ID   D8K627_NITWC            Unreviewed;       456 AA.
AC   D8K627;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN   OrderedLocusNames=Nwat_1444 {ECO:0000313|EMBL:ADJ28354.1};
OS   Nitrosococcus watsoni (strain C-113).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC   Nitrosococcus.
OX   NCBI_TaxID=105559 {ECO:0000313|EMBL:ADJ28354.1, ECO:0000313|Proteomes:UP000000393};
RN   [1] {ECO:0000313|EMBL:ADJ28354.1, ECO:0000313|Proteomes:UP000000393}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C-113 {ECO:0000313|EMBL:ADJ28354.1,
RC   ECO:0000313|Proteomes:UP000000393};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Malfatti S.A., Chain P.S.G., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Cambell M.A., Heidelberg J.F., Klotz M.G., Woyke T.;
RT   "Complete sequence of chromosome of Nitrosococcus watsoni C-113.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC       ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP002086; ADJ28354.1; -; Genomic_DNA.
DR   AlphaFoldDB; D8K627; -.
DR   STRING; 105559.Nwat_1444; -.
DR   KEGG; nwa:Nwat_1444; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_3_1_6; -.
DR   OrthoDB; 9812625at2; -.
DR   Proteomes; UP000000393; Chromosome.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR   PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PIRSF; PIRSF036492; ALDH; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|PIRNR:PIRNR036492}.
FT   DOMAIN          20..427
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        209
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU10007"
FT   ACT_SITE        243
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ   SEQUENCE   456 AA;  52079 MW;  86A1FBE96550EE17 CRC64;
     MTDFRPLMRA FFSAGNTRNY AFRRQQLQSL HRLIFEHEEE IIRVLAADFG KPTAETYASE
     IAFLYQEINH TLKHLRNWMR PKKVSTPLVL QPSKSRIYFE PKGVVLVVGP WNYPFQLTLA
     PVVAAMAAGN CVVIKPSELT PQTSALIKHL INNYFSPEYL VVVEGEGAQI VPELIDKYHF
     DHIFFTGSTR VGAMIAEQAG RHLISTTLEL GGKSPAIVER SATFEVAARR LLWGKFFNSG
     QTCVAPDYLL LDEEIADSFI EILKNNLLKF YDDPSQASRH LARIVGKERW KTLVGYLEQG
     KILYGGQYNE ERLYIAPTLL QVTDLSQSVM QEEIFGPILP IITYQNCSEA LEIIERNPYP
     LAFYLFTREK KKQNWYLEHV QFGGGAINNA MVHLSNPNLP FGGINQSGHG RYHGYEGFSA
     FSNHKSVLHS DTWFDPDFKY PPYSKTTLKW FRRLLG
//