D8KCN3 (D8KCN3_LACLN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr
Ordered Locus Names:	LLNZ_08785

Organism

Lactococcus lactis subsp. cremoris (strain NZ9000) [Complete proteome] [HAMAP]

Taxonomic identifier

746361 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Lactococcus › Lactococcus lactis › Lactococcus lactis subsp. cremoris

Protein attributes

Sequence length	367 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622 RuleBase RU004247
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate SAAS SAAS020622 RuleBase RU000608
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622 EMBL ADJ60689.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D8KCN3 [UniParc]. Last modified October 5, 2010. Version 1. Checksum: B6DE1496315FA814	FASTA	367	40,677
	10 20 30 40 50 60 MKTSPHRNTS AIVDLKAIRN NIEKFKKHIN PNAEIWPAVK ADAYGHGSIE VSKAVSDLVG 70 80 90 100 110 120 GFCVSNLDEA IELRNHLVTK PILVLSGIVP EDVDIAAALN ISLTAPSLEW LKLVVQEEAE 130 140 150 160 170 180 LSDLKIHIGV DSGMGRIGIR DVEEANQMIE LADKYAINFE GIFTHFATAD MADETKFKNQ 190 200 210 220 230 240 QARFNKIMAG LSRQPKFIHS TNTAAALWHK EQVQAIERLG ISMYGLNPSG KTLELPFEIE 250 260 270 280 290 300 PALSLVSELT HIKKIAAGET VGYGATYETS EETWIGTVPI GYADGWTRQM QGFKVLVDGK 310 320 330 340 350 360 FCEIVGRVCM DQMMIKLDKS YPLGTKVTLI GRDKANEITT TDVADWRGTI NYEVLCLLSD RIKRIYK

References

[1]	"Genome sequences of Lactococcus lactis MG1363 (revised) and NZ9000 and comparative physiological studies." Linares D.M., Kok J., Poolman B. J. Bacteriol. 192:5806-5812(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NZ9000.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002094 Genomic DNA. Translation: ADJ60689.1.
RefSeq	YP_006357111.1. NC_017949.1.
3D structure databases
ProteinModelPortal	D8KCN3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADJ60689; ADJ60689; LLNZ_08785.
GeneID	13020338.
KEGG	lln:LLNZ_08785.
PATRIC	43096986. VBILacLac151604_1768.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D8KCN3_LACLN

Accession

Primary (citable) accession number: D8KCN3

Entry history

Integrated into UniProtKB/TrEMBL:	October 5, 2010
Last sequence update:	October 5, 2010
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)