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D8MCT0 (D8MCT0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Leucine-rich repeat-containing G-protein-coupled receptor 5 Ensembl ENSP00000443033
Gene names
Name:LGR5 EMBL CBL95002.2 Ensembl ENSP00000443033
OrganismHomo sapiens (Human) [Reference proteome] EMBL CBL95002.2
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length835 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Sequences

Sequence LengthMass (Da)Tools
D8MCT0 [UniParc].

Last modified October 5, 2010. Version 1.
Checksum: 352096C4523C1E2F

FASTA83592,006
        10         20         30         40         50         60 
MDTSRLGVLL SLPVLLQLAT GGSSPRSGVL LRGCPTHCHC EPDGRMLLRV DCSDLGLSEL 

        70         80         90        100        110        120 
PSNLSVFTSY LDLSMNNISQ LLPNPLPSLR FLEELRLAGN ALTYIPKGAF TGLYSLKVLM 

       130        140        150        160        170        180 
LQNNQLRHVP TEALQNLRSL QSLHLHNNRI HSLGKKCFDG LHSLETLDLN YNNLDEFPTA 

       190        200        210        220        230        240 
IRTLSNLKEL GFHSNNIRSI PEKAFVGNPS LITIHFYDNP IQFVGRSAFQ HLPELRTLTL 

       250        260        270        280        290        300 
NGASQITEFP DLTGTANLES LTLTGAQISS LPQTVCNQLP NLQVLDLSYN LLEDLPSFSV 

       310        320        330        340        350        360 
CQKLQKIDLR HNEIYEIKVD TFQQLLSLRS LNLAWNKIAI IHPNAFSTLP SLIKLDLSSN 

       370        380        390        400        410        420 
LLSSFPITGL HGLTHLKLTG NHALQSLISS ENFPELKVIE MPYAYQCCAF GVCENAYKIS 

       430        440        450        460        470        480 
NQWNKGDNSS MDDLHKKDAG MFQAQDERDL EDFLLDFEED LKALHSVQCS PSPGPFKPCE 

       490        500        510        520        530        540 
HLLDGWLIRI GVWTIAVLAL TCNALVTSTV FRSPLYISPI KLLIGVIAAV NMLTGVSSAV 

       550        560        570        580        590        600 
LAGVDAFTFG SFARHGAWWE NGVGCHVIGF LSIFASESSV FLLTLAALER GFSVKYSAKF 

       610        620        630        640        650        660 
ETKAPFSSLK VIILLCALLA LTMAAVPLLG GSKYGASPLC LPLPFGEPST MGYMVALILL 

       670        680        690        700        710        720 
NSLCFLMMTI AYTKLYCNLD KGDLENIWDC SMVKHIALLL FTNCILNCPV AFLSFSSLIN 

       730        740        750        760        770        780 
LTFISPEVIK FILLVVVPLP ACLNPLLYIL FNPHFKEDLV SLRKQTYVWT RSKHPSLMSI 

       790        800        810        820        830 
NSDDVEKQSC DSTQALVTFT SSSITYDLPP SSVPSPAYPV TESCHLSSVA FVPCL 

« Hide

References

« Hide 'large scale' references
[1]"The finished DNA sequence of human chromosome 12."
Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R. expand/collapse author list , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Alternatively spliced transcript of the GPR49-mRNA occur in different tumor cell lines and soft tissue sarcoma."
Rot S., Taubert H., Bache M., Vordermark D., Kappler M.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC078860 Genomic DNA. No translation available.
AC090116 Genomic DNA. No translation available.
FN820440 mRNA. Translation: CBL95002.2.
RefSeqNP_001264156.1. NM_001277227.1.
UniGeneHs.658889.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000536515; ENSP00000443033; ENSG00000139292.
GeneID8549.
KEGGhsa:8549.
UCSCuc021rar.2. human.

Organism-specific databases

CTD8549.
HGNCHGNC:4504. LGR5.
GenAtlasSearch...

Phylogenomic databases

KOK04308.

Family and domain databases

Gene3D1.20.1070.10. 1 hit.
InterProIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002131. Gphrmn_rcpt_fam.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR000372. LRR-contain_N.
[Graphical view]
PfamPF00001. 7tm_1. 1 hit.
PF00560. LRR_1. 2 hits.
PF01462. LRRNT. 1 hit.
[Graphical view]
PRINTSPR00373. GLYCHORMONER.
PR00237. GPCRRHODOPSN.
SMARTSM00369. LRR_TYP. 6 hits.
SM00013. LRRNT. 1 hit.
[Graphical view]
PROSITEPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
PS51450. LRR. 12 hits.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi8549.
NextBio35495810.

Entry information

Entry nameD8MCT0_HUMAN
AccessionPrimary (citable) accession number: D8MCT0
Entry history
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: April 16, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.