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Protein

Argininosuccinate lyase

Gene

argH

Organism
Dehalogenimonas lykanthroporepellens (strain ATCC BAA-1523 / JCM 15061 / BL-DC-9)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

  1. argininosuccinate lyase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process via ornithine Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciDLYK552811:GH8P-968-MONOMER.
UniPathwayiUPA00068; UER00114.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate lyaseUniRule annotationSAAS annotation (EC:4.3.2.1UniRule annotationSAAS annotation)
Short name:
ASALUniRule annotation
Alternative name(s):
ArginosuccinaseUniRule annotation
Gene namesi
Name:argHUniRule annotation
Ordered Locus Names:Dehly_0933Imported
OrganismiDehalogenimonas lykanthroporepellens (strain ATCC BAA-1523 / JCM 15061 / BL-DC-9)Imported
Taxonomic identifieri552811 [NCBI]
Taxonomic lineageiBacteriaChloroflexiDehalococcoidiaDehalogenimonas
ProteomesiUP000002349: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD8K0V7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000242744.
KOiK01755.
OMAiATDFRLW.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
HAMAPiMF_00006. Arg_succ_lyase.
InterProiIPR029419. Arg_succ_lyase_C.
IPR009049. Argininosuccinate_lyase.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PTHR11444:SF3. PTHR11444:SF3. 1 hit.
PfamiPF14698. ASL_C2. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00838. argH. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D8K0V7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHVRSRFDK SADDLVIDYS SSLPFDRRLY REDIRGSIAH TRMLSDRGII
60 70 80 90 100
PSADAEAIIR GLEEIEREIN NGSFEFKPVM EDIHMAVEAR LKEKIGEPAG
110 120 130 140 150
RLHTARSRND QVATDLRLYL KDTMEETLSE ISQLQRALLS QAEDNPEVIL
160 170 180 190 200
PGYTHLQPAQ PVLLAHHLLA YFEMLDRDKS RLADCYRRTD VLPLGSGALA
210 220 230 240 250
GTAYDTDREA VARELGFKEI SRNSLDAVSD RDFIIEFLAA AAIIMTHLSR
260 270 280 290 300
LAEELIIWSG AEFGFVEMDD AYATGSSIMP QKKNPDVAEL GRGKTGRVYG
310 320 330 340 350
HLTAMLTTMK GLPLAYNRDL QEDKEGLFDT VDTLLPSLRV FAGMVSTMRF
360 370 380 390 400
RPEQMLKSVD KSFILATDLA DYLVARGETF RNAHGAVGRL VNYCIGQGKM
410 420 430 440 450
FPDLTLEEYR QFSPLFGNDV MEVTVMTSVD ARNNPGGTAR CRVSQALKEA

QARLADS
Length:457
Mass (Da):51,078
Last modified:October 5, 2010 - v1
Checksum:i92F3E17F04F1E5B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002084 Genomic DNA. Translation: ADJ26235.1.
RefSeqiWP_013218379.1. NC_014314.1.
YP_003758556.1. NC_014314.1.

Genome annotation databases

EnsemblBacteriaiADJ26235; ADJ26235; Dehly_0933.
GeneIDi9390641.
KEGGidly:Dehly_0933.
PATRICi42250245. VBIDehLyk78720_0977.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002084 Genomic DNA. Translation: ADJ26235.1.
RefSeqiWP_013218379.1. NC_014314.1.
YP_003758556.1. NC_014314.1.

3D structure databases

ProteinModelPortaliD8K0V7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADJ26235; ADJ26235; Dehly_0933.
GeneIDi9390641.
KEGGidly:Dehly_0933.
PATRICi42250245. VBIDehLyk78720_0977.

Phylogenomic databases

HOGENOMiHOG000242744.
KOiK01755.
OMAiATDFRLW.

Enzyme and pathway databases

UniPathwayiUPA00068; UER00114.
BioCyciDLYK552811:GH8P-968-MONOMER.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
HAMAPiMF_00006. Arg_succ_lyase.
InterProiIPR029419. Arg_succ_lyase_C.
IPR009049. Argininosuccinate_lyase.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PTHR11444:SF3. PTHR11444:SF3. 1 hit.
PfamiPF14698. ASL_C2. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00838. argH. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Dehalogenimonas lykanthroporepellens BL-DC-9."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Daligault H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Rainey F.A., Yan J., da Costa M.S., Moe W.M., Woyke T.
    Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1523 / JCM 15061 / BL-DC-9Imported.

Entry informationi

Entry nameiD8K0V7_DEHLB
AccessioniPrimary (citable) accession number: D8K0V7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 5, 2010
Last sequence update: October 5, 2010
Last modified: March 4, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.