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Protein

Multidrug resistance protein MdtG

Gene

mdtG

Organism
Erwinia billingiae (strain Eb661)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Multidrug resistance protein MdtGUniRule annotation
Gene namesi
Name:mdtGUniRule annotation
Ordered Locus Names:EbC_16150
OrganismiErwinia billingiae (strain Eb661)
Taxonomic identifieri634500 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeErwinia
Proteomesi
  • UP000008793 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 37HelicalUniRule annotationAdd BLAST21
Transmembranei59 – 79HelicalUniRule annotationAdd BLAST21
Transmembranei92 – 112HelicalUniRule annotationAdd BLAST21
Transmembranei116 – 136HelicalUniRule annotationAdd BLAST21
Transmembranei147 – 167HelicalUniRule annotationAdd BLAST21
Transmembranei174 – 194HelicalUniRule annotationAdd BLAST21
Transmembranei222 – 242HelicalUniRule annotationAdd BLAST21
Transmembranei257 – 277HelicalUniRule annotationAdd BLAST21
Transmembranei291 – 311HelicalUniRule annotationAdd BLAST21
Transmembranei320 – 340HelicalUniRule annotationAdd BLAST21
Transmembranei379 – 399HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004145791 – 411Multidrug resistance protein MdtGAdd BLAST411

Interactioni

Protein-protein interaction databases

STRINGi634500.EbC_16150.

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiRITPREG.
OrthoDBiPOG091H029Y.

Family and domain databases

CDDicd06174. MFS. 1 hit.
HAMAPiMF_01528. MFS_MdtG. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8MQN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATADVPLSS INWQKNLFVA WCGCFLTGIA FSLVMPFLPL YVELLGVTDP
60 70 80 90 100
HSLNMWSGLV FSITFLFSAI ASPFWGGLAD RKGRKIMLLR SALGMSVVMV
110 120 130 140 150
LMGLATSIWQ FLALRAVLGL LGGFVPNANA LIATQVPRNK SGWALGWLST
160 170 180 190 200
GAVSGALIGP LIGGLLADSF GLRPVFFITA SVLFVCFIMT LFAVREEFVP
210 220 230 240 250
VQKKDMLHAH QVFTTLKNPR LVLTLFVTTM IIQVATGSIA PILTLYVRDL
260 270 280 290 300
AGDIQNLAFV SGLIASVPGV AALISAPRLG KLGDRIGPER ILVAMLLVSV
310 320 330 340 350
LLLIPMSMVQ NPLQLGILRF LLGAADGALL PAVQTLLIYN ASNQVAGRIF
360 370 380 390 400
SYNQSFRDIG NVTGPLMGAA VSAHWGFRAV FVVTACVVLF NAIYSWITLR
410
RRVDRSSMLD E
Length:411
Mass (Da):44,313
Last modified:October 5, 2010 - v1
Checksum:iA675EF4A7D092751
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP236843 Genomic DNA. Translation: CAX59146.1.
RefSeqiWP_013201639.1. NC_014306.1.

Genome annotation databases

EnsemblBacteriaiCAX59146; CAX59146; EbC_16150.
KEGGiebi:EbC_16150.
PATRICi42306216. VBIErwBil95213_1947.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP236843 Genomic DNA. Translation: CAX59146.1.
RefSeqiWP_013201639.1. NC_014306.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi634500.EbC_16150.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAX59146; CAX59146; EbC_16150.
KEGGiebi:EbC_16150.
PATRICi42306216. VBIErwBil95213_1947.

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiRITPREG.
OrthoDBiPOG091H029Y.

Family and domain databases

CDDicd06174. MFS. 1 hit.
HAMAPiMF_01528. MFS_MdtG. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMDTG_ERWBE
AccessioniPrimary (citable) accession number: D8MQN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: October 5, 2010
Last modified: November 2, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.