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D8MKK6 (D8MKK6_ERWBE) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339
Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339 EMBL CAX57662.1
Ordered Locus Names:EbC_01310 EMBL CAX57662.1
OrganismErwinia billingiae (strain Eb661) [Complete proteome] [HAMAP]
Taxonomic identifier634500 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Erwinia ›

Protein attributes

Sequence length320 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339 SAAS SAAS012828

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339 SAAS SAAS012828

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339 SAAS SAAS012828.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding22 – 265ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding155 – 1595ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding172 – 18817ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1281Proton acceptor By similarity HAMAP-Rule MF_00339
Metal binding1861Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00339
Metal binding1881Magnesium By similarity HAMAP-Rule MF_00339
Binding site1631Substrate By similarity HAMAP-Rule MF_00339
Binding site2441Substrate By similarity HAMAP-Rule MF_00339
Binding site2501Substrate By similarity HAMAP-Rule MF_00339
Binding site2531Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
D8MKK6 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 3E521D37B2901DC5

FASTA32034,942
        10         20         30         40         50         60 
MIKKIGVLTS GGDAPGMNAA IRGVVRAALS EGLEVCGVYD GYLGLYEDRM ANLDRYSVSD 

        70         80         90        100        110        120 
MINRGGTFLG SARFPEFREE SVRTVCIENM KKRGIDALVV IGGDGSYMGA KRLTEMGFPC 

       130        140        150        160        170        180 
IGLPGTIDND VAGTDYTIGY FTALETVVEA IDRLRDTSSS HQRISIVEVM GRYCGDLTLA 

       190        200        210        220        230        240 
AAIAGGCEFI VLPEIPYTRE ELVEEIKAGI AKGKKHAIVA ITEHICDIDE LAKYIEAETK 

       250        260        270        280        290        300 
RETRSTVLGH IQRGGAPVAY DRILASRMGA YSIELLLQGY GGRCVGIQNE KMVHHDIIDA 

       310        320 
IENMKRPFKG DWLDTAKKLY

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References

[1]"Genome comparison of the epiphytic bacteria Erwinia billingiae and E. tasmaniensis with the pear pathogen E. pyrifoliae."
Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H., Knaust F., Geider K., Reinhardt R.
BMC Genomics 11:393-393(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Eb661 EMBL CAX57662.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FP236843 Genomic DNA. Translation: CAX57662.1.
RefSeqYP_003739522.1. NC_014306.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAX57662; CAX57662; EbC_01310.
GeneID9427768.
KEGGebi:EbC_01310.
PATRIC42303018. VBIErwBil95213_0394.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000248870.
KOK00850.

Enzyme and pathway databases

BioCycEBIL634500:GHYX-135-MONOMER.
UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012828. PFKA_ATP.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. Ppfruckinase. 1 hit.
TIGRFAMsTIGR02482. PFKA_ATP. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD8MKK6_ERWBE
AccessionPrimary (citable) accession number: D8MKK6
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 29, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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