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D8KAW1

- D8KAW1_NITWC

UniProt

D8KAW1 - D8KAW1_NITWC

Protein

Ribulose bisphosphate carboxylase large chain

Gene

cbbL

Organism
Nitrosococcus watsoni (strain C-113)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (05 Oct 2010)
      Previous versions | rss
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    Functioni

    RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

    Catalytic activityi

    2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
    3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

    Cofactori

    Binds 1 magnesium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei131 – 1311Substrate; in homodimeric partnerUniRule annotation
    Binding sitei181 – 1811SubstrateUniRule annotation
    Active sitei183 – 1831Proton acceptorUniRule annotation
    Binding sitei185 – 1851SubstrateUniRule annotation
    Metal bindingi209 – 2091Magnesium; via carbamate groupUniRule annotation
    Metal bindingi211 – 2111MagnesiumUniRule annotation
    Metal bindingi212 – 2121MagnesiumUniRule annotation
    Active sitei301 – 3011Proton acceptorUniRule annotation
    Binding sitei302 – 3021SubstrateUniRule annotation
    Binding sitei334 – 3341SubstrateUniRule annotation
    Sitei341 – 3411Transition state stabilizerUniRule annotation
    Binding sitei386 – 3861SubstrateUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. monooxygenase activity Source: UniProtKB-KW
    3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. reductive pentose-phosphate cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

    Keywords - Biological processi

    Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciNWAT105559:GHXU-2821-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
    Short name:
    RuBisCO large subunitUniRule annotation
    Gene namesi
    Name:cbbLUniRule annotation
    Ordered Locus Names:Nwat_2772Imported
    OrganismiNitrosococcus watsoni (strain C-113)Imported
    Taxonomic identifieri105559 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus
    ProteomesiUP000000393: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei209 – 2091N6-carboxylysineUniRule annotation

    Interactioni

    Subunit structurei

    Heterohexadecamer of 8 large chains and 8 small chains.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD8KAW1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

    Phylogenomic databases

    KOiK01601.
    OMAiCTPLKQA.

    Family and domain databases

    Gene3Di3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPiMF_01338. RuBisCO_L_type1.
    InterProiIPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view]
    PfamiPF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D8KAW1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGKSETMAEG KERYQSGVIP YKKMGYWEPD YQPKETDIIA MFRITPQPGV    50
    DPEEAAAAVA GESSTATWTV VWTDRLTACE LYRAKAYRID PVPNTGEGTK 100
    NEAQYFAYIA YDLDLFEPGS IANLTASIIG NVFGFKAVKA LRLEDMRIPV 150
    AYLKTFQGPA TGVVVERERL DKFGRPLLGA TTKPKLGLSG RNYGRVVYEA 200
    LKGGLDFVKD DENINSQPFM HWRDRFLYCM EAVNKASAAT GEVKGHYLNV 250
    TAATMEDMYE RAEFAKSLGS VIIMIDLVVG YTAIQSMAKW ARKNDMILHL 300
    HRAGNSTYSR QKNHGMNFRV ICKWMRMAGV DHIHAGTVVG KLEGDPLMIK 350
    GFYDTLLDSH TPTSLEHGLF FDQDWASLNK VMPVASGGIH AGQMHQLIQY 400
    LGEDVILQFG GGTIGHPQGI QAGAVANRVA LEAMILARNE GRDYVKEGPQ 450
    ILQDAAKWCS PLKAALDTWK DVTFNYESTD TADFVPTATA SV 492
    Length:492
    Mass (Da):54,425
    Last modified:October 5, 2010 - v1
    Checksum:i2ED50814934759BE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002086 Genomic DNA. Translation: ADJ29538.1.
    RefSeqiYP_003761859.1. NC_014315.1.

    Genome annotation databases

    EnsemblBacteriaiADJ29538; ADJ29538; Nwat_2772.
    GeneIDi9394269.
    KEGGinwa:Nwat_2772.
    PATRICi42238239. VBINitWat28885_2971.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002086 Genomic DNA. Translation: ADJ29538.1 .
    RefSeqi YP_003761859.1. NC_014315.1.

    3D structure databases

    ProteinModelPortali D8KAW1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADJ29538 ; ADJ29538 ; Nwat_2772 .
    GeneIDi 9394269.
    KEGGi nwa:Nwat_2772.
    PATRICi 42238239. VBINitWat28885_2971.

    Phylogenomic databases

    KOi K01601.
    OMAi CTPLKQA.

    Enzyme and pathway databases

    BioCyci NWAT105559:GHXU-2821-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPi MF_01338. RuBisCO_L_type1.
    InterProi IPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view ]
    Pfami PF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Nitrosococcus watsoni C-113."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Malfatti S.A., Chain P.S.G., Land M., Hauser L., Kyrpides N., Ivanova N., Cambell M.A., Heidelberg J.F., Klotz M.G., Woyke T.
      Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C-113Imported.

    Entry informationi

    Entry nameiD8KAW1_NITWC
    AccessioniPrimary (citable) accession number: D8KAW1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 5, 2010
    Last sequence update: October 5, 2010
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Miscellaneous

    The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3