D8IXA0 (D8IXA0_HERSS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Homoserine kinase HAMAP-Rule MF_00301
Short name=HK HAMAP-Rule MF_00301
Short name=HSK HAMAP-Rule MF_00301
EC=2.7.1.39 HAMAP-Rule MF_00301

Gene names

Name:	thrB HAMAP-Rule MF_00301
Ordered Locus Names:	Hsero_0450

Organism

Herbaspirillum seropedicae (strain SmR1) [Complete proteome] [HAMAP] EMBL ADJ61975.1

Taxonomic identifier

757424 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Oxalobacteraceae › Herbaspirillum › Herbaspirillum seropedicae

Protein attributes

Sequence length	318 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP-Rule MF_00301 SAAS SAAS005280
Pathway	Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP-Rule MF_00301 SAAS SAAS005280
Sequence similarities	Belongs to the pseudomonas-type ThrB family. HAMAP-Rule MF_00301

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Threonine biosynthesis HAMAP-Rule MF_00301 SAAS SAAS005280
Ligand	ATP-binding HAMAP-Rule MF_00301 SAAS SAAS005280 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00301 SAAS SAAS005280 EMBL ADJ61975.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	threonine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D8IXA0 [UniParc]. Last modified October 5, 2010. Version 1. Checksum: C9231442434CD1E6	FASTA	318	35,785
	10 20 30 40 50 60 MAVFTPVSLE QLSDWLKHFP LGTATSIKGI SSGIENSNFF IGTERGEYVL TLFEKLHIEQ 70 80 90 100 110 120 LPFYLELMRH LAERGIPVPA PVANDKGAIV SLLNDKPAAI VSKLEGQSQL DPQPVHCAAL 130 140 150 160 170 180 GDMLARMHLA AKDFKILQPN LRGLAWWLET TPTVLPFLPA ELGRLLADEV QYQKDFAATA 190 200 210 220 230 240 DYRALPRGPV HADLFRNNAM FVGERLSGIF DFYFAGCDTW LFDLAVTVND WCVDLDTGVL 250 260 270 280 290 300 DLARTEAMLA AYRAVRPFSE AERIAWQPML RAAALRFWLS RLYDFYMPRA AEMLTPHDPT 310 HFERILRLRI AETPPALS

References

[1]

"The genome of Herbaspirillum seropedicae SmR1, an endophytic, nitrogen-fixing, plant-growth promoting beta-Proteobacteria." Pedrosa F.O., Monteiro R.A., Wassem R., Cruz L.M., Ayub R.A., Colauto N.B., Fernandez M.A., Fungaro M.H.P., Grisard E.C., Hungria M., Madeira H.M.F., Nodari R.O., Osaku C.A., Petzl-Erler M.L., Terenzi H., Vieira L.G.E., Almeida M.I.M., Alves L.R. , Arantes O.M.N., Balsanelli E., Barcellos F.G., Baura V.A., Binde D.R., Campo R.J., Chubatsu L.S., Chueire L.M.O., Ciferri R.R., Correa L.C., da Conceicao Silva J.L., Dabul A.N.G., Dambros B.P., Faoro H., Favetti A., Friedermann G., Furlaneto M.C., Gasques L.S., Gimenes C.C.T., Gioppo N.M.R., Glienke-Blanco C., Godoy L.P., Guerra M.P., Karp S., Kava-Cordeiro V., Margarido V.P., Mathioni S.M., Menck-Soares M.A., Murace N.K., Nicolas M.F., Oliveira C.E.C., Pagnan N.A.B., Pamphile J.A., Patussi E.V., Pereira L.F.P., Pereira-Ferrari L., Pinto F.G.S., Precoma C., Prioli A.J., Prioli S.M.A.P., Raittz R.T., Ramos H.J.O., Ribeiro E.M.S.F., Rigo L.U., Rocha C.L.M.S.C., Rocha S.N., Santos K., Satori D., Silva A.G., Simao R.C.G., Soares M.A.M., Souza E.M., Steffens M.B.R., Steindel M., Tadra-Sfeir M.Z., Takahashi E.K., Torres R.A., Valle J.S., Vernal J.I., Vilas-Boas L.A., Watanabe M.A.E., Weiss V.A., Yates M.A., Souza E.M. Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SmR1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002039 Genomic DNA. Translation: ADJ61975.1.
RefSeq	YP_003773883.1. NC_014323.1.
3D structure databases
ProteinModelPortal	D8IXA0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADJ61975; ADJ61975; Hsero_0450.
GeneID	9401051.
KEGG	hse:Hsero_0450.
PATRIC	42359573. VBIHerSer153339_0460.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000004810.
KO	K02204.
Enzyme and pathway databases
BioCyc	HSER757424:GCTT-450-MONOMER.
UniPathway	UPA00050; UER00064.
Family and domain databases
HAMAP	MF_00301. Homoser_kinase_2.
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR005280. Homoserine_kinase_ThrB. IPR011009. Kinase-like_dom. [Graphical view]
Pfam	PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR00938. thrB_alt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

D8IXA0_HERSS

Accession

Primary (citable) accession number: D8IXA0

Entry history

Integrated into UniProtKB/TrEMBL:	October 5, 2010
Last sequence update:	October 5, 2010
Last modified:	May 29, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)