri305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
ProteomesiUP000006858: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD8NYZ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiE family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000249463.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01813. UbiE_methyltran.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR004033. UbiE/COQ5_MeTrFase.
IPR023576. UbiE/COQ5_MeTrFase_CS.
[Graphical view]
PfamiPF01209. Ubie_methyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR01934. MenG_MenH_UbiE. 1 hit.
PROSITEiPS51608. SAM_MT_UBIE. 1 hit.
PS01183. UBIE_1. 1 hit.
PS01184. UBIE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8NYZ2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSQTHFGFQQ VDEREKAGKV AGVFHSVASK YDVMNDLMSG GMHRLWKLFT
60 70 80 90 100
IAQAAVRPGY KVLDIAGGTG DLAKAFARQA GPTGEVWLTD INESMLRVGR
110 120 130 140 150
DRLLDAGVLT PTCLCDAEHI PFPNAYFDVV TVAFGLRNMT HKDRALAEMR
160 170 180 190 200
RVVKPGGKVM VLEFSKVWQP LERAYDLYSF KVLPWLGSKV AGDAESYRYL
210 220 230 240
AESIRMHPDQ ETLKQMMEQA GLDSVEYFNL TAGVVALHVG RRL
Length:243
Mass (Da):27,099
Last modified:October 5, 2010 - v1
Checksum:i98194B13B65125F7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP885906 Genomic DNA. Translation: CBJ52274.1.

Genome annotation databases

EnsemblBacteriaiCBJ52274; CBJ52274; RPSI07_2911.
PATRICi42541994. VBIRalSol167236_4565.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP885906 Genomic DNA. Translation: CBJ52274.1 .

3D structure databases

ProteinModelPortali D8NYZ2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBJ52274 ; CBJ52274 ; RPSI07_2911 .
PATRICi 42541994. VBIRalSol167236_4565.

Phylogenomic databases

HOGENOMi HOG000249463.

Enzyme and pathway databases

UniPathwayi UPA00232 .
BioCyci RSOL859657:GJJ9-2957-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01813. UbiE_methyltran.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR004033. UbiE/COQ5_MeTrFase.
IPR023576. UbiE/COQ5_MeTrFase_CS.
[Graphical view ]
Pfami PF01209. Ubie_methyltran. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR01934. MenG_MenH_UbiE. 1 hit.
PROSITEi PS51608. SAM_MT_UBIE. 1 hit.
PS01183. UBIE_1. 1 hit.
PS01184. UBIE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence."
    Remenant B., Coupat-Goutaland B., Guidot A., Cellier G., Wicker E., Allen C., Fegan M., Pruvost O., Elbaz M., Calteau A., Salvignol G., Mornico D., Mangenot S., Barbe V., Medigue C., Prior P.
    BMC Genomics 11:379-379(2010)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PSI07Imported.

Entry informationi

Entry nameiD8NYZ2_RALSL
AccessioniPrimary (citable) accession number: D8NYZ2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: October 29, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3